Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Justin G. Lichter"'
Autor:
Ravi Ranjan, Derek J. Dosdall, Kennosuke Yamashita, Rob S. MacLeod, Elyar Ghafoori, Roya Kamali, Eugene Kwan, Eugene G. Kholmovski, Justin G. Lichter
Publikováno v:
Journal of cardiovascular electrophysiology. 30(2)
Introduction Radiofrequency (RF) and cryoablation are routinely used to treat arrhythmias, but the extent and time course of edema associated with the two different modalities is unknown. Our goal was to follow the lesion maturation and edema formati
Autor:
John H.B. Bridge, Gordon F. Tomaselli, Hui Li, Thomas Seidel, Frank B. Sachse, Justin G. Lichter
Publikováno v:
Circulation: Heart Failure. 8:1105-1114
Background— Cardiac resynchronization therapy (CRT) is a major advance for treatment of patients with dyssynchronous heart failure (DHF). However, our understanding of DHF-associated remodeling of subcellular structure and function and their restor
Autor:
Andreas S. Barth, John H.B. Bridge, Justin G. Lichter, Gordon F. Tomaselli, Eric D. Carruth, Takeshi Aiba, Chelsea Mitchell, David A. Kass, Frank B. Sachse
Publikováno v:
Journal of Molecular and Cellular Cardiology. 72:186-195
Sarcomeres are the basic contractile units of cardiac myocytes. Recent studies demonstrated remodeling of sarcomeric proteins in several diseases, including genetic defects and heart failure. Here we investigated remodeling of sarcomeric α-actinin i
Publikováno v:
Annals of biomedical engineering. 44(10)
Measurement of cell shortening is an important technique for assessment of physiology and pathophysiology of cardiac myocytes. Many types of heart disease are associated with decreased myocyte shortening, which is commonly caused by structural and fu
Autor:
Justin G. Lichter, Tatiana Yuzyuk, Hui Li, Mickey R. Miller, Aman Makaju, Junko Shibayama, Jane D. Leavy, James E. Cox, Sarah Franklin, Alexey V. Zaitsev
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0118974 (2015)
PLoS ONE, Vol 10, Iss 3, p e0118974 (2015)
Heart failure (HF) is accompanied by complex alterations in myocardial energy metabolism. Up to 40% of HF patients have dyssynchronous ventricular contraction, which is an independent indicator of mortality. We hypothesized that electromechanical dys
Publikováno v:
Biophysical Journal. 108(2)
Dyssynchronous heart failure (DHF) is associated with structural and functional remodeling in cardiomyocytes from subcellular to whole organ level. Several studies have demonstrated remodeling of Ca2+ signaling and excitation-contraction coupling. Th