Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Justin Fonte"'
Autor:
Kevin Taddei, Justin Fonte, Francoise Suard, Christopher M. Fisher, Domizio Suva, Catriona McLean, Pankaj D. Mehta, Anastazija Gnjec, Colin L. Masters, Judith Miklossy, Joseph Ghika, William S. Brooks, Ralph N. Martins, Giuseppe Verdile
Publikováno v:
Neurobiology of Aging. 24:655-662
Mutations in the gene encoding presenilin 1 (PS-1) account for 50% of early-onset familial Alzheimer’s disease (EOFAD) cases. In this study, we identified two missense mutations in the coding sequence of the presenilin (PS-1) gene in two EOFAD pedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc4280ccbaeaef182c8273991360314
https://doi.org/10.1016/s0197-4580(02)00192-6
https://doi.org/10.1016/s0197-4580(02)00192-6
Publikováno v:
Europe PubMed Central
Macquarie University
Macquarie University
The relationship between amyloid-beta protein (Abeta) metabolism and Alzheimer's disease is currently poorly understood. While it is well known that the generation of Abeta results from enzymatic cleavage of its parent molecule, the amyloid beta prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b8152c6b93aca58e00e65e8d7acca4
https://doi.org/10.3233/jad-2003-5101
https://doi.org/10.3233/jad-2003-5101
Publikováno v:
Journal of Alzheimer's disease : JAD. 3(2)
The most consistent diagnostic neuropathological lesion in Alzheimer's disease (AD) is the senile plaque of which the 4 kD amyloid-beta (Abeta) peptide is the major proteinaceous component. In this study cortical Abeta levels were immunochemically me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4e23943f2b649ab6db69447eae6b28
https://pubmed.ncbi.nlm.nih.gov/12214062
https://pubmed.ncbi.nlm.nih.gov/12214062
Publikováno v:
Frontiers in bioscience : a journal and virtual library. 7
A defining feature of Alzheimer's disease (AD) pathology is the presence of amyloid beta known as A-beta (Abeta) within neuritic plaques of the hippocampus and neocortex of the brain. While early in vitro studies suggested that Abeta could itself be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035f0aec4f4900af083df24d5d655c8a
https://pubmed.ncbi.nlm.nih.gov/11897554
https://pubmed.ncbi.nlm.nih.gov/11897554
Autor:
Leon Flicker, David Lim, Sam Gandy, Justin Fonte, Osvaldo P. Almeida, Anna Waterrus, Ralph N. Martins, Nigel Spry
Publikováno v:
JAMA. 285(17)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098cbeb65c4bbee23143d6cf3d1be672
https://pubmed.ncbi.nlm.nih.gov/11497529
https://pubmed.ncbi.nlm.nih.gov/11497529