Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Justin Farlow"'
Autor:
Seo Hyun Choi, Kaden M. Southard, Zev J. Gartner, Min Kang, Nam Hyeong Kim, Yong Ho Kim, Minsuk Kwak, Anastasios Georgakopoulos, Hyun Jung Lee, Matthew L. Kutys, Minji An, Ramu Gopalappa, Justin Farlow, Daeha Seo, Jinwoo Cheon, Hyongbum Kim, Woon Ryoung Kim, Young-wook Jun, Nikolaos K. Robakis, Annie Lin
Adherens junctions (AJs) create spatially and mechanically discrete microdomains at the interfaces of cells. Using a mechanogenetic platform that generates artificial AJs with controlled protein localization, clustering, and mechanical loading, we re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf45d0e595997dfc1f9bc53a86454747
https://doi.org/10.21203/rs.3.rs-956506/v1
https://doi.org/10.21203/rs.3.rs-956506/v1
Autor:
Minsuk Kwak, Kaden M. Southard, Woon Ryoung Kim, Annie Lin, Nam Hyeong Kim, Ramu Gopalappa, Hyun Jung Lee, Minji An, Seo Hyun Choi, Yunmin Jung, Kunwoo Noh, Justin Farlow, Anastasios Georgakopoulos, Nikolaos K. Robakis, Min K. Kang, Matthew L. Kutys, Daeha Seo, Hyongbum Henry Kim, Yong Ho Kim, Jinwoo Cheon, Zev J. Gartner, Young-wook Jun
Publikováno v:
Nature cell biology. 24(12)
Adherens junctions (AJs) create spatially, chemically and mechanically discrete microdomains at cellular interfaces. Here, using a mechanogenetic platform that generates artificial AJs with controlled protein localization, clustering and mechanical l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e096e17fb403bd683aa9ca400fee448e
https://pubmed.ncbi.nlm.nih.gov/36456828
https://pubmed.ncbi.nlm.nih.gov/36456828
Autor:
Seo Hyun Choi, Hyun Jung Lee, Min K Kang, Nikolaos K. Robakis, Nam Hyeong Kim, Minji An, Woon Ryoung Kim, Justin Farlow, Young-wook Jun, Anastasios Georgakopoulos, Ramu Gopalappa, Jinwoo Cheon, Hyeong Bum Kim, Daeha Seo, Zev J. Gartner, Minsuk Kwak, Kaden M. Southard, Yong Ho Kim
Aberrant cleavage of Notch by γ-secretase is implicated in numerous diseases, but how cleavage is regulated in space and time is unclear. Here, we report that cadherin-based adherens junctions (cadAJs) are sites of high cell-surface γ-secretase act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e9feab218bf47d9305e833a36c71ff9
https://doi.org/10.1101/2020.06.28.176560
https://doi.org/10.1101/2020.06.28.176560
Autor:
Zev J. Gartner, Noel Y. Jee, Justin Farlow, Michael E. Todhunter, Alec E. Cerchiari, Robert J. Weber
Publikováno v:
Current Protocols in Chemical Biology
Tissues are the organizational units of function in metazoan organisms. Tissues comprise an assortment of cellular building blocks, soluble factors, and extracellular matrix (ECM) composed into specific three-dimensional (3-D) structures. The capacit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4220dc037b1b1810e61032e76c06758
https://doi.org/10.1002/cpch.8
https://doi.org/10.1002/cpch.8
Autor:
Maxwell C. Coyle, Alex J. Hughes, Noel Y. Jee, James C. Garbe, Alec E. Cerchiari, Zev J. Gartner, Tejal A. Desai, Mark A. LaBarge, Justin Farlow, Michael E. Todhunter
Publikováno v:
Nature Methods. 12:975-981
Reconstituting tissues from their cellular building blocks facilitates the modeling of morphogenesis, homeostasis and disease in vitro. Here we describe DNA-programmed assembly of cells (DPAC), a method to reconstitute the multicellular organization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe1273b57408f527b878c53df2ff6e3e
https://doi.org/10.1038/nmeth.3553
https://doi.org/10.1038/nmeth.3553
Autor:
A. Paul Alivisatos, Thomas J. Haas, Young-wook Jun, Justin Farlow, Daeha Seo, Ji Wook Kim, Jinwoo Cheon, Hyun Jung Lee, Kaden M. Southard, David B. Litt, Zev J. Gartner, Jung Uk Lee
Publikováno v:
Cell, vol 165, iss 6
Seo, Daeha; Southard, Kaden M; Kim, Ji-Wook; Lee, Hyun Jung; Farlow, Justin; Lee, Jung-Uk; et al.(2016). A Mechanogenetic Toolkit for Interrogating Cell Signaling in Space and Time.. Cell, 165(6), 1507-1518. doi: 10.1016/j.cell.2016.04.045. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/28g6w3fq
Seo, Daeha; Southard, Kaden M; Kim, Ji-Wook; Lee, Hyun Jung; Farlow, Justin; Lee, Jung-Uk; et al.(2016). A Mechanogenetic Toolkit for Interrogating Cell Signaling in Space and Time.. Cell, 165(6), 1507-1518. doi: 10.1016/j.cell.2016.04.045. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/28g6w3fq
Tools capable of imaging and perturbing mechanical signaling pathways with fine spatiotemporal resolution have been elusive, despite their importance in diverse cellular processes. The challenge in developing a mechanogenetic toolkit (i.e., selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c23580434811dfd4d05caa79ccd0b13
https://pubmed.ncbi.nlm.nih.gov/27180907
https://pubmed.ncbi.nlm.nih.gov/27180907
Autor:
Russell Spitzer, Juliet R. Girard, Michael E. Todhunter, Justin Farlow, Geoffrey C. Rollins, Chris R. Fuller, Joanna Lipinski-Kruszka, Emma McCullagh, Hana El-Samad, Dan Lu, Thomas R. Noriega
Publikováno v:
Nature Chemical Biology. 5:699-704
Phenotypic diversity exists even within isogenic populations of cells. Such nongenetic individuality may have wide implications for our understanding of many biological processes. The field of study concerned with the investigation of nongenetic indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9bb4ffa2d609d907021eab2a6654671
https://doi.org/10.1038/nchembio.222
https://doi.org/10.1038/nchembio.222
Publikováno v:
Journal of Visualized Experiments : JoVE
The multivalent nature of commercial quantum dots (QDs) and the difficulties associated with producing monovalent dots have limited their applications in biology, where clustering and the spatial organization of biomolecules is often the object of st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac16af8f86a050f112839f62825cabd
http://europepmc.org/articles/PMC4309134
http://europepmc.org/articles/PMC4309134
Autor:
Jinwoo Cheon, Justin Farlow, A. Paul Alivisatos, Daeha Seo, Ji-wook Kim, Hyun Jung Lee, Young-wook Jun, Zev J. Gartner
Publikováno v:
Biophysical Journal. 106(2)
Notch signaling is a key cell-to-cell communication mechanism during development and in normal tissue maintenance and cancer. Signals exchanged between neighboring cells via Notch can reinforce molecular differences which eventually direct the fate d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58aaa0bad3592c29243d0fa8aa649fb3
Publikováno v:
Nature methods
Gartner, Zev; Jun, Young-Wook; Farlow, J; Seo, D; Broaders, KE; Taylor, MJ; et al.(2013). Formation of targeted monovalent quantum dots by steric exclusion. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/3dv1v3qp
Gartner, Zev; Jun, Young-Wook; Farlow, J; Seo, D; Broaders, KE; Taylor, MJ; et al.(2013). Formation of targeted monovalent quantum dots by steric exclusion. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/3dv1v3qp
Precise control over interfacial chemistry between nanoparticles and other materials remains a significant challenge limiting the broad application of nanotechnology in biology. To address this challenge, we use “Steric Exclusion” to completely c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8d4812ab61484bf5160139f7233ca1
https://hdl.handle.net/21.11116/0000-0003-D488-421.11116/0000-0003-D480-C
https://hdl.handle.net/21.11116/0000-0003-D488-421.11116/0000-0003-D480-C