Zobrazeno 1 - 10
of 412
pro vyhledávání: '"Justin F, Gainor"'
Autor:
Paul E. Hanna, Tianqi Ouyang, Ismail Tahir, Nurit Katz‐Agranov, Qiyu Wang, Lea Mantz, Ian Strohbehn, Daiana Moreno, Destiny Harden, James E. Dinulos, Duru Cosar, Harish Seethapathy, Justin F. Gainor, Sachin J. Shah, Shruti Gupta, David E. Leaf, Florian J. Fintelmann, Meghan E. Sise
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 3, Pp 1187-1198 (2024)
Abstract Background Creatinine‐based estimated glomerular filtration rate (eGFRCRE) may overestimate kidney function in patients with sarcopenia. While cystatin C‐based eGFR (eGFRCYS) is less affected by muscle mass, it may underestimate kidney f
Externí odkaz:
https://doaj.org/article/44af5f6f1ea54b2c8f09c7cb3eb582ac
Autor:
Biagio Ricciuti, MD, PhD, Arielle Elkrief, MD, Jessica Lin, MD, Jianjun Zhang, MD, Joao V. Alessi, MD, Giuseppe Lamberti, MD, PhD, Malini Gandhi, MD, Alessandro Di Federico, MD, Federica Pecci, MD, Xinan Wang, PhD, Maisam Makarem, MD, PhD, Cassio Murilo Hidalgo Filho, MD, Teresa Gorria, MD, Arushi Saini, BS, Cindy Pabon, MD, James Lindsay, PhD, Kathleen L. Pfaff, PhD, Emma L. Welsh, BS, Mizuki Nishino, MD, Lynette M. Sholl, MD, Scott Rodig, MD, Saadettin Kilickap, MD, Petra Rietschel, MD, Debra AG. McIntyre, PhD, Jean-Francois Pouliot, MD, Mehmet Altan, MD, Justin F. Gainor, MD, John V. Heymach, MD, Adam J. Schoenfeld, MD, Mark M. Awad, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 9, Pp 100675- (2024)
Introduction: Responses to first-line programmed cell death protein 1 inhibition vary among patients with metastatic NSCLC and a programmed death-ligand 1 (PD-L1) tumor proportion score (TPS) greater than or equal to 50%. We previously reported impro
Externí odkaz:
https://doaj.org/article/b469726a5a6d43d08be740aa9e8f7bc9
Autor:
Mark Voskoboynik, Justin Moser, Mario Sznol, Amita Patnaik, Amanda Enstrom, Diwakar Davar, Michael Millward, Rachel E Sanborn, Meredith McKean, Justin F Gainor, Nehal Lakhani, Heidi LeBlanc, Stanford L Peng, Heather Thomas, Lori Blanchfield, Michael J Chisamore, Allison Naumovski, Ludimila Cavalcante, Jaspreet S Grewal, Ajita Narayan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)
Background Davoceticept (ALPN-202) is an Fc fusion of a CD80 variant immunoglobulin domain designed to mediate programmed death-ligand 1 (PD-L1)-dependent CD28 co-stimulation while inhibiting the PD-L1 and cytotoxic T-lymphocyte-associated antigen 4
Externí odkaz:
https://doaj.org/article/09d04456db2341698a183766d4d11533
Autor:
Tianjiao Wang, Jean-Marc Navenot, Stavros Rafail, Cynthia Kurtis, Mark Carroll, Marian Van Kerckhoven, Sofie Van Rossom, Kelly Schats, Konstantinos Avraam, Robyn Broad, Karen Howe, Ashley Liddle, Amber Clayton, Ruoxi Wang, Laura Quinn, Joseph P. Sanderson, Cheryl McAlpine, Carly Carozza, Eric Pimpinella, Susan Hsu, Francine Brophy, Erica Elefant, Paige Bayer, Dennis Williams, Marcus O. Butler, Jeffrey M. Clarke, Justin F. Gainor, Ramaswamy Govindan, Victor Moreno, Melissa Johnson, Janet Tu, David S. Hong, George R. Blumenschein, Jr.
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101265- (2024)
T cell receptor (TCR) T cell therapies target tumor antigens in a human leukocyte antigen (HLA)-restricted manner. Biomarker-defined therapies require validation of assays suitable for determination of patient eligibility. For clinical trials evaluat
Externí odkaz:
https://doaj.org/article/4a2c3428294d4a8f91abc7b22ea7bab3
Autor:
Justin M. Cheung, MD, Jiyoon Kang, DO, Beow Y. Yeap, ScD, Jennifer L. Peterson, BS, Andrew Do, BS, Justin F. Gainor, MD, Subba R. Digumarthy, MD, Jessica J. Lin, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 3, Pp 100645- (2024)
Introduction: Central nervous system (CNS) metastases remain a common challenge in patients with ALK-positive NSCLC. We previously reported reinduction of CNS responses using dose-intensified alectinib in two patients with CNS progression on standard
Externí odkaz:
https://doaj.org/article/4045a802fb364d54add361b8d80efe2a
Autor:
Jaime L. Schneider, Khvaramze Shaverdashvili, Mari Mino-Kenudson, Subba R. Digumarthy, Andrew Do, Audrey Liu, Justin F. Gainor, Jochen K. Lennerz, Timothy F. Burns, Jessica J. Lin
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-7 (2023)
Abstract Acquired drug resistance remains a major problem across oncogene-addicted cancers. Elucidation of mechanisms of resistance can inform rational treatment strategies for patients relapsing on targeted therapies while offering insights into tum
Externí odkaz:
https://doaj.org/article/39fd463012fa4aa7af342003242f7782
Autor:
Chrysovalantis Voutouri, C Corey Hardin, Vivek Naranbhai, Mohammad R Nikmaneshi, Melin J Khandekar, Justin F Gainor, Lance L Munn, Rakesh K Jain, Triantafyllos Stylianopoulos
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0301780 (2024)
Critical illness, such as severe COVID-19, is heterogenous in presentation and treatment response. However, it remains possible that clinical course may be influenced by dynamic and/or random events such that similar patients subject to similar injur
Externí odkaz:
https://doaj.org/article/14299f1c215547adae64ad9a199da9f3
Autor:
Wei Zheng, Jing Sun, Jeffrey Weber, Manish R Patel, Brandon Coder, Igor Feldman, Justin F Gainor, Jessica L Geiger, Martin Gutierrez, Joshua Frederick, Celine Robert-Tissot, Robert Meehan, Jack Pollard, Lakshmi Srinivasan, Michelle Brown, Kedar Kirtane, Julie E Bauman, Praveen Aanur, Jeffrey M Clarke, Ricklie A Julian, Aaron J Scott, Moomal Tasneem, Lauren Gerbereux, Andressa Laino, Peijie Hou, Vasudha Sehgal, Hikmat N Daghestani, Howard A Burris
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/ee729db4f6cb4ebfac2f821adca02921
Autor:
Lingzhi Hong, Muhammad Aminu, Shenduo Li, Xuetao Lu, Milena Petranovic, Maliazurina B. Saad, Pingjun Chen, Kang Qin, Susan Varghese, Waree Rinsurongkawong, Vadeerat Rinsurongkawong, Amy Spelman, Yasir Y. Elamin, Marcelo V. Negrao, Ferdinandos Skoulidis, Carl M. Gay, Tina Cascone, Saumil J. Gandhi, Steven H. Lin, Percy P. Lee, Brett W. Carter, Carol C. Wu, Mara B. Antonoff, Boris Sepesi, Jeff Lewis, Don L. Gibbons, Ara A. Vaporciyan, Xiuning Le, J. Jack Lee, Sinchita Roy-Chowdhuri, Mark J. Routbort, Justin F. Gainor, John V. Heymach, Yanyan Lou, Jia Wu, Jianjun Zhang, Natalie I. Vokes
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Immune checkpoint inhibitors with or without chemotherapy are now standard of care for non-small cell lung cancer. However, the benefits of combination vs sequential therapy have not been fully explored. Here, the authors analysed 1,133 patient recor
Externí odkaz:
https://doaj.org/article/8e4eb1b2cf4847c68859d771395453bd
Publikováno v:
Cancer Medicine, Vol 11, Iss 24, Pp 4796-4805 (2022)
Abstract Pulmonary function can predict all‐cause mortality, and chronic obstructive pulmonary disease (COPD) is associated with worse overall survival (OS) in non‐small cell lung cancer (NSCLC) patients. Though pre‐operative lung function is p
Externí odkaz:
https://doaj.org/article/ed033ed9ef5746f493a3e7a676b86bbd