Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Justin E Molloy"'
Autor:
Juha Vahokoski, Lesley J Calder, Andrea J Lopez, Justin E Molloy, Inari Kursula, Peter B Rosenthal
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010408 (2022)
Malaria is responsible for half a million deaths annually and poses a huge economic burden on the developing world. The mosquito-borne parasites (Plasmodium spp.) that cause the disease depend upon an unconventional actomyosin motor for both gliding
Externí odkaz:
https://doaj.org/article/4f48943ad9af4905a7553855890a832d
Autor:
Nicholas A W Bell, Justin E Molloy
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244103 (2020)
We present a fast, inexpensive and robust technique for constructing thin, optically transparent flow-cells with pump-free flow control. Using layers of glass, patterned adhesive tape and polydimethylsiloxane (PDMS) connections, we demonstrate the fa
Externí odkaz:
https://doaj.org/article/b7c2adb29e264b35b1196719866ddb14
Autor:
Karen Baker, Irene A Gyamfi, Gregory I Mashanov, Justin E Molloy, Michael A Geeves, Daniel P Mulvihill
Publikováno v:
eLife, Vol 8 (2019)
Cells respond to changes in their environment through signaling networks that modulate cytoskeleton and membrane organization to coordinate cell-cycle progression, polarized cell growth and multicellular development. Here, we define a novel regulator
Externí odkaz:
https://doaj.org/article/bbfa004fdeba404386462db57bec03b4
Autor:
Gregory I. Mashanov, Justin E. Molloy
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Recent advances in light microscopy have enabled single molecules to be imaged and tracked within living cells and this approach is impacting our understanding of cell biology. Computer modeling and simulation are important adjuncts to the e
Externí odkaz:
https://doaj.org/article/ce59a18dbd5c4a10a121229bd83aa02f
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract The calcium calmodulin protein kinase II (CaMKII) is a multi-subunit ring assembly with a central hub formed by the association domains. There is evidence for hub polymorphism between and within CaMKII isoforms, but the link between polymorp
Externí odkaz:
https://doaj.org/article/182ce7879a3042cfaf64aa32481ae0ac
Autor:
Nicholas A. W. Bell, Justin E. Molloy
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Poly(ADP-ribose) polymerases (PARPs) play key roles in DNA damage repair pathways in eukaryotic cells. Human PARPs 1 and 2 are catalytically activated by damage in the form of both double-strand and single-strand DNA breaks. Recent structural work in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6132fedbb2b1d18bb76744a6518555fa
https://doi.org/10.1073/pnas.2214209120
https://doi.org/10.1073/pnas.2214209120
Autor:
Athinoula Meli, Ann McCormack, Ianina Conte, Qu Chen, James Streetley, Marlene L. Rose, Ruben Bierings, Matthew J. Hannah, Justin E. Molloy, Peter B. Rosenthal, Tom Carter
Publikováno v:
International Journal of Molecular Sciences, 24(5):4553. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4553
International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4553
The assembly of von Willebrand factor (VWF) into ordered helical tubules within endothelial Weibel–Palade bodies (WPBs) is required for the efficient deployment of the protein at sites ofvascular injury. VWF trafficking and storage are sensitive to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75dccba97a4b4387bb753a56d2c3746e
https://pure.eur.nl/en/publications/9c9f3d4b-e881-43e9-925c-5f2ba9665e62
https://pure.eur.nl/en/publications/9c9f3d4b-e881-43e9-925c-5f2ba9665e62
Myosin B (MyoB) is a class 14 myosin expressed in all invasive stages of the malaria parasite, Plasmodium falciparum. It is not associated with the glideosome complex that drives motility and invasion of host cells. During red blood cell invasion, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60149716ae8d0b6aa7670c7171b1fe79
https://doi.org/10.1101/2022.05.28.493848
https://doi.org/10.1101/2022.05.28.493848
Publikováno v:
Journal of Biological Chemistry
The journal of biological chemistry 298(12), 102634 (2022). doi:10.1016/j.jbc.2022.102634
The journal of biological chemistry 298(12), 102634 (2022). doi:10.1016/j.jbc.2022.102634
The journal of biological chemistry 298(12), 102634 (2022). doi:10.1016/j.jbc.2022.102634
Myosin B (MyoB) is a class 14 myosin expressed in all invasive stages of the malaria parasite, Plasmodium falciparum. It is not associated with the glideos
Myosin B (MyoB) is a class 14 myosin expressed in all invasive stages of the malaria parasite, Plasmodium falciparum. It is not associated with the glideos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8480ceeb39dd0ceec69766c1bb34e08e
https://hdl.handle.net/11250/3060960
https://hdl.handle.net/11250/3060960
Autor:
Nigel J. M. Birdsall, Alla Mashanova, Justin E. Molloy, Remigijus Lape, Gregory I. Mashanov, Lucia G. Sivilotti, Tatiana A. Nenasheva
Publikováno v:
Faraday Discussions
Heterogeneity in cell membrane structure, typified by microdomains with different biophysical and biochemical properties, is thought to impact on a variety of cell functions. Integral membrane proteins act as nanometre-sized probes of the lipid envir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6ca715a4373a46d8e7348ee4fd8a3c
https://pubmed.ncbi.nlm.nih.gov/34647559
https://pubmed.ncbi.nlm.nih.gov/34647559