Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Justin Dittmann"'
Autor:
Graeme H. McCormack, Kelsey A. Hanson, Yao Liu, James C. Vickers, Carmen M. Fernandez-Martos, Justin Dittmann, Anna E. King
BackgroundAlzheimer’s disease (AD) has challenged single-target therapeutic strategies, raising the possibility that combined therapies may offer a more effective treatment strategy.ObjectiveThere is substantial evidence for the efficacy of leptin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ad9675df6ac3cab315e811c0c801b91
https://doi.org/10.1101/2020.06.24.168518
https://doi.org/10.1101/2020.06.24.168518
Autor:
Carmen M. Fernandez-Martos, Kelsey A. Hanson, Justin Dittmann, Anna E. King, Rachel A.K. Atkinson, James C. Vickers, Graeme H. McCormack, Yao Liu
Publikováno v:
Current Alzheimer research. 17(14)
Background: Alzheimer’s disease (AD) has challenged single-target therapeutic strategies, raising the possibility that combined therapies may offer a more effective treatment strategy. Objective: There is substantial evidence for the efficacy of le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6413f7ca61e86ba5637393522dba461
https://pubmed.ncbi.nlm.nih.gov/33602093
https://pubmed.ncbi.nlm.nih.gov/33602093
Autor:
Carmen M. Fernandez-Martos, Kelsey Hanson, James C. Vickers, Justin Dittmann, Anna E. King, Anna Brain
Publikováno v:
Metabolic Brain Disease. 33:1097-1110
Disruption of leptin signalling has been implicated as playing a role in the development of Alzheimer's disease (AD). Leptin has previously been shown to be affected by amyloid-beta (Aβ)-related signalling; however, pathways that link leptin to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b50c6e47cc1a7ccddfc57475952e723
https://doi.org/10.1007/s11011-018-0203-9
https://doi.org/10.1007/s11011-018-0203-9
Autor:
Darko Stefanovski, Vahe Mooradian, Karyn J. Catalano, Jenny D. Chiu, Stella P. Kim, Justin Dittmann, Dan Zheng, Orison O. Woolcott, Morvarid Kabir, Cathryn M. Kolka, Richard N. Bergman, Gregg W. Van Citters, Sophia Yae, Maya Lottati, Marilyn Ader, Viorica Ionut, Lisa N. Harrison, Huiwen Liu, Katrin Hücking, Joyce M. Richey, Isabel R. Hsu, Martin Ellmerer, Ana Valeria B. Castro
Publikováno v:
Obesity. 22:1238-1245
Objective Insulin resistance is a powerful risk factor for Type 2 diabetes and a constellation of chronic diseases, and is most commonly associated with obesity. We examined if factors other than obesity are more substantial predictors of insulin sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25b7f067ff6cce01815df43067e4ee65
https://doi.org/10.1002/oby.20625
https://doi.org/10.1002/oby.20625
Autor:
Carmen M. Fernandez-Martos, James C. Vickers, Mathew J. Summers, Justin Dittmann, Anna E. King, Kimberley E. Stuart
Publikováno v:
The Journal of comparative neurology. 525(8)
Early-life cognitive enrichment may reduce the risk of experiencing cognitive deterioration and dementia in later-life. However, an intervention to prevent or delay dementia is likely to be taken up in mid to later-life. Hence, we investigated the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e796bdbbdfa885437d632479fdc10a0
https://pubmed.ncbi.nlm.nih.gov/27987205
https://pubmed.ncbi.nlm.nih.gov/27987205
Autor:
Javier Carrasco, Johanne W. Asmussen, Carolyn E. King, Justin Dittmann, Milena Penkowa, Lyn Beazley, Melinda Fitzgerald, James C. Vickers, Sarah A. Dunlop, Adrian K. West, Carole A. Bartlett, SJ Fung, Meng Inn Chuah, Juan Hidalgo, Yee Kee J. Leung, Adam K. Walker, Roger S. Chung
Publikováno v:
Journal of Biological Chemistry. 283:15349-15358
A number of intracellular proteins that are protective after brain injury are classically thought to exert their effect within the expressing cell. The astrocytic metallothioneins (MT) are one example and are thought to act via intracellular free rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80d895149d5615eb6b9c02ef28e67fda
https://doi.org/10.1074/jbc.m708446200
https://doi.org/10.1074/jbc.m708446200
Publikováno v:
Neurotoxicity Research. 7:87-93
In recent years metallothionein (MT) biology has moved from investigation of its ability to protect against environmental heavy metals to a wider appreciation of its role in responding to cellular stress, whether as a consequence of normal function,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d0629197bbd9d7970ddd3850fecb13
https://doi.org/10.1007/bf03033779
https://doi.org/10.1007/bf03033779
Autor:
Roger S. Chung, Adrian K. West, James C. Vickers, Justin Dittmann, Meng Inn Chuah, Paul A. Adlard
Publikováno v:
Journal of Neurochemistry. 88:454-461
Recent data suggests that metallothioneins (MTs) are major neuroprotective proteins within the CNS. In this regard, we have recently demonstrated that MT-IIA (the major human MT-I/-II isoform) promotes neural recovery following focal cortical brain i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fb16d62b5876e6a635099c35b1831ad
https://doi.org/10.1046/j.1471-4159.2003.02193.x
https://doi.org/10.1046/j.1471-4159.2003.02193.x
Publikováno v:
Acta Neuropathologica Communications
Background: Axon degeneration, a key pathological event in many neurodegenerative diseases and injury, can be induced by somatodendritic excitotoxin exposure. It is currently unclear, however, whether excitotoxin-induced axon degeneration is mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af686666db932a2d480bc56471ff49cf
https://doi.org/10.1186/2051-5960-1-59
https://doi.org/10.1186/2051-5960-1-59
Autor:
Marilyn, Ader, Darko, Stefanovski, Stella P, Kim, Joyce M, Richey, Viorica, Ionut, Karyn J, Catalano, Katrin, Hucking, Martin, Ellmerer, Gregg, Van Citters, Isabel R, Hsu, Jenny D, Chiu, Orison O, Woolcott, Lisa N, Harrison, Dan, Zheng, Maya, Lottati, Cathryn M, Kolka, Vahe, Mooradian, Justin, Dittmann, Sophia, Yae, Huiwen, Liu, Ana Valeria B, Castro, Morvarid, Kabir, Richard N, Bergman
Publikováno v:
Obesity (Silver Spring, Md.)
OBJECTIVE Insulin resistance is a powerful risk factor for Type 2 diabetes and a constellation of chronic diseases, and is most commonly associated with obesity. We examined if factors other than obesity are more substantial predictors of insulin sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f969d22178cb9c464c116b5efac1cc8
https://pubmed.ncbi.nlm.nih.gov/24123967
https://pubmed.ncbi.nlm.nih.gov/24123967