Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Justin D. Shin"'
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102513- (2023)
Summary: Memory generalization is the ability to abstract knowledge from prior experiences and is critical for flexible behavior in novel situations. Here, we describe a protocol for simultaneous recording of hippocampal (area CA1)-prefrontal cortica
Externí odkaz:
https://doaj.org/article/f73a5507a65d4dd3ac5084d1b920f850
Geometric transformation of cognitive maps for generalization across hippocampal-prefrontal circuits
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112246- (2023)
Summary: The ability to abstract information to guide decisions during navigation across changing environments is essential for adaptation and requires the integrity of the hippocampal-prefrontal circuitry. The hippocampus encodes navigational inform
Externí odkaz:
https://doaj.org/article/6a695717a3fa44d1b25c88104e7d7bb1
Publikováno v:
eLife, Vol 13 (2024)
During both sleep and awake immobility, hippocampal place cells reactivate time-compressed versions of sequences representing recently experienced trajectories in a phenomenon known as replay. Intriguingly, spontaneous sequences can also correspond t
Externí odkaz:
https://doaj.org/article/de1ef9b2577d46fc84ef8dd13815dcaa
Publikováno v:
eLife, Vol 10 (2021)
The prefrontal cortex and hippocampus are crucial for memory-guided decision-making. Neural activity in the hippocampus exhibits place-cell sequences at multiple timescales, including slow behavioral sequences (~seconds) and fast theta sequences (~10
Externí odkaz:
https://doaj.org/article/d4f5f4261ffd47e2963114f9c304f631
Publikováno v:
The Journal of Neuroscience. 39:4550-4565
Interactions between the hippocampus (area CA1) and prefrontal cortex (PFC) are crucial for memory-guided behavior. Theta oscillations (∼8 Hz) underlie a key physiological mechanism for mediating these coordinated interactions, and theta oscillator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff9dd8322a38476273a620a0f7a79f1
https://doi.org/10.1523/jneurosci.0106-19.2019
https://doi.org/10.1523/jneurosci.0106-19.2019
Rapid eye movement (REM) sleep is known to play a role in hippocampally-dependent memory, yet the activity and development of hippocampal neuronal ensembles during this state is not well understood. Here we investigated patterning of CA1 place cell a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70a91afa4f200070da495be87ff4d637
https://doi.org/10.1101/2021.04.15.439854
https://doi.org/10.1101/2021.04.15.439854
The prefrontal cortex and hippocampus are crucial for memory-guided decision-making. Neural activity in the hippocampus exhibits place-cell sequences at multiple timescales, including slow behavioral sequences (∼seconds) and fast theta sequences (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64e95880d05be6cfd1f31e5e71913408
https://doi.org/10.1101/2020.10.17.343699
https://doi.org/10.1101/2020.10.17.343699
SUMMARYSpatial learning requires remembering and choosing paths to goals. Hippocampal place cells replay spatial paths during immobility in reverse and forward order, offering a potential mechanism. However, how replay mediates both goal-directed lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f14c02d7cf9521079013fc3f2986f2c
Autor:
Shantanu P. Jadhav, Justin D. Shin
Publikováno v:
Current Opinion in Neurobiology. 40:161-169
The hippocampus and prefrontal cortex are critical for learning and memory-guided behavior, but neural mechanisms underlying their coordinated operation are currently unclear. Recent evidence indicates that different network activity patterns, each m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871814e9a0ff1d939a78401229cf8bd9
https://doi.org/10.1016/j.conb.2016.07.015
https://doi.org/10.1016/j.conb.2016.07.015