Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Justin D. Kim"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Tauopathies are a group of neurodegenerative diseases, which include frontotemporal dementia (FTD) and Alzheimer’s disease (AD), broadly defined by the development of tau brain aggregates. Both missense and splicing tau mutations can directly cause
Externí odkaz:
https://doaj.org/article/2536b32ef5984488bb38d07bb9f3d1f5
Autor:
Yuxing Xia, Stefan Prokop, Kimberly-Marie M. Gorion, Justin D. Kim, Zachary A. Sorrentino, Brach M. Bell, Alyssa N. Manaois, Paramita Chakrabarty, Peter Davies, Benoit I. Giasson
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract Tau protein abnormally aggregates in tauopathies, a diverse group of neurologic diseases that includes Alzheimer’s disease (AD). In early stages of disease, tau becomes hyperphosphorylated and mislocalized, which can contribute to its aggr
Externí odkaz:
https://doaj.org/article/9267b6611e3e4525a29fc05172e583f1
Autor:
Alyssa N. Manaois, Yuxing Xia, Brach M. Bell, Peter Davies, Kimberly-Marie M. Gorion, Zachary A. Sorrentino, Benoit I. Giasson, Stefan Prokop, Paramita Chakrabarty, Justin D. Kim
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Tau protein abnormally aggregates in tauopathies, a diverse group of neurologic diseases that includes Alzheimer’s disease (AD). In early stages of disease, tau becomes hyperphosphorylated and mislocalized, which can contribute to its aggregation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f7ac3758207bf1c0983d92e2926261
http://europepmc.org/articles/PMC7310041
http://europepmc.org/articles/PMC7310041
Autor:
Yuxing Xia, Kevin H. Strang, Justin D. Kim, Zachary A. Sorrentino, Cara J. Riffe, Benoit I. Giasson
Publikováno v:
J Biol Chem
tau is a microtubule (MT)-associated protein that promotes tubulin assembly and stabilizes MTs by binding longitudinally along the MT surface. tau can aberrantly aggregate into pathological inclusions that define Alzheimer's disease, frontotemporal d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c67c9b6b87186292e4561d7eadc1d120
https://pubmed.ncbi.nlm.nih.gov/31653695
https://pubmed.ncbi.nlm.nih.gov/31653695
Thesis (M.S.)--Pennsylvania State University, 2009.
Mode of access: World Wide Web. Thesis advisor: Seungjin Kim.
Mode of access: World Wide Web. Thesis advisor: Seungjin Kim.
