Zobrazeno 1 - 10
of 490
pro vyhledávání: '"Justin D, Lathia"'
Autor:
Rashmi Bharti, Goutam Dey, Debjit Khan, Alex Myers, Olivia G. Huffman, Caner Saygin, Chad Braley, Elliott Richards, Naseer Sangwan, Belinda Willard, Justin D. Lathia, Paul L. Fox, Feng Lin, Babal Kant Jha, J. Mark Brown, Jennifer S. Yu, Mohammed Dwidar, Amy Joehlin-Price, Roberto Vargas, Chad M. Michener, Michelle S. Longworth, Ofer Reizes
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-23 (2024)
Abstract Background Platinum resistance is the primary cause of poor survival in ovarian cancer (OC) patients. Targeted therapies and biomarkers of chemoresistance are critical for the treatment of OC patients. Our previous studies identified cell su
Externí odkaz:
https://doaj.org/article/adfec356b7014a638df6edb322f5b4fb
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 3, Pp 200853- (2024)
Pleomorphic xanthoastrocytoma (PXA) is a rare pediatric low-grade glioma (pLGG), of which 60%–80% exhibit the BRAF V600E mutation, that enhances the aggressiveness and progression to an eventual pediatric high-grade glioma (pHGG). Despite the aggre
Externí odkaz:
https://doaj.org/article/ecccf0521903488792b99183c0963895
Autor:
Ganesh Shenoy, Becky Slagle-Webb, Chachrit Khunsriraksakul, Bhavyata Pandya Shesh, Jingqin Luo, Vladimir Khristov, Nataliya Smith, Alireza Mansouri, Brad E. Zacharia, Sheldon Holder, Justin D. Lathia, Jill S. Barnholtz-Sloan, James R. Connor
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The association between anemia and outcomes in glioblastoma patients is unclear. We analyzed data from 1346 histologically confirmed adult glioblastoma patients in the TriNetX Research Network. Median hemoglobin and hematocrit levels were qu
Externí odkaz:
https://doaj.org/article/a9d3c20eb2d84732ac22809af3797fa9
Autor:
Rakhee Banerjee, Chase J. Wehrle, Zeneng Wang, Jennifer D. Wilcox, Vinayak Uppin, Venkateshwari Varadharajan, Marko Mrdjen, Courtney Hershberger, Ofer Reizes, Jennifer S. Yu, Justin D. Lathia, Daniel M. Rotroff, Stanley L. Hazen, W. H. Wilson Tang, Federico Aucejo, J. Mark Brown
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 1946 (2024)
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide. The gut microbiome has been implicated in outcomes for HCC, and gut microbe-derived products may serve as potential non-invasive indices for early HCC detection. Thi
Externí odkaz:
https://doaj.org/article/a62200dc1b60493abf45e69dac2752b1
Autor:
Christine O’Connor, Justin D. Lathia
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 1, Pp 200776- (2024)
Externí odkaz:
https://doaj.org/article/5d61948907a3468ba198daf8ddcf64bf
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002295 (2023)
Cancer stem cells drive tumor growth and survival via self-renewal and therapeutic resistance, but the upstream mechanisms are not well defined. In this issue of PLOS Biology, a study in colon cancer reveals a new signalling network that links epigen
Externí odkaz:
https://doaj.org/article/3c78a5a10ba144b49943c87807187a2a
Autor:
Tyler J. Alban, Matthew M. Grabowski, Balint Otvos, Defne Bayik, Wesley Wang, Ajay Zalavadia, Vlad Makarov, Katie Troike, Mary McGraw, Anja Rabljenovic, Adam Lauko, Chase Neumann, Gustavo Roversi, Kristin A. Waite, Gino Cioffi, Nirav Patil, Thuy T. Tran, Kathleen McCortney, Alicia Steffens, C. Marcela Diaz, J. Mark Brown, Kathleen M. Egan, Craig M. Horbinski, Jill S. Barnholtz-Sloan, Prajwal Rajappa, Michael A. Vogelbaum, Richard Bucala, Timothy A. Chan, Manmeet S. Ahluwalia, Justin D. Lathia
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
Intratumoral heterogeneity is a defining hallmark of glioblastoma, driving drug resistance and ultimately recurrence. Many somatic drivers of microenvironmental change have been shown to affect this heterogeneity and, ultimately, the treatment respon
Externí odkaz:
https://doaj.org/article/235cfdd3465841ec8a0ca9c96d6c14cb
Autor:
Hye-Min Jeon, Young Taek Oh, Yong Jae Shin, Nakho Chang, Donggeun Kim, Donghun Woo, Yoon Yeup, Kyeung Min Joo, Heejin Jo, Heekyoung Yang, Jin-Ku Lee, Wonyoung Kang, Jason Sa, Won Jun Lee, James Hale, Justin D. Lathia, Benjamin Purow, Myung Jin Park, Jong Bae Park, Do-Hyun Nam, Jeongwu Lee
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 39, Iss , Pp 100894- (2023)
Recent studies indicate that signaling molecules traditionally associated with central nervous system function play critical roles in cancer. Dopamine receptor signaling is implicated in various cancers including glioblastoma (GBM) and it is a recogn
Externí odkaz:
https://doaj.org/article/7d738e1c015644aab95a1aed1b43c8a9
Autor:
Chelsea U Kidwell, Joseph R Casalini, Soorya Pradeep, Sandra D Scherer, Daniel Greiner, Defne Bayik, Dionysios C Watson, Gregory S Olson, Justin D Lathia, Jarrod S Johnson, Jared Rutter, Alana L Welm, Thomas A Zangle, Minna Roh-Johnson
Publikováno v:
eLife, Vol 12 (2023)
Recent studies reveal that lateral mitochondrial transfer, the movement of mitochondria from one cell to another, can affect cellular and tissue homeostasis. Most of what we know about mitochondrial transfer stems from bulk cell studies and have led
Externí odkaz:
https://doaj.org/article/fdb6b4e3161146a9867ad80d5b342202
Autor:
Yuan Hou, Yadi Zhou, Michaela U. Gack, Justin D. Lathia, Asha Kallianpur, Reena Mehra, Timothy A. Chan, Jae U. Jung, Lara Jehi, Charis Eng, Feixiong Cheng
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract Sex differences in the susceptibility of SARS-CoV-2 infection and severity have been controversial, and the underlying mechanisms of COVID-19 in a sex-specific manner remain understudied. Here we inspected sex differences in SARS-CoV-2 infec
Externí odkaz:
https://doaj.org/article/aa08f02b55bc428c9b9e571504963684