Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Justin C. Thomas"'
Publikováno v:
Endocrine Practice. 29:S12-S13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52d08b8e9346cf0fc3897374a3be4fe1
https://doi.org/10.1016/j.eprac.2023.03.032
https://doi.org/10.1016/j.eprac.2023.03.032
Autor:
Liang Fang, Galen H. Shi, Tingting Wang, Xia Dong, Sharon L. Shinkle, Cathy Zhao, Michael C. Victor, Justin C. Thomas, Coralie Adele Richard
Publikováno v:
PDA Journal of Pharmaceutical Science and Technology. 74:674-687
Given the surging interest in developing prefilled syringe and autoinjector combination products, investment in an early compatibility assessment is critical to prevent unwarranted drug/container closure interactions and avoid potential reformulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f8de06a7daea180adbcbb9026c6bb7
https://doi.org/10.5731/pdajpst.2020.011627
https://doi.org/10.5731/pdajpst.2020.011627
Publikováno v:
Protein Instability at Interfaces During Drug Product Development ISBN: 9783030571764
Biologics subjected to interfacial stress can generate a diverse assortment of aggregated species ranging in size from dimers and other soluble aggregates, through subvisible or micrometer-sized particles, to particles in the hundreds of micrometers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::471e040ed28884ef66301c6e2b23cdf7
https://doi.org/10.1007/978-3-030-57177-1_8
https://doi.org/10.1007/978-3-030-57177-1_8
Autor:
Linda O. Narhi, Daniel LaCasse, Jinjiang Li, Raymond S. Tu, Justin C. Thomas, Susan Jordan, Xiaodong Chen, Evgenyi Shalaev, Mary Elizabeth Krause, Ian C. Shieh, Weiguo Dai, Min Huang, Lily Zhu, John J. Hill, Yuan Cheng, Songyan Zheng
Publikováno v:
The AAPS Journal
Biologic products encounter various types of interfacial stress during development, manufacturing, and clinical administration. When proteins come in contact with vapor-liquid, solid-liquid, and liquid-liquid surfaces, these interfaces can significan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b05fec99158a3b1cfad5aaec2a83d07
https://doi.org/10.1208/s12248-019-0312-3
https://doi.org/10.1208/s12248-019-0312-3
Autor:
John Karanicolas, Erin K. Sully, Christopher M. Singer, Nicholas J. Mantis, Donald J. Jacobs, Justin C. Thomas, Sangeeta B. Joshi, Lei Hu, David B. Volkin, C. Russell Middaugh, Newton Wahome, Jianwen Fang
Publikováno v:
Journal of Pharmaceutical Sciences. 105:1603-1613
RiVax is a candidate ricin toxin subunit vaccine antigen that has proven to be safe in human Phase I clinical trials. In this study we introduced double and triple cavity-filling point mutations into the RiVax antigen with the expectation that stabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6479a83368db79674aeca079a5cafc
https://doi.org/10.1016/j.xphs.2016.02.009
https://doi.org/10.1016/j.xphs.2016.02.009
Autor:
Nicholas J. Mantis, C. Russell Middaugh, John Karanicolas, David B. Volkin, Jianwen Fang, Joanne M. O’Hara, Justin C. Thomas, Lei Hu, Robert N. Brey, Sangeeta B. Joshi, Fei P. Gao
Publikováno v:
Human Vaccines & Immunotherapeutics. 9:744-752
There is great interest in the design and development of highly thermostable and immunogenic protein subunit vaccines for biodefense. In this study, we used two orthogonal and complementary computational protein design approaches to generate a series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382f51f5588cec988d2af76242948a1c
https://doi.org/10.4161/hv.22998
https://doi.org/10.4161/hv.22998
Publikováno v:
Biomaterials. 30:867-878
Eye drops are inefficient means of delivering ophthalmic drugs because of limited bioavailability and these can cause significant side effects due to systemic uptake of the drug. The bioavailability for ophthalmic drugs can be increased significantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ecdf3dcbea2545c8c69632c92ec3598
https://doi.org/10.1016/j.biomaterials.2008.10.032
https://doi.org/10.1016/j.biomaterials.2008.10.032
Research Communication: Glutamine and Barrier Function in Cultured Caco-2 Epithelial Cell Monolayers
Publikováno v:
The Journal of Nutrition. 133:2176-2179
Dietary glutamine (Gln) has been shown to be important for maintenance of the intestinal barrier. To investigate the role of the epithelium in this Gln dependence, Caco-2 cells were raised on semipermeable membranes under conditions that model differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d774a98c391c36c14fffc3611bf9a64
https://doi.org/10.1093/jn/133.7.2176
https://doi.org/10.1093/jn/133.7.2176
Publikováno v:
Advances in Delivery Science and Technology ISBN: 9781493914166
The analysis of the structural integrity of biotechnology products and macromolecular systems has become increasingly sophisticated. With regard to vaccines, the major problem has been the complexity of their antigen component(s). Despite this, vacci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9395a230091214e8de382e0b4d8fd4b7
https://doi.org/10.1007/978-1-4939-1417-3_20
https://doi.org/10.1007/978-1-4939-1417-3_20