Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Justin C. Roth"'
Autor:
Chun-Yu Chen, Mohammed G Ghonime, Uksha Saini, Michael C Kelly, Justin C Roth, Pin-Yi Wang, Katherine Miller, Ilse Hernandez-Aguirre, Yeaseul Kim, Xiaokui Mo, Joseph R Stanek, Tim Cripe, Elaine Mardis, Kevin A Cassady
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/000e2ddeb46142639945f4ab424b5abd
Autor:
James M. Markert, Elaine R. Mardis, G. Yancey Gillespie, Richard J. Whitley, Inmaculada B. Aban, Jianmei W. Leavenworth, Nripesh Prasad, Anthony R. Miller, Kristen Leraas, Kathleen M. Schieffer, Jennifer Clements, Justin C. Roth, Kevin A. Cassady, Katherine E. Miller
Purpose:Previously, clinical trials of experimental virotherapy for recurrent glioblastoma multiforme (GBM) demonstrated that inoculation with a conditionally replication–competent Δγ134.5 oncolytic herpes simplex virus (oHSV), G207, was safe. Fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351323d8d2316f8ac4bd44f2b517dfba
https://doi.org/10.1158/1078-0432.c.6531350
https://doi.org/10.1158/1078-0432.c.6531350
Autor:
James M. Markert, Elaine R. Mardis, G. Yancey Gillespie, Richard J. Whitley, Inmaculada B. Aban, Jianmei W. Leavenworth, Nripesh Prasad, Anthony R. Miller, Kristen Leraas, Kathleen M. Schieffer, Jennifer Clements, Justin C. Roth, Kevin A. Cassady, Katherine E. Miller
Supplementary Figure from Immune Activity and Response Differences of Oncolytic Viral Therapy in Recurrent Glioblastoma: Gene Expression Analyses of a Phase IB Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8b4f855353a2cc00917241c8511171
https://doi.org/10.1158/1078-0432.22484192
https://doi.org/10.1158/1078-0432.22484192
Autor:
James M. Markert, Elaine R. Mardis, G. Yancey Gillespie, Richard J. Whitley, Inmaculada B. Aban, Jianmei W. Leavenworth, Nripesh Prasad, Anthony R. Miller, Kristen Leraas, Kathleen M. Schieffer, Jennifer Clements, Justin C. Roth, Kevin A. Cassady, Katherine E. Miller
Supplementary Data from Immune Activity and Response Differences of Oncolytic Viral Therapy in Recurrent Glioblastoma: Gene Expression Analyses of a Phase IB Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12bbb80a57f60bf6316e87c35549db5f
https://doi.org/10.1158/1078-0432.22484198
https://doi.org/10.1158/1078-0432.22484198
Autor:
Katherine E. Miller, Kevin A. Cassady, Justin C. Roth, Jennifer Clements, Kathleen M. Schieffer, Kristen Leraas, Anthony R. Miller, Nripesh Prasad, Jianmei W. Leavenworth, Inmaculada B. Aban, Richard J. Whitley, G. Yancey Gillespie, Elaine R. Mardis, James M. Markert
Publikováno v:
Clin Cancer Res
Purpose: Previously, clinical trials of experimental virotherapy for recurrent glioblastoma multiforme (GBM) demonstrated that inoculation with a conditionally replication–competent Δγ134.5 oncolytic herpes simplex virus (oHSV), G207, was safe. F
Autor:
David C Gaston, Carl I Odom, Li Li, James M Markert, Justin C Roth, Kevin A Cassady, Richard J Whitley, Jacqueline N Parker
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81768 (2013)
Oncolytic type-1 herpes simplex viruses (oHSVs) lacking the γ134.5 neurovirulence gene are being evaluated for treatment of a variety of malignancies. oHSVs replicate within and directly kill permissive cancer cells. To augment their anti-tumor acti
Externí odkaz:
https://doaj.org/article/021ce7ecfa354fe0a13fd4e1fdbd340e
Autor:
Michael O Alberti, Justin C Roth, Mourad Ismail, Yuko Tsuruta, Edward Abraham, Larisa Pereboeva, Stanton L Gerson, David T Curiel
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37812 (2012)
The gene therapy field is currently limited by the lack of vehicles that permit efficient gene delivery to specific cell or tissue subsets. Native viral vector tropisms offer a powerful platform for transgene delivery but remain nonspecific, requirin
Externí odkaz:
https://doaj.org/article/285f7b74aa434245849e2062d8547d0e
Autor:
Mohammed G. Ghonime, G. Yancey Gillespie, Amish C. Shah, Josh Jackson, Kevin A. Cassady, James M. Markert, Ute Saunders, Justin C. Roth, Jennifer M. Coleman, Mao Li
Publikováno v:
Translational Oncology, Vol 11, Iss 1, Pp 86-93 (2018)
Malignant gliomas are the most common primary brain tumor and are characterized by rapid and highly invasive growth. Because of their poor prognosis, new therapeutic strategies are needed. Oncolytic virotherapy (OV) is a promising strategy for treati
Autor:
Ilse Hernandez-Aguirre, Yeaseul Kim, Chun-Yu Chen, Joseph Stanek, Uksha Saini, Michael C Kelly, Justin C. Roth, Katherine E. Miller, Elaine R. Mardis, Pin-Yi Wang, Tim Cripe, Xiaokui Mo, Mohammed G. Ghonime, Kevin A. Cassady
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
BackgroundOncolytic virotherapy (OV) is an immunotherapy that incorporates viral cancer cell lysis with engagement of the recruited immune response against cancer cells. Pediatric solid tumors are challenging targets because they contain both an iner
Autor:
M. R. Chambers, Mark N. Prichard, James M. Markert, Trent Shoeb, Kevin A. Cassady, Justin C. Roth, Jennifer M. Coleman, G. Yancey Gillespie, David F. Bauer
Publikováno v:
Molecular Therapy Oncolytics
Molecular Therapy: Oncolytics, Vol 5, Iss C, Pp 1-10 (2017)
Molecular Therapy: Oncolytics, Vol 5, Iss C, Pp 1-10 (2017)
Oncolytic herpes simplex virus (oHSV) type I constructs are investigational anti-neoplastic agents for a variety of malignancies, including malignant glioma. Clinical trials to date have supported the safety of these agents even when directly adminis