Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Justin C. Rolando"'
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-22 (2020)
Abstract Background The upper gastrointestinal tract plays a prominent role in human physiology as the primary site for enzymatic digestion and nutrient absorption, immune sampling, and drug uptake. Alterations to the small intestine microbiome have
Externí odkaz:
https://doaj.org/article/0fb3a54aad464e53a370d96aa213d934
Autor:
Asher Preska Steinberg, Sujit S Datta, Thomas Naragon, Justin C Rolando, Said R Bogatyrev, Rustem F Ismagilov
Publikováno v:
eLife, Vol 8 (2019)
The lumen of the small intestine (SI) is filled with particulates: microbes, therapeutic particles, and food granules. The structure of this particulate suspension could impact uptake of drugs and nutrients and the function of microorganisms; however
Externí odkaz:
https://doaj.org/article/f971f3626cf6456c96b82733e2c88f10
Autor:
Nathan G. Schoepp, Rustem F. Ismagilov, Matthew M. Cooper, Olusegun O. Soge, Jeffrey D. Klausner, Justin C. Rolando, Emily S. Savela
Publikováno v:
PLoS Biology, Vol 18, Iss 3, p e3000651 (2020)
PLoS Biology
PLoS Biology
Rapid antibiotic susceptibility testing (AST) for Neisseria gonorrhoeae (Ng) is critically needed to counter widespread antibiotic resistance. Detection of nucleic acids in genotypic AST can be rapid, but it has not been successful for β-lactams (th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daed3814a554a2c1735a773fdf1bc683
https://doaj.org/article/fcd540bc4dc348298ddb1b8d55f285d1
https://doaj.org/article/fcd540bc4dc348298ddb1b8d55f285d1
Publikováno v:
Poster Presentations.
Background Designing diagnostic tools to perform phenotypic antimicrobial susceptibility testing (AST) at the point-of-care (POC) is a vital step in tackling the global threat of antimicrobial resistance. Gonorrhea infections with resistance to the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a08a9ff77a59982f4821eb1b4442fa2a
https://doi.org/10.1136/sextrans-2019-sti.729
https://doi.org/10.1136/sextrans-2019-sti.729
Publikováno v:
Analytical Chemistry
Real-time, isothermal, digital nucleic acid amplification is emerging as an attractive approach for a multitude of applications including diagnostics, mechanistic studies, and assay optimization. Unfortunately, there is no commercially available and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44dd47c411d66352d288be09a7cc0e4d
https://resolver.caltech.edu/CaltechAUTHORS:20181221-105356677
https://resolver.caltech.edu/CaltechAUTHORS:20181221-105356677
Autor:
Said R. Bogatyrev, Rustem F. Ismagilov, Asher Preska Steinberg, Thomas Naragon, Justin C. Rolando, Sujit S. Datta
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
The lumen of the small intestine (SI) is filled with particulates: microbes, therapeutic particles, and food granules. The structure of this particulate suspension could impact uptake of drugs and nutrients and the function of microorganisms; however
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa2244a9827cf6b2d9fad6fd2fb20dd3
https://doi.org/10.1101/490920
https://doi.org/10.1101/490920
Publikováno v:
Nucleic acids research, 48(7):e42
Nucleic Acids Research
Nucleic Acids Research
Isothermal amplification assays, such as loop-mediated isothermal amplification (LAMP), show great utility for the development of rapid diagnostics for infectious diseases because they have high sensitivity, pathogen-specificity and potential for imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a02f1d41f5724b2132c872445fc88feb
https://doi.org/10.1093/nar/gkaa099
https://doi.org/10.1093/nar/gkaa099
Autor:
Matt Otis, Chris Bock, Sheela Waugh, Sheri K. Wilcox, Jonathan D. Vaught, Justin C. Rolando, Daniel J. Schneider, Tim Fitzwater, Jeffrey D. Carter, Bruce E. Eaton
Publikováno v:
Journal of the American Chemical Society. 132(12)
Six new 5-position modified dUTP derivatives connected by a unique amide linkage were synthesized and tested for compatibility with the enzymatic steps of in vitro selection. Six commercially available DNA polymerases were tested for their ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75262d958249be7735d981a35240e3c
https://pubmed.ncbi.nlm.nih.gov/20201573
https://pubmed.ncbi.nlm.nih.gov/20201573
Autor:
Emily S Savela, Nathan G Schoepp, Matthew M Cooper, Justin C Rolando, Jeffrey D Klausner, Olusegun O Soge, Rustem F Ismagilov
Publikováno v:
PLoS Biology, Vol 18, Iss 3, p e3000651 (2020)
Rapid antibiotic susceptibility testing (AST) for Neisseria gonorrhoeae (Ng) is critically needed to counter widespread antibiotic resistance. Detection of nucleic acids in genotypic AST can be rapid, but it has not been successful for β-lactams (th
Externí odkaz:
https://doaj.org/article/fcd540bc4dc348298ddb1b8d55f285d1