Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Justin C. Grindley"'
Autor:
Qin Ruan, Scott M. MacDonnell, Wen Zhang, Theodore J. Kaplan, Rebecca Peyser, Gabor Halasz, Yi Wei, Kishor Devalaraja-Narashimha, Morton Lori C, Yong Kim, Christina Adler, Min Ni, Yinglin Gao, Luis Cheng, Justin C. Grindley
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 61:74-85
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disorder driven by unrelenting extracellular matrix deposition. Fibroblasts are recognized as the central mediators of extracellular matrix production in IPF; however, the characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05f0c1bdb5dae7946d12843ff47f8af6
https://doi.org/10.1165/rcmb.2018-0313oc
https://doi.org/10.1165/rcmb.2018-0313oc
Autor:
Peter B. Dirks, Kenneth G. Geles, Bin-Bing S. Zhou, Justin C. Grindley, Marc Damelin, Haiying Zhang
Publikováno v:
Nature Reviews Drug Discovery. 8:806-823
The hypothesis that cancer is driven by tumour-initiating cells (popularly known as cancer stem cells) has recently attracted a great deal of attention, owing to the promise of a novel cellular target for the treatment of haematopoietic and solid mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc12b3bda7e9f2509f0ae4c958018613
https://doi.org/10.1038/nrd2137
https://doi.org/10.1038/nrd2137
Autor:
Joshua P. Wunderlich, Linheng Li, Mark Hembree, Yucai Xie, Kathryn P. Wagner, Glenn L. Radice, Jason Ross, Jeffrey S. Haug, Ruihong Zhu, Karin Gaudenz, John M. Perry, Erin P. Redenbaugh, Ariel Paulson, Tong Yin, Xi C. He, Christopher Seidel, Justin C. Grindley
Publikováno v:
Cell Stem Cell. 2:367-379
Within the bone marrow, three hematopoietic stem cell niches have been identified; the osteoblastic niche (Arai et al., 2004; Calvi et al., 2003; Nilsson et al., 2001; Zhang et al., 2003), the vascular niche (Kiel et al., 2005), and the CAR cell nich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d180e127ffed51469c5b81185e3f57
https://doi.org/10.1016/j.stem.2008.01.017
https://doi.org/10.1016/j.stem.2008.01.017
Autor:
Qiang Tian, Leroy Hood, Terrence A. Barrett, Leanne M. Wiedemann, Tong Yin, Mark Hembree, Hong Wu, Teri Johnson, Raminarao Dirisina, Kimberly S. Porter-Westpfahl, Linheng Li, Xi C. He, Toshiro Sato, W. Andy Tao, Justin C. Grindley
Publikováno v:
Nature Genetics. 39:189-198
Intestinal polyposis, a precancerous neoplasia, results primarily from an abnormal increase in the number of crypts, which contain intestinal stem cells (ISCs). In mice, widespread deletion of the tumor suppressor Phosphatase and tensin homolog (PTEN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40155f8303827ef6f3ababe1a44439d4
https://doi.org/10.1038/ng1928
https://doi.org/10.1038/ng1928
Autor:
Miriam P. Zidehsarai, Justin C. Grindley, Veronica J. Roberts, Sara Barth-Hall, Cornelia A. Bentley, Parlow Af
Publikováno v:
Endocrine. 10:171-178
Pax6, an evolutionarily conserved transcription factor, is expressed in the murine and zebrafish embryonic pituitary, but its role in pituitary development and endocrine function has not been described. To study the role of Pax6 in vivo, we examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9349c4e8d0d00db77ee33f00984a5c7c
https://doi.org/10.1385/endo:10:2:171
https://doi.org/10.1385/endo:10:2:171
Publikováno v:
Mechanisms of Development. 64(1-2):111-126
Pax6 expression in the diencephalon of the mouse embryo is restricted both antero-posteriorly and dorso-ventrally, with changes in level occurring at prosomere boundaries. Small eye (Pax6Sey-1Neu) mice homozygous for Pax6 mutations have multiple defe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd18887fb5692b9dd772b60c2b86a956
Publikováno v:
Development. 124:1433-1441
Small eye (Sey) mice homozygous for mutations in the Pax-6 gene have no lenses and no nasal cavities. We have examined the ontogeny of eye and nasal defects in Sey/Sey embryos and have related the defects seen to the pattern of Pax-6 mRNA expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d0ee019bce318ea349645c5d234288
https://doi.org/10.1242/dev.124.8.1433
https://doi.org/10.1242/dev.124.8.1433
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 62:249-256
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d8841fa6ce9a369d3b7529b35abfbd3
https://doi.org/10.1101/sqb.1997.062.01.031
https://doi.org/10.1101/sqb.1997.062.01.031
Autor:
Ryohichi Sugimura, Linheng Li, Sheng Ding, Justin C. Grindley, Jeffrey S. Haug, John M. Perry, Xi C. He
Publikováno v:
Genesdevelopment. 25(18)
Although self-renewal is the central property of stem cells, the underlying mechanism remains inadequately defined. Using a hematopoietic stem and progenitor cell (HSPC)-specific conditional induction line, we generated a compound genetic model beari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1baa9ac704fe127673c5479415ce1b32
https://pubmed.ncbi.nlm.nih.gov/21890648
https://pubmed.ncbi.nlm.nih.gov/21890648
Autor:
Soraya Abbasi, S. Lee Adamson, Anne M. Ades, N. Scott Adzick, Kurt H. Albertine, Steven M. Altschuler, Ruben E. Alvaro, Russell V. Anthony, Shankari Arulkumaran, Richard L. Auten, Mary Ellen Avery, Ellis D. Avner, H. Scott Baldwin, Philip L. Ballard, Eduardo Bancalari, David J.P. Barker, Damien Bates, Frederick C. Battaglia, †Karl Bauer, Gary K. Beauchamp, Corinne Benchimol, Laura Bennet, Phillip R. Bennett, Robert A. Berg, Melvin Berger, Monica Bhatia, Vinod K. Bhutani, Stan R. Blecher, Arlin B. Blood, David L. Bolender, Rada Boskovic, Robert D.H. Boyd, Robert A. Brace, Eileen D. Brewer, Delma L. Broussard, Laura D. Brown, Douglas G. Burrin, Bridgette M.P. Byrne, Anne Grete Byskov, Mitchell S. Cairo, Barbara Cannon, Michael Caplan, Luke C. Carey, Susan E. Carlson, David P. Carlton, William J. Cashore, Yang Chai, Carol L. Cheatham, Sylvain Chemtob, Robert L. Chevalier, Sadhana Chheda, Robert D. Christensen, David H. Chu, Robert Ryan Clancy, M. Thomas Clandinin, David A. Clark, Jane Cleary-Goldman, Ronald I. Clyman, Susan S. Cohen, John Colombo, Howard E. Corey, Robert B. Cotton, Beverly J. Cowart, Richard M. Cowett, Leona Cuttler, Mary E. D’Alton, Enrico Danzer, Elmer S. David, Diva D. De León, Maria Delivoria-Papadopoulos, Raye-Ann Odegaard deRegnier, Thomas G. Diacovo, George A. Diaz, Chris J. Dickinson, John P. Dormans, Kerry McGarr Empey, Offer Erez, Robert P. Erickson, Bulent Erol, Mohamed Abdelmonem Fahim, Leonard G. Feld, Miguel Feldman, Ronaldo P. Ferraris, Douglas G. Field, Delbert A. Fisher, Jennifer Frances, Hans-Georg Frank, Philippe S. Friedlich, Aaron L. Friedman, Joshua R. Friedman, Marianne Garland, Michael K. Georgieff, Peter D. Gluckman, Armond S. Goldman, Roberto Ariel Gomez, Francesca Gotsch, Denis M. Grant, Lucy R. Green, Adda Grimberg, Justin C. Grindley, Ian Gross, M. Brad Guffey, Jean-Pierre Guignard, Alistair Jan Gunn, Gabriel G. Haddad, J. Nathan Hagstrom, J. Nina Ham, Simon J. Hambidge, Margit Hamosh, Mark A. Hanson, Richard Harding, Olga T. Hardy, Mary Catherine Harris, Musa A. Haxhiu, William W. Hay, null Jr., William C. Heird, Emilio Herrera, Harry R. Hill, A. Craig Hillemeier, Kurt Hirschhorn, Steven B. Hoath, Stuart B. Hooper, Tracy E. Hunley, Shahid M. Husain, Susan M. Hutson, Machiko Ikegami, Terrie E. Inder, John Lynn Jefferies, Alan H. Jobe, Lois H. Johnson, Sonja E. Johnson, Michael V. Johnston, Richard B. Johnston, Deborah P. Jones, Peter Lloyd Jones, Rebecca L. Jones, Pedro A. Jose, Satish C. Kalhan, Suhas G. Kallapur, Stanley Kaplan, Heidi Eigenrauch Karpen, Saul J. Karpen, Sudha Kashyap, Frederick J. Kaskel, Lorraine E. Levitt Katz, Susan E. Keeney, Omar S. Khwaja, Laurie E. Kilpatrick, David Winston Kimberlin, John P. Kinsella, Jay K. Kolls, Valentina Kon, Ernest A. Kopecky, Gideon Koren, Nancy F. Krebs, Thomas J. Kulik, Juhi Kumar, Juan Pedro Kusanovic, Jessica Katz Kutikov, Timothy R. La Pine, Miguel Angel Lasunción, Tucker W. LeBien, Mary M. Lee, Matthew K. Lee, Fred Levine, Chris A. Liacouras, †Michael A. Linshaw, Steven Lobritto, Cynthia A. Loomis, Maria Luisa S. Sequeira Lopez, John M. Lorenz, Felicia M. Low, Ralph A. Lugo, Akhil Maheshwari, Shadi N. Malaeb, Carlos B. Mantilla, M. Michele Mariscalco, László Maródi, Karel Maršál, Richard J. Martin, Dwight E. Matthews, Alan N. Mayer, Jane E. McGowan, James L. McManaman, Tim C. McQuinn, Huseyin Mehmet, Julie A. Mennella, Martha J. Miller, Helen A. Mintz-Hittner, Paul Monagle, Iona M. Monteiro, Jacopo P. Mortola, Glen E. Mott, Maka Mshvildadze, M. Zulficar Mughal, Susan E. Mulroney, Upender K. Munshi, Leslie Myatt, Margaret Myers, Ran Namgung, Sumana Narasimhan, Heinz Nau, Jan Nedergaard, Josef Neu, Margaret Cobb Neville, Heber C. Nielsen, Lee Niswander, Lawrence M. Nogee, Shahab Noori, Victoria Fay Norwood, Luigi D. Notarangelo, Edward S. Ogata, Robin Kjerstin Ohls, Taher I. Omari, James F. Padbury, Mark R. Palmert, Prabhu S. Parimi, Elvira Parravicini, Gilberto R. Pereira, Jeffrey M. Perlman, Anthony F. Philipps, Arthur S. Pickoff, Grisha Pirianov, David Pleasure, Jeanette Pleasure, Sabine Luise Plonait, Daniel H. Polk, Scott L. Pomeroy, Fred Possmayer, Martin Post, Brandon S. Poterjoy, Gordon G. Power, Jorge A. Prada, Lawrence S. (Lance) Prince, Guy Putet, Theodore J. Pysher, Marlene Rabinovitch, Scott H. Randell, Timothy Robert Hume Regnault, Jann Rhodes, Michael J. Rieder, Henrique Rigatto, Natalie E Rintoul, Roberto Romero, Seamus A. Rooney, James C. Rose, Charles R. Rosenfeld, Arthur J. Ross, Colin D. Rudolph, Martin Rutter, Thor Willy Ruud-Hansen, Rakesh Sahni, Harvey B. Sarnat, Lisa M. Satlin, Ola Didrik Saugstad, Kurt R. Schibler, Frank C. Schmalstieg, Karl Schulze, Jeffrey Schwartz, Gunnar Sedin, Jeffrey L. Segar, Istvan Seri, Thomas H. Shaffer, Philip W. Shaul, Jayant P. Shenai, Colin P. Sibley, Gary C. Sieck, Theresa M. Siler-Khodr, Rebecca Anne Simmons, Emidio M. Sivieri, Harold C. Slavkin, Brian S. Snarr, Evan Y. Snyder, Jeanne M. Snyder, Martha Sola-Visner, Michael J. Solhaug, Charles A. Stanley, F. Bruder Stapleton, Barbara S. Stonestreet, Dennis M. Styne, William E. Sweeney, Deanna T. Taylor, Paul S. Thornton, Jeffrey A. Towbin, William E. Truog, Reginald C. Tsang, Nicole Ullrich, Edi Vaisbuch, John E. Van Aerde, Carmella van de Ven, Johannes (Hans) B. van Goudoever, Minke Van Tuyl, Robert C. Vannucci, Susan J. Vannucci, Matteo Vatta, Daniela Virgintino, Joseph J. Volpe, MaryAnn V. Volpe, Reidar Wallin, David Warburton, Robert M. Ward, Kristi L. Watterberg, Steven L. Werlin, Lynne A. Werner, Susan E. Wert, Andy Wessels, †Lars Grabow Westergaard, Jeffrey A. Whitsett, Michaelann S. Wilke, Louise Wilkins-Haug, †Dermot H. Williamson, Craig B. Woda, Douglas A. Woelkers, Marla R. Wolfson, Robert P. Woroniecki, Stephen Yip, Mervin C. Yoder, Stephen L. Young, Dan Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52b4a87081be2b30749f95790464899a
https://doi.org/10.1016/b978-1-4160-3479-7.10200-9
https://doi.org/10.1016/b978-1-4160-3479-7.10200-9
