Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Justin C Hope"'
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1427 (2008)
The protein kinase Chk1 is an essential component of the DNA damage checkpoint pathway. Chk1 is phosphorylated and activated in the fission yeast Schizosaccharomyces pombe when cells are exposed to agents that damage DNA. Phosphorylation, kinase acti
Externí odkaz:
https://doaj.org/article/c738b9c06d4c4ab1a63e29c7daf8c8b0
Publikováno v:
Nucleic Acids Research. 30:4781-4792
Our interest in the Schizosaccharomyces pombe RecQ helicase, rqh1+, led us to investigate the function of a related putative DNA helicase, srs2+. We identified the srs2+ homolog in S.pombe, and found that srs2+ is not essential for cell viability. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acad8ef5314eab323facd54297a930d2
https://doi.org/10.1093/nar/gkf581
https://doi.org/10.1093/nar/gkf581
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1427 (2008)
PLoS ONE
PLoS ONE
Background The protein kinase Chk1 is an essential component of the DNA damage checkpoint pathway. Chk1 is phosphorylated and activated in the fission yeast Schizosaccharomyces pombe when cells are exposed to agents that damage DNA. Phosphorylation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f49a4469bce8bf589dbbd6ede22ad4
http://europepmc.org/articles/PMC2173936?pdf=render
http://europepmc.org/articles/PMC2173936?pdf=render
Autor:
Jun Mitsumoto, Greg A. Freyer, Mohamed Maftahi, Lissette Delgado Cruzata, Justin C. Hope, Amit Duvshani
Publikováno v:
Molecular and cellular biology. 27(10)
During meiosis, double-strand breaks (DSBs) lead to crossovers, thought to arise from the resolution of double Holliday junctions (HJs) by an HJ resolvase. In Schizosaccharomyces pombe, meiotic crossovers are produced primarily through a mechanism re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87589c85c61be772a3629d3a730c2a8d
https://pubmed.ncbi.nlm.nih.gov/17353272
https://pubmed.ncbi.nlm.nih.gov/17353272
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 103(15)
Many questions remain about the process of DNA double strand break (DSB) repair by homologous recombination (HR), particularly concerning the exact function played by individual proteins and the details of specific steps in this process. Some recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2beffe50e08a59977b33abc5f63505
https://pubmed.ncbi.nlm.nih.gov/16595622
https://pubmed.ncbi.nlm.nih.gov/16595622
Following replication arrest, multiple cellular responses are triggered to maintain genomic integrity. In fission yeast, the RecQ helicase, Rqh1, plays a critical role in this process. This is demonstrated in Δrqh1 cells that, following treatment wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85256a52faf58ba08bf52cac99034fdc
https://europepmc.org/articles/PMC1450410/
https://europepmc.org/articles/PMC1450410/
