Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Justin Burdge"'
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100322- (2021)
Summary: Mouse models are essential for studying pain neurobiology and testing pain therapeutics. The reliance on assays that only measure the presence, absence, or frequency of a reflex have limited the reliability of preclinical pain studies. Our h
Externí odkaz:
https://doaj.org/article/16bb9289b4f5455ca0f5c9545da36169
Autor:
Jessica M Jones, William Foster, Colin R Twomey, Justin Burdge, Osama M Ahmed, Talmo D Pereira, Jessica A Wojick, Gregory Corder, Joshua B Plotkin, Ishmail Abdus-Saboor
Publikováno v:
eLife, Vol 9 (2020)
Objective and automatic measurement of pain in mice remains a barrier for discovery in neuroscience. Here, we capture paw kinematics during pain behavior in mice with high-speed videography and automated paw tracking with machine and deep learning ap
Externí odkaz:
https://doaj.org/article/3a49d12c9d99401093221c535e3034d8
Autor:
William Olson, Ishmail Abdus-Saboor, Lian Cui, Justin Burdge, Tobias Raabe, Minghong Ma, Wenqin Luo
Publikováno v:
eLife, Vol 6 (2017)
The human distal limbs have a high spatial acuity for noxious stimuli but a low density of pain-sensing neurites. To elucidate mechanisms underlying regional differences in processing nociception, we sparsely traced non-peptidergic nociceptors across
Externí odkaz:
https://doaj.org/article/8a0b7cb3ed614470913456b3f8ba2292
Publikováno v:
Neuron
Breathing can be heavily influenced by pain or internal emotional states, but the neural circuitry underlying this tight coordination is unknown. Here we report that Oprm1 (μ-opioid receptor)-expressing neurons in the lateral parabrachial nucleus (P
Autor:
Osama M. Ahmed, Jessica A. Wojick, Joshua B. Plotkin, Gregory Corder, Jessica M Jones, Ishmail Abdus-Saboor, Talmo D. Pereira, William R. Foster, Justin Burdge, Colin R. Twomey
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Objective and automatic measurement of pain in mice remains a barrier for discovery in neuroscience. Here, we capture paw kinematics during pain behavior in mice with high-speed videography and automated paw tracking with machine and deep learning ap
Autor:
Talmo D. Pereira, Colin R. Twomey, Osama M. Ahmed, Jessica A. Wojick, Gregory Corder, William R. Foster, Ishmail Abdus-Saboor, Joshua B. Plotkin, Justin Burdge, Jessica M Jones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd19c78e9f343c557c18ef11b08a9459
https://doi.org/10.7554/elife.57258.sa2
https://doi.org/10.7554/elife.57258.sa2
Autor:
Colin R. Twomey, Osama M. Ahmed, William R. Foster, Justin Burdge, Ishmail Abdus-Saboor, Joshua B. Plotkin, Jessica A. Wojick, Gregory Corder, Jessica M Jones
Objective and automatic measurement of pain in mice remains a barrier for discovery in both basic and translational neuroscience. Here we capture rapid paw kinematics during pain behavior in mice with high-speed videography and automated paw tracking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4a479396b6a12780fe905dcdd724a0
https://doi.org/10.1101/2020.02.18.955070
https://doi.org/10.1101/2020.02.18.955070
Autor:
Tobias Raabe, Wenqin Luo, Lian Cui, William Olson, Ishmail Abdus-Saboor, Minghong Ma, Justin Burdge
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
The human distal limbs have a high spatial acuity for noxious stimuli but a low density of pain-sensing neurites. To elucidate mechanisms underlying the ‘pain fovea’, we sparsely traced non-peptidergic nociceptors across the body using a newly ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20bbaff3763bcbc5a10fb1aafdf7828
Autor:
Weihua Cai, Mark Lay, Yuan Xiang Tao, Xinying Guo, Justin Burdge, John R. Bethea, Jessica M Jones, Xinzhong Dong, Roman Fischer, Ishmail Abdus-Saboor, Wenqin Luo, Long Ding, Minghong Ma, Peter Dong, Nathan T. Fried, Kathryn A Swanson
Publikováno v:
Cell reports
SUMMARY Rodents are the main model systems for pain research, but determining their pain state is challenging. To develop an objective method to assess pain sensation in mice, we adopt high-speed videography to capture sub-second behavioral features