Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Justin Brathwaite"'
Publikováno v:
مجله كليه طب الكندي, Vol 19, Iss 2 (2023)
In the United States, the pharmaceutical industry is actively devising strategies to improve the diversity of clinical trial participants. These efforts stem from a plethora of evidence indicating that various ethnic groups respond differently to a g
Externí odkaz:
https://doaj.org/article/baf73b69d4fa441188c647ef4e4fe38c
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-8 (2018)
Chad Smith et al. show that dietary polyphenols, compounds found in grapes, enable mice to remember fearful events more effectively and map this function to the hippocampal dentate gyrus neurons. This study offers a way to identify the cellular subpo
Externí odkaz:
https://doaj.org/article/2ccce6fe39fc4ddf945495be7483a919
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Neurodegenerative disorders constitute a group of multifaceted conditions characterized by the progressive loss of neurons and synaptic connections consequent to a combination of specific genetic predispositions and stochastic stressors. The neuropat
Externí odkaz:
https://doaj.org/article/f35020841afe48eb82a2187ebe87247f
Autor:
Tal Frolinger, Mayumi Tsuji, Thomas E. Lloyd, Jeremiah J. Faith, Ke Hao, Steven Sims, Lap Ho, Eileen Carry, Susan Westfall, Danyue Zhao, Justin Brathwaite, Qingli Wu, James E. Simon, Giulio Maria Pasinetti, Kenjiro Ono, Ilaria Mogno, Kai Ruan, Paolo Mazzola
Publikováno v:
The Journal of Nutritional Biochemistry. 64:170-181
The intestinal microbiota actively converts dietary flavanols into phenolic acids, some of which are bioavailable in vivo and may promote resilience to select neurological disorders by interfering with key pathologic mechanisms. Since every person ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ea6f867d5705e74d1671176c9db958
https://doi.org/10.1016/j.jnutbio.2018.10.019
https://doi.org/10.1016/j.jnutbio.2018.10.019
Autor:
Qingli Wu, James E. Simon, Kyle J. Trageser, Danyue Zhao, Jun Wang, Justin Brathwaite, Zahra Jlayer, Chad C. Smith, Adelaida Esteban-Fernández, Giulio Maria Pasinetti, Simoni Tiano, Bo Yuan
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 10, Iss 1, Pp 1-11 (2020)
Translational Psychiatry, Vol 10, Iss 1, Pp 1-11 (2020)
Major depressive disorder (MDD) is a leading cause of disability, and there is an urgent need for new therapeutics. Stress-mediated induction of pro-inflammation in the periphery contributes to depression-like behaviors both in humans and in experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f383d4c1bcd5e03b61653c075de2194a
https://doi.org/10.1038/s41398-020-0859-x
https://doi.org/10.1038/s41398-020-0859-x
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-8 (2018)
Grape-derived polyphenols have been investigated for their role in promoting memory in model systems of stress, but little is known about select subpopulations of neurons that are influenced by polyphenols to improve memory performance. Granule neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0383db4b4c31675846a21bd754e0887
https://doaj.org/article/2ccce6fe39fc4ddf945495be7483a919
https://doaj.org/article/2ccce6fe39fc4ddf945495be7483a919
Autor:
Tal Frolinger, Jing Huang, Giulio Maria Pasinetti, Justin Brathwaite, Steven Sims, Carmen Freire Cobo, Chad Smith, Sterre de Boer
Publikováno v:
Frolinger, T, Smith, C, Cobo, C F, Sims, S, Brathwaite, J, de Boer, S, Huang, J & Pasinetti, G M 2018, ' Dietary polyphenols promote resilience against sleep deprivation-induced cognitive impairment by activating protein translation ', FASEB Journal, vol. 32, no. 10, pp. 539-5404 . https://doi.org/10.1096/fj.201800030R
FASEB Journal, 32(10), 539-5404. FASEB
FASEB Journal, 32(10), 539-5404. FASEB
Previous evidence has suggested that dietary supplementation with a bioactive dietary polyphenol preparation (BDPP) rescues impairment of hippocampus-dependent memory in a mouse model of sleep deprivation (SD). In the current study, we extend our pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6cb23b231afb30da984f61636177bc
https://doi.org/10.1096/fj.201800030r
https://doi.org/10.1096/fj.201800030r
Autor:
Gregory A. Elder, Libby Ward, Jun Wang, Mihaly Mezei, Justin Brathwaite, Roberto Sanchez, Lap Ho, Weina Bi, Giulio Maria Pasinetti, Paolo Mazzola, Wei Zhao, Shrishailam Yemul, Daniel Freire
Publikováno v:
Journal of Cellular Biochemistry. 117:2241-2248
The objective of this study was to develop an in silico screening model for characterization of potential novel ligands from commercial drug libraries able to functionally activate certain olfactory receptors (ORs), which are members of the class A r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53fa4ee981073417f5ade0fc969fddbc
https://doi.org/10.1002/jcb.25521
https://doi.org/10.1002/jcb.25521
Autor:
Valentina Broggini, Libby Ward, Paolo Mazzola, Alessandra Anzuini, Giulio Maria Pasinetti, Giorgio Annoni, Giuseppe Bellelli, Justin Brathwaite, Breanna Valcarcel, Sara Zazzetta
OBJECTIVES: To determine whether poor nutritional status can predict postoperative delirium in elderly adults undergoing hip fracture surgery. DESIGN: Prospective observational cohort study. SETTING: Italian orthogeriatric unit. PARTICIPANTS: Individ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3972198c1895d35fcc32b3feb2738bac
http://hdl.handle.net/10281/147959
http://hdl.handle.net/10281/147959
