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pro vyhledávání: '"Justin Bourret"'
Autor:
Masaru Ken Shiratori, Eric Fallon, Justin Bourret, Steven J. Meier, Salim Charaniya, Mahalia Corrales, Robert Kiss, Michael Pohlscheidt, Fikret Kulenovic
Publikováno v:
Applied Microbiology and Biotechnology. 98:2965-2971
The production of therapeutic proteins by mammalian cell culture is complex and sets high requirements for process, facility, and equipment design, as well as rigorous regulatory and quality standards. One particular point of concern and significant
Publikováno v:
Biotechnology and Bioengineering. 109:962-970
As the therapeutic monoclonal antibody (mAb) market continues to grow, optimizing production processes is becoming more critical in improving efficiencies and reducing cost-of-goods in large-scale production. With the recent trends of increasing cell
Publikováno v:
Journal of chromatography. A. 1218(31)
In this report, we have demonstrated the isolation and enrichment of charge variants of a monoclonal antibody IgG1 using cation exchange displacement chromatography. We successfully achieved the separation of acidic, main and basic charge variants wi