Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Justin B. Perry"'
Autor:
Shelby E. Hamm, Daniel D. Fathalikhani, Katherine E. Bukovec, Adele K. Addington, Haiyan Zhang, Justin B. Perry, Ryan P. McMillan, Michael W. Lawlor, Mariah J. Prom, Mark A. Vanden Avond, Suresh N. Kumar, Kirsten E. Coleman, J.B. Dupont, David L. Mack, David A. Brown, Carl A. Morris, J. Patrick Gonzalez, Robert W. Grange
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 144-160 (2021)
We tested the hypothesis that voluntary wheel running would complement microdystrophin gene therapy to improve muscle function in young mdx mice, a model of Duchenne muscular dystrophy. mdx mice injected with a single dose of AAV9-CK8-microdystrophin
Externí odkaz:
https://doaj.org/article/d1cbb7f0e57f48a4854b84e1f8896a3a
Autor:
Joseph P. Grieco, Mitchell E. Allen, Justin B. Perry, Yao Wang, Yipei Song, Ali Rohani, Stephanie L. E. Compton, James W. Smyth, Nathan S. Swami, David A. Brown, Eva M. Schmelz
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Ovarian cancer is the deadliest gynecological cancer in women, with a survival rate of less than 30% when the cancer has spread throughout the peritoneal cavity. Aggregation of cancer cells increases their viability and metastatic potential; however,
Externí odkaz:
https://doaj.org/article/6f3b4f33d1314b03ade033b4aa5cf565
Autor:
Dylan K. McDaniel, Veronica M. Ringel-Scaia, Holly A. Morrison, Sheryl Coutermarsh-Ott, McAlister Council-Troche, Jonathan W. Angle, Justin B. Perry, Grace Davis, Weinan Leng, Valerie Minarchick, Yi Yang, Bo Chen, Sky W. Reece, David A. Brown, Thomas E. Cecere, Jared M. Brown, Kymberly M. Gowdy, Michael F. Hochella, Irving C. Allen
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Coal is one of the most abundant and economic sources for global energy production. However, the burning of coal is widely recognized as a significant contributor to atmospheric particulate matter linked to deleterious respiratory impacts. Recently,
Externí odkaz:
https://doaj.org/article/46bb78bbc739413797c16110355f1999
Autor:
David Brown, Lifu Zhao, Justin B. Perry, Rodrigue Rossignol, Nivea Dias Amoedo, Wangde Dai, Bruno Le Grand, Juan Carreno, Robert A. Kloner, Aurelie Boucard
Publikováno v:
Cardiovascular Drugs and Therapy
Cardiovascular Drugs and Therapy, Springer Verlag, 2021, ⟨10.1007/s10557-020-07113-7⟩
Cardiovascular Drugs and Therapy, Springer Verlag, 2021, ⟨10.1007/s10557-020-07113-7⟩
Purpose : The present study was to determine whether OP2113 could limit myocardial infarction size and the no-reflow phenomenon in a rat myocardial ischemia/reperfusion model. Methods : Rat heart–isolated mitochondria (RHM) were used to investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533e7bb530b792ac55b79c02051f3369
https://doi.org/10.1007/s10557-020-07113-7
https://doi.org/10.1007/s10557-020-07113-7
Autor:
Grahame K. Kidd, Edward Ross Pennington, Tristan B. Raisch, Fatiha Moukdar, Hetal D. Patel, Emily Benson, Justin B. Perry, Saame Raza Shaikh, Maija Dambrova, Marina Makrecka-Kuka, Sahil Dadoo, David Brown, Mitchell E. Allen, Steven Poelzing, Xianlin Han
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Communications Biology
Communications Biology
Mitochondrial dysfunction contributes to cardiac pathologies. Barriers to new therapies include an incomplete understanding of underlying molecular culprits and a lack of effective mitochondria-targeted medicines. Here, we test the hypothesis that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f1d29b791fb789511eea8ab30b184b
http://link.springer.com/article/10.1038/s42003-020-1101-3
http://link.springer.com/article/10.1038/s42003-020-1101-3
Autor:
David Brown, Marina Makrecka-Kuka, Grace N. Davis, Mitchell E. Allen, Saame Raza Shaikh, Maija Dambrova, Robert W. Grange, Justin B. Perry
Publikováno v:
Journal of Molecular and Cellular Cardiology. 135:160-171
Novel therapeutic strategies to treat mitochondrial deficiencies in acute coronary syndromes are needed. Complex I of the mitochondrial electron transport system is damaged following ischemia/reperfusion (I/R) injury. This disruption contributes to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ad30aafdb03e3d2c927cfdff61d731
https://doi.org/10.1016/j.yjmcc.2019.08.010
https://doi.org/10.1016/j.yjmcc.2019.08.010
Autor:
Justin B. Perry, David Brown, D. Ryan King, Gregory S. Hoeker, James W. Smyth, Rachel L Padget, Steven Poelzing
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Recent studies revealed that relatively small changes in perfusate sodium ([Na+](o)) composition significantly affect cardiac electrical conduction and stability in contraction arrested ex vivo Langendorff heart preparations before and during simulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb6f2273836f999764ce3b5aef3c3db
http://europepmc.org/articles/PMC7560862
http://europepmc.org/articles/PMC7560862
Autor:
Jean-Baptiste Dupont, Daniel D. Fathalikhani, Haiyan Zhang, Michael W. Lawlor, Justin B. Perry, Ryan P. McMillan, Shelby E. Hamm, Carl Morris, David Brown, J. Patrick Gonzalez, Robert W. Grange, Mark A. Vanden Avond, Katherine E. Bukovec, Kirsten E. Coleman, Suresh Kumar, David L. Mack, Mariah J. Prom, Adele K. Addington
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss, Pp 144-160 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss, Pp 460-(2021)
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss, Pp 144-160 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss, Pp 460-(2021)
We tested the hypothesis that voluntary wheel running would complement microdystrophin gene therapy to improve muscle function in young mdx mice, a model of Duchenne muscular dystrophy. mdx mice injected with a single dose of AAV9-CK8-microdystrophin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba057cbdb449dd60313d69fb46e5d116
https://pubmed.ncbi.nlm.nih.gov/34820472
https://pubmed.ncbi.nlm.nih.gov/34820472
Autor:
David Brown, Grace N. Davis, Rakesh K. Kapania, Abinash Padhi, Ryan P. McMillan, Justin B. Perry, Elizabeth N. Kaweesa, Amrinder S. Nain, Alexander H. Thomson, Sandra Loesgen
Publikováno v:
Am J Physiol Cell Physiol
Cell migration is centrally involved in a myriad of physiological processes, including morphogenesis, wound healing, tissue repair, and metastatic growth. The bioenergetics that underlie migratory behavior are not fully understood, in part because of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521fec3d0e3cf0b36b9b670f3eab0663
https://pubmed.ncbi.nlm.nih.gov/31875698
https://pubmed.ncbi.nlm.nih.gov/31875698
Autor:
Mihai Gheorghiade, Wilson S. Colucci, Justin B. Perry, Burkert Pieske, Gerasimos Filippatos, Stefan D. Anker, Bertram Pitt, Stephen J. Greene, Saame Raza Shaikh, Adriaan A. Voors, Javed Butler, Mitchell E. Allen, Brian L. Stauffer, David Brown, John G.F. Cleland, Hani N. Sabbah
Publikováno v:
Nature reviews cardiology, 14(4), 238-250. Nature Publishing Group
Nature reviews. Cardiology
Nature reviews. Cardiology
Heart failure is a pressing worldwide public-health problem with millions of patients having worsening heart failure. Despite all the available therapies, the condition carries a very poor prognosis. Existing therapies provide symptomatic and clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70acff3333eae1791d5adcfd759ca6c
https://doi.org/10.1038/nrcardio.2016.203
https://doi.org/10.1038/nrcardio.2016.203