Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Justin B. Morgenthaler"'
Autor:
Jennifer C. Passini, Erin M. Kamowski, Timothy D. Lash, Justin B. Morgenthaler, Brian E. Butkus, Alexandra M. Young, David L. Cedeño, Kevin A. Edwards, Marjorie A. Jones, Manuel H. Constantino, Steven J. Peters
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:7033-7038
Dimethyl and diethyl carbaporphyrin ketals inhibit the growth of Leishmania tarentolae promastigotes in vitro. The concentration dependency of the inhibitory effect was tested using the MTT assay. The presence of reactive oxygen species, such as sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e25eac7bc4d72ecee698e0e17095d29
https://doi.org/10.1016/j.bmc.2008.05.037
https://doi.org/10.1016/j.bmc.2008.05.037
Autor:
Marjorie A. Jones, Ahmed W. Jafri, Jon A. Friesen, Justin B. Morgenthaler, Jason R. Stephenson
Publikováno v:
American Journal of Biochemistry and Biotechnology. 4:442-449
The effects of covalent cross-linkers on the enzyme, coproporphyrinogen oxidase, had been previously studied but their role in protecting the enzyme from protease cleavage has not been evaluated. Therefore, we examined how the cross-linker bis (sulfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b97a50888856f617c7ef9557916b4f26
https://doi.org/10.3844/ajbbsp.2008.442.449
https://doi.org/10.3844/ajbbsp.2008.442.449
Autor:
Justin B. Morgenthaler, Julie A. Stacey, Marjorie A. Jones, Jon A. Friesen, Timothy D. Lash, Jason R. Stephenson
Publikováno v:
Protein Science. 16:401-410
Coproporphyrinogen oxidase (CPO) is the sixth enzyme in the heme biosynthetic pathway, catalyzing two sequential oxidative decarboxylations of propionate moieties on coproporphyrinogen-III forming protoporphyrinogen-IX through a monovinyl intermediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb836a6f84ae061bb79d57a7ac34506
https://doi.org/10.1110/ps.062636907
https://doi.org/10.1110/ps.062636907
Publikováno v:
Medical science monitor : international medical journal of experimental and clinical research. 14(1)
Defects in the enzyme coproporphyrinogen oxidase result in accumulation of porphyrins which may affect the severity of a subset of porphyrias. Thus evaluation of this enzyme for substrate selectivity is of value. Kinetic evaluations of recombinant hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2475f19b94720b48b54db242d2e3c242
https://pubmed.ncbi.nlm.nih.gov/18160932
https://pubmed.ncbi.nlm.nih.gov/18160932
Publikováno v:
The FASEB Journal. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2af334e96f47db8327e70dc951f829b2
https://doi.org/10.1096/fasebj.20.4.a45
https://doi.org/10.1096/fasebj.20.4.a45
Publikováno v:
American Journal of Biochemistry and Biotechnology. 2:146-147
A rapid, inexpensive and sensitive alternative to the traditional Western Blot is presented here. This method is very useful for detection of recombinant 6-his tagged proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c41de8e6c51757cfcec33e1309d35a22
https://doi.org/10.3844/ajbbsp.2006.146.147
https://doi.org/10.3844/ajbbsp.2006.146.147