Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Justin B Callaway"'
Autor:
Justin B Callaway, Scott A Smith, Douglas G Widman, Karen P McKinnon, Frank Scholle, Gregory D Sempowski, Dirk P Dittmer, James E Crowe, Aravinda M de Silva, Jenny P-Y Ting
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136708 (2015)
Dengue virus is a major global health threat and can lead to life-threatening hemorrhagic complications due to immune activation and cytokine production. Cross-reactive antibodies to an earlier dengue virus infection are a recognized risk factor for
Externí odkaz:
https://doaj.org/article/ac6ca7d5c7a14dba88fc25b0cc34eb5a
Autor:
Irving C Allen, John D Lich, Janelle C Arthur, Corey M Jania, Reid A Roberts, Justin B Callaway, Stephen L Tilley, Jenny P-Y Ting
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30612 (2012)
Among the 22 members of the nucleotide binding-domain, leucine rich repeat-containing (NLR) family, less than half have been functionally characterized. Of those that have been well studied, most form caspase-1 activating inflammasomes. NLRP12 is a u
Externí odkaz:
https://doaj.org/article/bea205d7c96a4f2e9bd4603e6663f63b
Autor:
Mike Scurria, Justin B. Callaway, Dan Lazar, Jenny P.-Y. Ting, James J. Cali, Martha O'brien, Tim Ugo, Gabriel Núñez, Raúl Muñoz-Planillo, Danielle Moehring, Laurent Bernad
Publikováno v:
Journal of Immunological Methods. 447:1-13
Inflammasomes are protein complexes induced by diverse inflammatory stimuli that activate caspase-1, resulting in the processing and release of cytokines, IL-1�� and IL-18, and pyroptosis, an immunogenic form of cell death. To provide a homogeneo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45132b55a9ca852597fb30841ecafcb0
https://doi.org/10.1016/j.jim.2017.03.004
https://doi.org/10.1016/j.jim.2017.03.004
Publikováno v:
Nature Medicine. 21:677-687
The inflammasomes are innate immune system receptors and sensors that regulate the activation of caspase-1 and induce inflammation in response to infectious microbes and molecules derived from host proteins. They have been implicated in a host of inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a929a8417d5cf9815a45ecbf18b012a0
https://doi.org/10.1038/nm.3893
https://doi.org/10.1038/nm.3893
Autor:
Jenny P.-Y. Ting, Scott A. Smith, Aravinda M. de Silva, Justin B. Callaway, James E. Crowe, Karen P. McKinnon
Publikováno v:
The Journal of biological chemistry. 290(28)
Approximately 500,000 people are hospitalized with severe dengue illness annually. Antibody-dependent enhancement (ADE) of dengue virus (DENV) infection is believed to contribute to the pathogenic cytokine storm described in severe dengue patients, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163a31c438ba7e9078444ed432ed4510
https://pubmed.ncbi.nlm.nih.gov/26032420
https://pubmed.ncbi.nlm.nih.gov/26032420
Autor:
Jenny P.-Y. Ting, Haitao Wen, Joseph A. Duncan, Justin B. Callaway, Elizabeth Holley-Guthrie, Tim K. Eitas, Peter Broglie, Karen V. Swanson, Max Tze Han Huang, Debra J. Taxman
The interleukin (IL)-1β-processing inflammasome has recently been identified as a target for pathogenic evasion of the inflammatory response by a number of bacteria and viruses. We postulated that the periodontal pathogen, Porphyromonas gingivalis m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d55e762ae7e45bc93c029afd4f087d4
https://europepmc.org/articles/PMC3463344/
https://europepmc.org/articles/PMC3463344/
Autor:
Janelle C. Arthur, Reid A. Roberts, John D. Lich, Corey M. Jania, Irving C. Allen, Justin B. Callaway, Stephen L. Tilley, Jenny P.-Y. Ting
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30612 (2012)
PLoS ONE
PLoS ONE
Among the 22 members of the nucleotide binding-domain, leucine rich repeat-containing (NLR) family, less than half have been functionally characterized. Of those that have been well studied, most form caspase-1 activating inflammasomes. NLRP12 is a u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975f5393321109a94fadded927719fe2
http://europepmc.org/articles/PMC3264608?pdf=render
http://europepmc.org/articles/PMC3264608?pdf=render
Autor:
Jenny P.-Y. Ting, Frank Scholle, Karen P. McKinnon, Dirk P. Dittmer, Aravinda M. de Silva, James E. Crowe, Gregory D. Sempowski, Scott A. Smith, Douglas G. Widman, Justin B. Callaway
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 8, p e0136708 (2015)
PLoS ONE, Vol 10, Iss 8, p e0136708 (2015)
Dengue virus is a major global health threat and can lead to life-threatening hemorrhagic complications due to immune activation and cytokine production. Cross-reactive antibodies to an earlier dengue virus infection are a recognized risk factor for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8bcbc0292720c7042b94752129f9f23
https://doi.org/10.1371/journal.pone.0136708
https://doi.org/10.1371/journal.pone.0136708
Autor:
Raúl Muñoz-Planillo, Danielle Moehring, James J. Cali, Justin B. Callaway, Laurent Bernad, Mike Scurria, Jenny P.-Y. Ting, Dan Lazar, Martha O'brien, Tim Ugo, Gabriel Núñez
Publikováno v:
Cancer Research. 75:1319-1319
Inflammatory responses and immune modulation play important and complex roles in cancer development and therapy, but methods to monitor caspase-1 activity associated with inflammasome activation have been limited. Inflammasomes are protein complexes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12cf9454ca7201e0660a6e54230e93ec
https://doi.org/10.1158/1538-7445.am2015-1319
https://doi.org/10.1158/1538-7445.am2015-1319