Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Justin A MacDonald"'
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226406 (2019)
Myosin regulatory light chain (LC20) phosphorylation plays an important role in vascular smooth muscle contraction and cell migration. Ca2+/calmodulin-dependent myosin light chain kinase (MLCK) phosphorylates LC20 (its only known substrate) exclusive
Externí odkaz:
https://doaj.org/article/33ab482af2a14cec9dcc273dfdbf362b
Autor:
Ashleigh Hansen, Laurie Alston, Sarah E Tulk, L Patrick Schenck, Michael E Grassie, Basmah F Alhassan, Arun Teja Veermalla, Samir Al-Bashir, Fernand-Pierre Gendron, Christophe Altier, Justin A MacDonald, Paul L Beck, Simon A Hirota
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81491 (2013)
C. difficile is a Gram-positive spore-forming anaerobic bacterium that is the leading cause of nosocomial diarrhea in the developed world. The pathogenesis of C. difficile infections (CDI) is driven by toxin A (TcdA) and toxin B (TcdB), secreted fact
Externí odkaz:
https://doaj.org/article/516d7b754c8841ef94766d33ae22596f
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50007 (2012)
We investigated the effects of collective or individual self-construal priming on recall in a short-term memory (STM) task. We primed participants to either their individual or their collective self-construals or a neutral control condition. Particip
Externí odkaz:
https://doaj.org/article/4115465ac83b43f7a8568e4e0641862e
Autor:
Sara R. Turner, Abdulhameed Al‐Ghabkari, David A. Carlson, Mona Chappellaz, Cindy Sutherland, Timothy A. J. Haystead, William C. Cole, Justin A. MacDonald
Publikováno v:
Experimental Physiology, Vol 108, Iss 7, Pp 986-997 (2023)
Abstract The vascular smooth muscle (VSM) of resistance blood vessels is a target of intrinsic autoregulatory responses to increased intraluminal pressure, the myogenic response. In the brain, the myogenic reactivity of cerebral arteries is critical
Externí odkaz:
https://doaj.org/article/c8e96dfe37be4ac3bc4b558c848ca3ff
Autor:
Yang Yang, Biao Ma, Mahbod Djamshidi, Qingrun Zhang, Anusi Sarkar, Ayan Chanda, Uyen Tran, Jung Soh, Christina Sandall, Huey-Miin Chen, Justin A. MacDonald, Shirin Bonni, Christoph W. Sensen, Jianhua Zheng, Karl Riabowol
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 3, Pp 151341- (2023)
ING1 is a chromatin targeting subunit of the Sin3a histone deacetylase (HDAC) complex that alters chromatin structure to subsequently regulate gene expression. We find that ING1 knockdown increases expression of Twist1, Zeb 1&2, Snai1, Bmi1 and TSHZ1
Externí odkaz:
https://doaj.org/article/1436a51a89e047f3b13b738b31e903d7
Smoothelin-like 1 knockout mice display sex-dependent alterations in blood flow and cardiac function
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 101:27-40
Smoothelin-like 1 (SMTNL1) modulates the contractile performance of smooth muscle and thus has a key role in vascular homeostasis. Elevated vascular tone, recognized as a contributor to the development of progressive cardiac dysfunction, was previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d485a5e039cdbab594065dec357e55f
https://doi.org/10.1139/cjpp-2022-0172
https://doi.org/10.1139/cjpp-2022-0172
The inflammasome-forming NOD-like receptor containing pyrin-3 (NLRP3) protein is a critical player in the innate immune responses to cellular danger signals. New structural data of NLRP3 provide a framework to probe the conformational impact of nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91599fe5b3e44018dd4c49cdd36453ab
https://doi.org/10.1101/2023.05.03.539258
https://doi.org/10.1101/2023.05.03.539258
Autor:
Kyle M. Jensen, Justin A. MacDonald
Publikováno v:
PsychophysiologyREFERENCES.
In the field of EEG, researchers generally rely on rules of thumb, rather than a priori statistical calculations, when planning the number of trials to include in an ERP study. To aid in this practice, studies have tried to establish minimum numbers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6de1d97595c71136c9ebeef175a53a9
https://pubmed.ncbi.nlm.nih.gov/36577739
https://pubmed.ncbi.nlm.nih.gov/36577739
Autor:
Sara R. Turner, David A. Carlson, Mona Chappellaz, Cindy Sutherland, Timothy A.J. Haystead, William C. Cole, Justin A. MacDonald
The vascular smooth muscle (VSM) of resistance blood vessels displays intrinsic autoregulatory responses to increased intraluminal pressure, the myogenic response. In the brain, the myogenic responses of cerebral arterioles are critical to homeostati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff8b01e52ac963e63637ca0261ca8fd
https://doi.org/10.1101/2022.06.10.495652
https://doi.org/10.1101/2022.06.10.495652
Publikováno v:
Pharmaceuticals, Vol 3, Iss 6, Pp 1739-1760 (2010)
Smooth muscle is a major component of most hollow organ systems (e.g., airways, vasculature, bladder and gut/gastrointestine); therefore, the coordinated regulation of contraction is a key property of smooth muscle. When smooth muscle functions norma
Externí odkaz:
https://doaj.org/article/7666ef4674b04fa3ac44743621927856