Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Justin R. Denton"'
Publikováno v:
Analytical Methods. 8:4659-4663
2-Chloromalonaldehyde (2-ClMA) is utilized in the pharmaceutical sector as a reagent to form thiazole heterocycles which can be further functionalized. This present work describes a hydrophilic interaction chromatography (HILIC) strategy for the trac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c304269281f2567e3b3d14845919015
https://doi.org/10.1039/c6ay01257d
https://doi.org/10.1039/c6ay01257d
Publikováno v:
Journal of Chromatography & Separation Techniques.
Control of regioisomer impurities within pharmaceutical raw materials, intermediates, and active pharmaceutical ingredients are of major concern for the pharmaceutical industry. If regioisomer impurities are possible, their detection and quantitation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::141f049d8a08f64230af7f265b90f289
https://doi.org/10.4172/2157-7064.1000356
https://doi.org/10.4172/2157-7064.1000356
Publikováno v:
Anal. Methods. 6:6565-6570
The utilization of L-valine for its chiral centre is increasing in the fine chemical, biologic, and pharmaceutical sectors. Therefore, a simple and reliable chirality procedure is needed to assure that trace levels of D-valine are not present. The pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18cdc9f41385bbdd4a2f7283e9c0cfe5
https://doi.org/10.1039/c4ay01069h
https://doi.org/10.1039/c4ay01069h
Publikováno v:
Organic Letters. 13:4316-4319
A triple cascade process was developed for the rapid synthesis of polycyclic benzo-fused dihydrofurans. The first step is a rhodium-catalyzed cyclopropanation of α-aryldiazoketones with alkenes. This is followed by a silver-catalyzed ring expansion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bba64945b19db2100dff23fa7834aeb
https://doi.org/10.1021/ol2016548
https://doi.org/10.1021/ol2016548
Autor:
Justin R. Denton
Publikováno v:
Synthetic Communications. 41:770-776
A protocol has been developed to purify 9-(trifluoroacetyl)anthracene from anthracene, the major impurity associated in its synthesis. The protocol utilizes a chemoselective thermal Diels–Alder reaction, employing maleic anhydride as the dienophile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4a21cd8939d9fd0e806a1e03c8e6e70
https://doi.org/10.1080/00397911003668562
https://doi.org/10.1080/00397911003668562
Autor:
Justin R. Denton
Publikováno v:
Synthesis. 2010:775-782
Sulfonamide heterocycles, specifically 3-acylindoles, undergo a deprotection/alkylation sequence in the presence of an appropriate alcohol when cesium carbonate or potassium carbonate and a phase-transfer catalyst are utilized. The outcome of the one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc64001c9004232822b269e5d277821c
https://doi.org/10.1055/s-0029-1218627
https://doi.org/10.1055/s-0029-1218627
Publikováno v:
Synthesis. 2009:2840-2846
The synthesis of a silyl-protected derivative of 3-hydroxyvibsanin E has been achieved. The key step is a regio-and stereoselective C-H hydroxylation of an advanced tricyclic intermediate by means of a Rubottom oxidation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364d317d2328af4ed318e0b0e297a9b3
https://doi.org/10.1055/s-0029-1216912
https://doi.org/10.1055/s-0029-1216912
Autor:
Huw M. L. Davies, Justin R. Denton
Publikováno v:
Organic Letters. 11:787-790
The reaction of a variety of alpha-aryl-alpha-diazo ketones with activated olefins, catalyzed by the adamantyl glycine-derived dirhodium complex Rh(2)(S-PTAD)(4), generates cyclopropyl ketones with high diastereoselectivity (up to95:5 dr) and enantio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e40e71b4422dd7357315a9d04707e4
https://doi.org/10.1021/ol802614j
https://doi.org/10.1021/ol802614j
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 115
2-Hydroxypyridine-1-oxide (HOPO) is utilized in the pharmaceutical sector to facilitate the formation of amide bonds. This present work describes the development of a HPLC high pH ion-pairing method for the trace analysis of HOPO in pharmaceutically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acae8fc7b6e10cc9c40424835ca37fb
https://pubmed.ncbi.nlm.nih.gov/26163868
https://pubmed.ncbi.nlm.nih.gov/26163868
Publikováno v:
ChemInform. 42
The two-step sequence allows the access to a broad spectrum of multisubstituted benzofuran skeletons.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55d3337ab2ffd44d690579e076666cf6
https://doi.org/10.1002/chin.201150082
https://doi.org/10.1002/chin.201150082