Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Justin, Airas"'
Publikováno v:
ACS Central Science, Vol 9, Iss 12, Pp 2286-2297 (2023)
Externí odkaz:
https://doaj.org/article/363838db13104221970d71eb48afa70c
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
The COVID-19 pandemic was declared due to the spread of the novel coronavirus, SARS-CoV-2. Viral infection is caused by the interaction between the SARS-CoV-2 receptor binding domain (RBD) and the human ACE2 receptor (hACE2). Previous computational s
Externí odkaz:
https://doaj.org/article/7df89489dd91466b8fdbd9d69c2ec482
Autor:
Justin Airas, Catherine A. Bayas, Abdellah N'Ait Ousidi, Moulay Youssef Ait Itto, Aziz Auhmani, Mohamed Loubidi, M'hamed Esseffar, Julie A. Pollock, Carol A. Parish
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 4, Iss , Pp 100034- (2022)
COVID-19 is a global pandemic caused by infection with the SARS-CoV-2 virus. Remdesivir, a SARS-CoV-2 RNA polymerase inhibitor, is the only drug to have received widespread approval for treatment of COVID-19. The SARS-CoV-2 main protease enzyme (MPro
Externí odkaz:
https://doaj.org/article/db4160a9b6a04421a547b1d785c1f6e1
SARS-CoV-2 is a coronavirus that has created a global pandemic. The virus contains a spike protein which has been shown to bind to the ACE2 receptor on the surface of human cells. Vaccines have been developed that recognize elements of the SARS-CoV-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3172483c2debe55aebf8968623c46c6
https://doi.org/10.26434/chemrxiv-2022-30zcn
https://doi.org/10.26434/chemrxiv-2022-30zcn
Publikováno v:
Journal of Molecular Graphics and Modelling. 118:108360
SARS-CoV-2 is a coronavirus that has created a global pandemic. The virus contains a spike protein which has been shown to bind to the ACE2 receptor on the surface of human cells. Vaccines have been developed that recognize elements of the SARS-CoV-2
Autor:
Justin Airas, Catherine A. Bayas, Abdellah N'Ait Ousidi, Moulay Youssef Ait Itto, Aziz Auhmani, Mohamed Loubidi, M'hamed Esseffar, Julie A. Pollock, Carol A. Parish
COVID-19 is a global pandemic caused by infection with the SARS-CoV-2 virus. Remdesivir, a SARS-CoV-2 RNA polymerase inhibitor, is the only drug to have received widespread approval for treatment of COVID-19. The SARS-CoV-2 main protease enzyme (MPro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca26df16558373ce50fe7f05d19832b
https://doi.org/10.33774/chemrxiv-2021-zcmmb-v2
https://doi.org/10.33774/chemrxiv-2021-zcmmb-v2
Autor:
Carol A. Parish, Lauren M. McRae, Bill R. Miller, Justin Airas, Neda Ojaghlou, Cooper A. Taylor
Publikováno v:
Journal of chemical information and modeling. 61(1)
Recent experiments indicate that the C-Jun amino-terminal kinase-interacting protein 1 (JIP1) binds to and activates the c-Jun N-terminal kinase (JNK) protein. JNK is an integral part of cell apoptosis, and misregulation of this process is a causativ
Autor:
Cassidy N. Hilton, Alexis Blake, Kristen J. Rubenstein, Justin Airas, Carol A. Parish, Julie A. Pollock, Courtney L. Labrecque
Publikováno v:
ChemMedChem. 16(7)
Phosphorylation-dependent protein-protein interactions play a significant role in biological signaling pathways; therefore, small molecules that are capable of influencing these interactions can be valuable research tools and have potential as pharma
Autor:
Alexis Blake, Justin Airas, Carol A. Parish, Kristen J. Rubenstein, Cassidy N. Hilton, Julie A. Pollock, Courtney L. Labrecque
Publikováno v:
Journal of the Endocrine Society
MEMO1 (mediator of ErbB2-driven cell motility) is upregulated in breast tumors and has been correlated with poor prognosis in patients. As a scaffolding protein that binds to phosphorylated-tyrosine residues on receptors such as estrogen receptor and
Autor:
Cooper A. Taylor, Hunter D. Evans, Julie A. Pollock, Kristen J. Rubenstein, Carol A. Parish, Quincy McKoy, Jessica Y. Kim, Justin Airas, Courtney L. Labrecque, Madeline L. Newkirk
Publikováno v:
Biochemistry. 57(34)
ErbB2 signaling pathways are linked to breast cancer formation, growth, and aggression; therefore, understanding the behavior of proteins associated with these pathways as well as regulatory factors that influence ErbB2 function is essential. MEMO1 i