Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Jussuf T. Kaifi"'
Autor:
Ming Yang, Xiaoqiang Qi, Nan Li, Jussuf T. Kaifi, Shiyou Chen, Andrew A. Wheeler, Eric T. Kimchi, Aaron C. Ericsson, R. Scott Rector, Kevin F. Staveley-O’Carroll, Guangfu Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The interplay between western diet and gut microbiota drives the development of non-alcoholic fatty liver disease and its progression to non-alcoholic steatohepatitis. However, the specific microbial and metabolic mediators contributing to n
Externí odkaz:
https://doaj.org/article/b4b77dd13ef64968b1d1ab140e504033
Autor:
Emily Jean Wilson, Nagabhishek Sirpu Natesh, Parsa Ghadermazi, Ramesh Pothuraju, Dipakkumar R. Prajapati, Sanjit Pandey, Jussuf T. Kaifi, John R. Dodam, Jeffrey N. Bryan, Christian L. Lorson, Aude A. Watrelot, Jason M. Foster, Thomas J. Mansell, Siu Hung Joshua Chan, Surinder K. Batra, Jeyamkondan Subbiah, Satyanarayana Rachagani
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 539 (2023)
Gut microbiota plays a crucial role in inflammatory bowel diseases (IBD) and can potentially prevent IBD through microbial-derived metabolites, making it a promising therapeutic avenue. Recent evidence suggests that despite an unclear underlying mech
Externí odkaz:
https://doaj.org/article/bfe99edc3e3f4e3ba841de77417a9219
Autor:
Kanve N. Suvilesh, Yulia I. Nussbaum, Vijay Radhakrishnan, Yariswamy Manjunath, Diego M. Avella, Kevin F. Staveley-O’Carroll, Eric T. Kimchi, Aadel A. Chaudhuri, Chi-Ren Shyu, Guangfu Li, Klaus Pantel, Wesley C. Warren, Jonathan B. Mitchem, Jussuf T. Kaifi
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-8 (2022)
Abstract Background Circulating tumor cells (CTCs) are liquid biopsies that represent micrometastatic disease and may offer unique insights into future recurrences in non-small cell lung cancer (NSCLC). Due to CTC rarity and limited stability, no sta
Externí odkaz:
https://doaj.org/article/a2df1dda5fd74b0dbf8798da022a3a42
Autor:
Mouadh Barbirou, Amanda Miller, Yariswamy Manjunath, Arturo B. Ramirez, Nolan G. Ericson, Kevin F. Staveley-O’Carroll, Jonathan B. Mitchem, Wesley C. Warren, Aadel A. Chaudhuri, Yi Huang, Guangfu Li, Peter J. Tonellato, Jussuf T. Kaifi
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 2, Pp 750-763 (2022)
Non-small-cell lung cancer (NSCLC) accounts for most cancer-related deaths worldwide. Liquid biopsy by a blood draw to detect circulating tumor cells (CTCs) is a tool for molecular profiling of cancer using single-cell and next-generation sequencing
Externí odkaz:
https://doaj.org/article/330aa8b920e541a482532e69ead1d49b
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Microfluidics have been applied to filtration of rare tumor cells from the blood as liquid biopsies. Processing is highly limited by low flow rates and device clogging due to a single function of fluidic paths. A novel method using multifunc
Externí odkaz:
https://doaj.org/article/17765ab8ef0a4ba5a09651028283e7a5
Autor:
Jing Zhou, Yuexu Jiang, Yue Huang, Qiongling Wang, Jussuf T. Kaifi, Eric T. Kimchi, Chiswili Yves Chabu, Zhenguo Liu, Trupti Joshi, Guangfu Li
Publikováno v:
Translational Oncology, Vol 15, Iss 1, Pp 101262- (2022)
Pancreatic cancer (PaC) is resistant to immune checkpoint therapy, but the underlying mechanisms are largely unknown. In this study, we have established four orthotopic PaC murine models with different PaC cell lines by intra-pancreatic inoculation.
Externí odkaz:
https://doaj.org/article/a21934920a644ea9857ba22b86db5b6e
Autor:
Xinjian Liu, Hao Yuan, Jing Zhou, Qiongling Wang, Xiaoqiang Qi, Catharine Bernal, Diego Avella, Jussuf T. Kaifi, Eric T. Kimchi, Parrett Timothy, Kun Cheng, Yi Miao, Kuirong Jiang, Guangfu Li
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Pancreatic cancer (PC) is one of the most lethal human malignancies without effective treatment. In an effort to discover key genes and molecular pathways underlying PC growth, we have identified LIM domain only 7 (LMO7) as an under-investigated mole
Externí odkaz:
https://doaj.org/article/17e7022924fb4f8badc772f7ebad5284
Autor:
Yulia I. Nussbaum, Yariswamy Manjunath, Kanve N. Suvilesh, Wesley C. Warren, Chi-Ren Shyu, Jussuf T. Kaifi, Matthew A. Ciorba, Jonathan B. Mitchem
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4802 (2021)
Colorectal cancer (CRC) remains one of the deadliest malignancies worldwide despite recent progress in treatment strategies. Though immune checkpoint inhibition has proven effective for a number of other tumors, it offers benefits in only a small gro
Externí odkaz:
https://doaj.org/article/43fde5b4681a4ed4b2228d3e28452d5b
Autor:
Yariswamy Manjunath, David Porciani, Jonathan B. Mitchem, Kanve N. Suvilesh, Diego M. Avella, Eric T. Kimchi, Kevin F. Staveley-O’Carroll, Donald H. Burke, Guangfu Li, Jussuf T. Kaifi
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1872 (2020)
Although molecular mechanisms driving tumor progression have been extensively studied, the biological nature of the various populations of circulating tumor cells (CTCs) within the blood is still not well understood. Tumor cell fusion with immune cel
Externí odkaz:
https://doaj.org/article/282467b8956242e0b26281b16cf9148d
Autor:
Dai Liu, Guangfu Li, Diego M. Avella, Eric T. Kimchi, Jussuf T. Kaifi, Mark P. Rubinstein, E. Ramsay Camp, Don C. Rockey, Todd D. Schell, Kevin F. Staveley-O'Carroll
Publikováno v:
OncoImmunology, Vol 7, Iss 1 (2018)
Successful development of immunotherapeutic strategies for hepatocellular cancer (HCC) has been impeded by limited understanding of tumor-induced profound tolerance and lack of a clinically faithful HCC model. Recently, we developed a novel model tha
Externí odkaz:
https://doaj.org/article/0516ffea6c534568ae9148e8f9655751