Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jussi Naukkarinen"'
Autor:
Marius R. Robciuc, Jussi Naukkarinen, Alfredo Ortega-Alonso, Henna Tyynismaa, Taneli Raivio, Aila Rissanen, Jaakko Kaprio, Christian Ehnholm, Matti Jauhiainen, Kirsi H. Pietiläinen
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 8, Pp 1575-1582 (2011)
Animal studies have suggested that angiopoietin-like 4 (Angptl4) regulates adiposity through central and peripheral mechanisms. The aim of this study was to investigate whether serum concentration and adipose tissue expression of Angptl4 are associat
Externí odkaz:
https://doaj.org/article/5a0474069e9a4871b51c3961040d73ad
Autor:
Shuhei Nakanishi, Riikka Vikstedt, Sanni Söderlund, Miriam Lee-Rueckert, Anne Hiukka, Christian Ehnholm, Mikko Muilu, Jari Metso, Jussi Naukkarinen, Leena Palotie, Petri T. Kovanen, Matti Jauhiainen, Marja-Riitta Taskinen
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 2, Pp 183-192 (2009)
The main antiatherogenic function of HDL is to promote the efflux of cholesterol from peripheral cells and transport it to the liver for excretion in a process termed reverse cholesterol transport. The aim of this study was to evaluate the cholestero
Externí odkaz:
https://doaj.org/article/70430b0ac3304cfbaaca2c33689b2de1
Autor:
Aino Soro-Paavonen, Jussi Naukkarinen, Miriam Lee-Rueckert, Hiroshi Watanabe, Elina Rantala, Sanni Soderlund, Anne Hiukka, Petri T. Kovanen, Matti Jauhiainen, Leena Peltonen, Marja-Riitta Taskinen
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 6, Pp 1409-1416 (2007)
HDL promotes cholesterol efflux from peripheral cells via ABCA1 in the first step of reverse cholesterol transport (RCT). We investigated whether the early steps of RCT were disturbed in subjects with familial low HDL and an increased risk for early
Externí odkaz:
https://doaj.org/article/8e556901959c4d5a82a41828f5dbad3c
Autor:
Kirsi H Pietiläinen, Tomasz Róg, Tuulikki Seppänen-Laakso, Sam Virtue, Peddinti Gopalacharyulu, Jing Tang, Sergio Rodriguez-Cuenca, Arkadiusz Maciejewski, Jussi Naukkarinen, Anna-Liisa Ruskeepää, Perttu S Niemelä, Laxman Yetukuri, Chong Yew Tan, Vidya Velagapudi, Sandra Castillo, Heli Nygren, Tuulia Hyötyläinen, Aila Rissanen, Jaakko Kaprio, Hannele Yki-Järvinen, Ilpo Vattulainen, Antonio Vidal-Puig, Matej Orešič
Publikováno v:
PLoS Biology, Vol 9, Iss 6, p e1000623 (2011)
Identification of early mechanisms that may lead from obesity towards complications such as metabolic syndrome is of great interest. Here we performed lipidomic analyses of adipose tissue in twin pairs discordant for obesity but still metabolically c
Externí odkaz:
https://doaj.org/article/fcf716f0b0514305ae1327d2d91cb67b
Autor:
Jussi Naukkarinen, Ida Surakka, Kirsi H Pietiläinen, Aila Rissanen, Veikko Salomaa, Samuli Ripatti, Hannele Yki-Järvinen, Cornelia M van Duijn, H-Erich Wichmann, Jaakko Kaprio, Marja-Riitta Taskinen, Leena Peltonen, ENGAGE Consortium
Publikováno v:
PLoS Genetics, Vol 6, Iss 6, p e1000976 (2010)
To get beyond the "low-hanging fruits" so far identified by genome-wide association (GWA) studies, new methods must be developed in order to discover the numerous remaining genes that estimates of heritability indicate should be contributing to compl
Externí odkaz:
https://doaj.org/article/c2f8cc33a7ba400b8f4ea5c5142f2e00
Autor:
Kirsi H Pietiläinen, Jussi Naukkarinen, Aila Rissanen, Juha Saharinen, Pekka Ellonen, Heli Keränen, Anu Suomalainen, Alexandra Götz, Tapani Suortti, Hannele Yki-Järvinen, Matej Oresic, Jaakko Kaprio, Leena Peltonen
Publikováno v:
PLoS Medicine, Vol 5, Iss 3, p e51 (2008)
BackgroundThe acquired component of complex traits is difficult to dissect in humans. Obesity represents such a trait, in which the metabolic and molecular consequences emerge from complex interactions of genes and environment. With the substantial m
Externí odkaz:
https://doaj.org/article/9c1d27490def4fc7ae999f3a5beb2ce1
Autor:
Sinikka Torkkola, Jussi Naukkarinen
Publikováno v:
Media & Viestintä, Vol 26, Iss 4-5 (2003)
Externí odkaz:
https://doaj.org/article/1ea5a2748b9840c4a356bb50b600ba9e
Autor:
Nina Lundbom, Sini Heinonen, Jussi Naukkarinen, Ursula Turpeinen, Tomi S. Mikkola, Kirsi H. Pietiläinen, Antti Hakkarainen, Jesper Lundbom, Aila Rissanen, Veera Vihma, Esa Hämäläinen, Matti J. Tikkanen, Jaakko Kaprio
Publikováno v:
Steroids. 140:24-31
Objective: Obesity may alter serum steroid concentrations and metabolism. We investigated this in healthy young women with increased body fat and their leaner co-twin sisters. Design: Age and genetic background both strongly influence serum steroid l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7bbce87150908da80f97f3e2b80db4
https://doi.org/10.1016/j.steroids.2018.08.006
https://doi.org/10.1016/j.steroids.2018.08.006
Autor:
Sini Heinonen, Jesper Lundbom, Kirsi H. Pietiläinen, Antti Hakkarainen, Ursula Turpeinen, Jaakko Kaprio, Tomi S. Mikkola, Veera Vihma, Nina Lundbom, Esa Hämäläinen, Jussi Naukkarinen, Aila Rissanen, Matti J. Tikkanen
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 172:98-105
Obesity and ageing are associated with lower serum testosterone levels in men. How fat distribution or adipose tissue metabolism, independent of genetic factors and age, are related to sex steroid metabolism is less clear. We studied the associations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8434aa1b16acb5742e398816866ca00
https://doi.org/10.1016/j.jsbmb.2017.06.007
https://doi.org/10.1016/j.jsbmb.2017.06.007
Autor:
Sini Heinonen, Anu Suomalainen, Kirsi H. Pietiläinen, Antti Hakkarainen, Amaia Rodríguez, Jaakko Kaprio, J. Lundbom, Lilli Saarinen, Nina Lundbom, Eeva Moilanen, Peter Arner, Jussi Naukkarinen, Sampsa Hautaniemi, Aila Rissanen, Gema Frühbeck, Katriina Vuolteenaho
Publikováno v:
International Journal of Obesity. 38:1423-1431
Adipocyte size and number have been suggested to predict the development of metabolic complications in obesity. However, the genetic and environmental determinants behind this phenomenon remain unclear.We studied this question in rare-weight discorda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1259eeae6b6488958dbf8e7b1959eb8
https://doi.org/10.1038/ijo.2014.31
https://doi.org/10.1038/ijo.2014.31