Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Jussara M do Carmo"'
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0184805 (2017)
The hypothalamic-pituitary-adrenal (HPA) axis has been postulated to play a major role in mediating the antidiabetic effects of leptin. We tested if the pituitary is essential for the chronic central nervous system mediated actions of leptin on metab
Externí odkaz:
https://doaj.org/article/01c67710580341bd976e05e554216ea5
Autor:
Samar Rezq, Alexandra M. Huffman, Jelina Basnet, Amira E. Alsemeh, Jussara M. do Carmo, Licy L. Yanes Cardozo, Damian G. Romero
Publikováno v:
Biology of Sex Differences, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background Polycystic ovary syndrome (PCOS), the most common endocrine disorder in premenopausal women, is associated with increased obesity, hyperandrogenism, and altered brown adipose tissue (BAT) thermogenesis. MicroRNAs play critical fun
Externí odkaz:
https://doaj.org/article/6e0e7d9613c14579bd4d70779b42e924
Autor:
Xuan Li, Zhen Wang, Alan J. Mouton, Ana C. M. Omoto, Alexandre A. da Silva, Jussara M. do Carmo, Ji Li, John E. Hall
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 21 (2024)
Background Sesn2 (Sestrin2) is a stress‐induced protein that provides protective effects during myocardial ischemia and reperfusion (I/R) injury, while endoplasmic reticulum (ER) stress may be a pivotal mediator of I/R injury. The goal of this stud
Externí odkaz:
https://doaj.org/article/cc6fb2343f3d44e6802986a84ec00bec
Autor:
Marina T Durand, Christiane Becari, Mauro de Oliveira, Jussara M do Carmo, Carlos Alberto Aguiar Silva, Cibele M Prado, Rubens Fazan, Helio C Salgado
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104476 (2014)
The effect of pyridostigmine (PYR)--an acetylcholinesterase inhibitor--on hemodynamics and cardiac autonomic control, was never studied in conscious myocardial infarcted mice. Telemetry transmitters were implanted into the carotid artery under isoflu
Externí odkaz:
https://doaj.org/article/27ffadec8be34591ab6032d351c71ecf
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2024)
Recent evidence from our lab and others suggests that metabolic reprogramming of immune cells drives changes in immune cell phenotypes along the inflammatory-to-reparative spectrum and plays a critical role in mediating the inflammatory responses to
Externí odkaz:
https://doaj.org/article/05f813b272194508ba4cbf68393801b8
Autor:
Alan J. Mouton, Nikaela M. Aitken, Sydney P. Moak, Jussara M. do Carmo, Alexandre A. da Silva, Ana C. M. Omoto, Xuan Li, Zhen Wang, Alexandra C. Schrimpe-Rutledge, Simona G. Codreanu, Stacy D. Sherrod, John A. McLean, John E. Hall
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionMetabolic reprogramming from glycolysis to the mitochondrial tricarboxylic acid (TCA) cycle and oxidative phosphorylation may mediate macrophage polarization from the pro-inflammatory M1 to the anti-inflammatory M2 phenotype. We hypothesi
Externí odkaz:
https://doaj.org/article/5ddb9397e379446ebc06b0ae59b7d981
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Macrophages play critical roles in mediating and resolving tissue injury as well as tissue remodeling during cardiorenal disease. Altered immunometabolism, particularly macrophage metabolism, is a critical underlying mechanism of immune dysfunction a
Externí odkaz:
https://doaj.org/article/ca52ae620eca47f180159bee7db05ddc
Autor:
Ana C. M. Omoto, Jussara M. do Carmo, Benjamin Nelson, Nikaela Aitken, Xuemei Dai, Sydney Moak, Elizabeth Flynn, Zhen Wang, Alan J. Mouton, Xuan Li, John E. Hall, Alexandre A. da Silva
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 21 (2022)
Background Therapeutic strategies for preventing paradoxical reperfusion injury after myocardial ischemia are limited. We tested whether central nervous system actions of leptin induce important protective effects on cardiac function and metabolism a
Externí odkaz:
https://doaj.org/article/38d6df726bf24332a2f6cb009244e4ba
Autor:
Xuan Li, Qingguo Lu, Yunguang Qiu, Jussara M. do Carmo, Zhen Wang, Alexandre A. da Silva, Alan Mouton, Ana C. M. Omoto, Michael E. Hall, Ji Li, John E. Hall
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 6 (2021)
Background We determined if the sodium glucose co‐transporter 2 inhibitor empagliflozin attenuates pressure overload‐induced heart failure in non‐diabetic mellitus mice by direct cardiac effects and the mechanisms involved. Methods and Results
Externí odkaz:
https://doaj.org/article/06d54fe46ce34956bd6c16e9fee86fdf
Autor:
Alan J. Mouton, Elizabeth R. Flynn, Sydney P. Moak, Xuan Li, Alexandre A. da Silva, Zhen Wang, Jussara M. do Carmo, Michael E. Hall, John E. Hall
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 6 (2021)
Background Obesity and hypertension are risk factors for myocardial infarction (MI); however, their potential interactions on post‐MI outcomes are unclear. We examined interactions of obesity and hypertensionon post‐MI function, remodeling, metab
Externí odkaz:
https://doaj.org/article/b0416d4529144ea59f84e79fec8ba225