Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Jussara, Amato"'
Autor:
Atefeh Moshari-Nasirkandi, Nunzia Iaccarino, Francesca Romano, Giulia Graziani, Abolfazl Alirezalu, Hadi Alipour, Jussara Amato
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract In recent years, the exploration of the therapeutic potential of Salvia has gained considerable attention, leading to a growing number of scientific studies emphasizing its pharmacological properties. Despite this, therapeutic applications o
Externí odkaz:
https://doaj.org/article/85cf876ee8fb4f2090422db25401ac20
Autor:
Alessio Nocentini, Anna Di Porzio, Alessandro Bonardi, Carla Bazzicalupi, Andrea Petreni, Tarita Biver, Silvia Bua, Simona Marzano, Jussara Amato, Bruno Pagano, Nunzia Iaccarino, Stefano De Tito, Stefano Amente, Claudiu T. Supuran, Antonio Randazzo, Paola Gratteri
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
A novel class of compounds designed to hit two anti-tumour targets, G-quadruplex structures and human carbonic anhydrases (hCAs) IX and XII is proposed. The induction/stabilisation of G-quadruplex structures by small molecules has emerged as an antic
Externí odkaz:
https://doaj.org/article/72c74b1aaac342a2836205f0ff910408
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The Lamiaceae family encompasses numerous species highly valued for their applications in medicine, food, and cosmetics. In order to screen the Lamiaceae family and discover new sources of phytochemicals and antioxidants, we comprehensively
Externí odkaz:
https://doaj.org/article/be625d89fd0d4dc99c6bf7fecfbbd4e9
Autor:
Elisa De Piante, Federica D’Aria, Luisa M. R. Napolitano, Jussara Amato, Simone Pirrello, Silvia Onesti, Concetta Giancola
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Despite numerous reports on the interactions of G-quadruplexes (G4s) with helicases, systematic analysis addressing the selectivity and specificity of each helicase towards a variety of G4 topologies are scarce. Among the helicases able to u
Externí odkaz:
https://doaj.org/article/bf1b7cfb418447afa685ce50eff0faba
Autor:
Andrea P. Falanga, Antonio Lupia, Lorella Tripodi, Carmine M. Morgillo, Federica Moraca, Giovanni N. Roviello, Bruno Catalanotti, Jussara Amato, Lucio Pastore, Vincenzo Cerullo, Stefano D'Errico, Gennaro Piccialli, Giorgia Oliviero, Nicola Borbone
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e24599- (2024)
Peptide Nucleic Acids (PNAs) represent a promising tool for gene modulation in anticancer treatment. The uncharged peptidyl backbone and the resistance to chemical and enzymatic degradation make PNAs highly advantageous to form stable hybrid complexe
Externí odkaz:
https://doaj.org/article/d1d54d77b71247aba8e291dd32760c27
Autor:
Maria Rosaria Ambrosio, Teresa Migliaccio, Fabiana Napolitano, Sarah Di Somma, Giovanni Maneli, Jussara Amato, Bruno Pagano, Antonio Randazzo, Giuseppe Portella, Pietro Formisano, Anna Maria Malfitano
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Background G-quadruplex (G4) motifs are nucleic acid secondary structures observed in mammalian genomes and transcriptomes able to regulate various cellular processes. Several small molecules have been developed so far to modulate G4 stabili
Externí odkaz:
https://doaj.org/article/61e379bd56254b75b0a1446cbd630233
Autor:
Greta Donati, Vincenzo Maria D’Amore, Pasquale Russomanno, Linda Cerofolini, Jussara Amato, Simona Marzano, Maria Salobehaj, Domenico Rizzo, Giulia Assoni, Alfonso Carotenuto, Valeria La Pietra, Daniela Arosio, Pierfausto Seneci, Marco Fragai, Diego Brancaccio, Francesco Saverio Di Leva, Luciana Marinelli
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3355-3368 (2023)
Today it is widely recognized that the PD-1/PD-L1 axis plays a fundamental role in escaping the immune system in cancers, so that anti-PD-1/PD-L1 antibodies have been evaluated for their antitumor properties in more than 1000 clinical trials. As a re
Externí odkaz:
https://doaj.org/article/3bd14ba4f0aa401ca2a63ca4a266835e
Autor:
Nunzia Iaccarino, Jussara Amato, Bruno Pagano, Anna Di Porzio, Matteo Micucci, Luca Bolelli, Rita Aldini, Ettore Novellino, Roberta Budriesi, Antonio Randazzo
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1041-1050 (2019)
Phytosterols are known to reduce plasma cholesterol levels and thereby reduce cardiovascular risk. Studies conducted on human and animal models have demonstrated that these compounds have also anti-inflammatory effects. Recently, an experimental coli
Externí odkaz:
https://doaj.org/article/870da9523ca84240ab09f461e85b29b8
Autor:
Fabiana Napolitano, Sarah Di Somma, Giuliano Castellano, Jussara Amato, Bruno Pagano, Antonio Randazzo, Giuseppe Portella, Anna Maria Malfitano
Publikováno v:
Cells, Vol 11, Iss 16, p 2482 (2022)
G-quadruplexes (G4s) are nucleic secondary structures characterized by G-tetrads. G4 motif stabilization induces DNA damage and cancer cell death; therefore, G4-targeting small molecules are the focus of clinical investigation. DNA destabilization in
Externí odkaz:
https://doaj.org/article/4ceed773775b43fb963286e084cfc764
Autor:
Francesco D'Amico, Raffaele Graziano, Federica D'Aria, Pasquale Russomanno, Silvia Di Fonzo, Jussara Amato, Bruno Pagano
Publikováno v:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 300:122901
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f8b88939f97e3c7cc2d557e43df7b35
https://doi.org/10.1016/j.saa.2023.122901
https://doi.org/10.1016/j.saa.2023.122901