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Publikováno v:
Tetrahedron. 66:3995-4001
Reduction of keto esters is a valuable alternative to produce diols. Sodium borohydride/MeOH system at room temperature and short reaction time efficiently reduced α, β, γ, and δ-keto esters having α-keto esters as the most reactive. The ester f
Publikováno v:
ChemInform. 41
The reduction of α-, β-, and γ-keto esters to the corresponding diols using NaBH4/MeOH is shown to be accelerated by the formation of five- or six-membered alkoxyborane-derived ring intermediates.