Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jury Gladkich"'
Autor:
Li Liu, Shanshan Han, Xi Xiao, Xuefeng An, Jury Gladkich, Ulf Hinz, Stefan Hillmer, Torsten Hoppe-Tichy, Yi Xu, Michael Schaefer, Oliver Strobel, Ingrid Herr
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-15 (2022)
Abstract Glucocorticoids (GCs) are widely used in tumor therapy to reduce tumor growth, inflammation, edema, and other side effects. Controversially, GCs may also cause the progression of highly aggressive pancreatic ductal adenocarcinoma (PDAC). Bec
Externí odkaz:
https://doaj.org/article/f01c7932198e4284b96652265c82231c
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pancreatic ductal adenocarcinoma (PDAC) is among the leading causes of cancer mortality, and new therapeutic options are urgently needed. Long noncoding RNA H19 (H19) is known to promote PDAC progression, but the downstream genes of H19 are largely u
Externí odkaz:
https://doaj.org/article/a8170edc0fbd49198c35866b5b9cc2e4
Autor:
Huihui Ji, Zhimin Qi, Daniel Schrapel, Monika Le, Yiqiao Luo, Bin Yan, Jury Gladkich, Michael Schaefer, Li Liu, Ingrid Herr
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Broccoli-derived isothiocyanate sulforaphane inhibits inflammation and cancer. Sulforaphane may support healthy aging, but the underlying detailed mechanisms are unclear. We used the C. elegans nematode model to address this question. Wild-type and 4
Externí odkaz:
https://doaj.org/article/3afcecfa695644f9942df44b98c6a16c
Autor:
Libo Yin, Xi Xiao, Christina Georgikou, Yiqiao Luo, Li Liu, Jury Gladkich, Wolfgang Gross, Ingrid Herr
Publikováno v:
Molecular Therapy: Oncolytics, Vol 14, Iss , Pp 74-81 (2019)
Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal tumors, with poor therapeutic options in the advanced state. The broccoli-derived anti-inflammatory agent sulforaphane was shown to inhibit the progression of pancreatic cancer and othe
Externí odkaz:
https://doaj.org/article/8209295971af4b3e9edee29d229f63bd
Autor:
Alexei V Salnikov, Li Liu, Mitja Platen, Jury Gladkich, Olga Salnikova, Eduard Ryschich, Jürgen Mattern, Gerhard Moldenhauer, Jens Werner, Peter Schemmer, Markus W Büchler, Ingrid Herr
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46391 (2012)
Tumor hypoxia induces epithelial-mesenchymal transition (EMT), which induces invasion and metastasis, and is linked to cancer stem cells (CSCs). Whether EMT generates CSCs de novo, enhances migration of existing CSCs or both is unclear. We examined p
Externí odkaz:
https://doaj.org/article/df3bdecc117e4199947f2616eceb447d
Autor:
Bin Yan, Li Liu, Lian Zhao, Ulf Hinz, Yiqiao Luo, Xuefeng An, Jury Gladkich, Carolina de la Torre, Zhenhua Huang, Daniel Schrapel, Wolfgang Gross, Franco Fortunato, Michael Schaefer, Matthias M Gaida, Ingrid Herr
Publikováno v:
Matrix Biology. 114:84-107
Several collagen subtypes are involved in pancreatic ductal adenocarcinoma (PDAC) desmoplasia, which constrains therapeutic efficacy. We evaluated collagen type VIII alpha 1 chain (COL8A1), whose function in PDAC is currently unknown. We identified C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d958f92ed07f0c51503ba8222c8e222
https://doi.org/10.1016/j.matbio.2022.11.002
https://doi.org/10.1016/j.matbio.2022.11.002
Autor:
Ingrid Herr, Gerhard Moldenhauer, Markus W. Büchler, Frank Momburg, Thomas Giese, Nathalia Giese, Eduard Ryschich, Olga Salnikova, Georgios Kallifatidis, Li Liu, Jury Gladkich, Sabine Ottinger, Alexei V. Salnikov, Ariane Groth
PDF file - 216K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06daf19939e981ae4583034dd937e141
https://doi.org/10.1158/1078-0432.22443867.v1
https://doi.org/10.1158/1078-0432.22443867.v1
Autor:
Ingrid Herr, Gerhard Moldenhauer, Markus W. Büchler, Frank Momburg, Thomas Giese, Nathalia Giese, Eduard Ryschich, Olga Salnikova, Georgios Kallifatidis, Li Liu, Jury Gladkich, Sabine Ottinger, Alexei V. Salnikov, Ariane Groth
PDF file - 49K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d948b079d05ce089302a3ceb6dfbcec
https://doi.org/10.1158/1078-0432.22443864.v1
https://doi.org/10.1158/1078-0432.22443864.v1
Autor:
Ingrid Herr, Gerhard Moldenhauer, Markus W. Büchler, Frank Momburg, Thomas Giese, Nathalia Giese, Eduard Ryschich, Olga Salnikova, Georgios Kallifatidis, Li Liu, Jury Gladkich, Sabine Ottinger, Alexei V. Salnikov, Ariane Groth
Purpose: To enhance T-cell responsiveness toward cancer cells, we overexpressed TRAIL in lymphocytes, as this death ligand induces tumor-specific apoptosis. To increase contact time of lymphocytes with tumor cells and thereby of TRAIL with its death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e2b539d7e9b77d4466b079c37736fd
https://doi.org/10.1158/1078-0432.c.6519987
https://doi.org/10.1158/1078-0432.c.6519987
Autor:
Ingrid Herr, Gerhard Moldenhauer, Markus W. Büchler, Frank Momburg, Thomas Giese, Nathalia Giese, Eduard Ryschich, Olga Salnikova, Georgios Kallifatidis, Li Liu, Jury Gladkich, Sabine Ottinger, Alexei V. Salnikov, Ariane Groth
PDF file - 104K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2017f8388db1f6d94a58f7639cb704
https://doi.org/10.1158/1078-0432.22443861
https://doi.org/10.1158/1078-0432.22443861