Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jurrian K. de Kanter"'
Autor:
Eline J. M. Bertrums, Jurrian K. de Kanter, Lucca L. M. Derks, Mark Verheul, Laurianne Trabut, Markus J. van Roosmalen, Henrik Hasle, Evangelia Antoniou, Dirk Reinhardt, Michael N. Dworzak, Nora Mühlegger, Marry M. van den Heuvel-Eibrink, C. Michel Zwaan, Bianca F. Goemans, Ruben van Boxtel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Therapy-related myeloid neoplasms (t-MN) arise as a complication of chemo- and/or radiotherapy. Although t-MN can occur both in adult and childhood cancer survivors, the mechanisms driving therapy-related leukemogenesis likely vary across di
Externí odkaz:
https://doaj.org/article/133d1d021aba4ed18ed60a7266e30b7f
Autor:
Anne Margriet Heijink, Colin Stok, David Porubsky, Eleni Maria Manolika, Jurrian K. de Kanter, Yannick P. Kok, Marieke Everts, H. Rudolf de Boer, Anastasia Audrey, Femke J. Bakker, Elles Wierenga, Marcel Tijsterman, Victor Guryev, Diana C. J. Spierings, Puck Knipscheer, Ruben van Boxtel, Arnab Ray Chaudhuri, Peter M. Lansdorp, Marcel A. T. M. van Vugt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Sister chromatid exchanges (SCEs) are considered to be products of homologous recombination repair. The authors show that SCEs can arise independently of homologous recombination due to processing of replication intermediates during mitosis.
Externí odkaz:
https://doaj.org/article/6a7ed7595d2b4f12a042a1aaa930abc6
Autor:
Axel Rosendahl Huber, Anaïs J.C. N. van Leeuwen, Flavia Peci, Jurrian K. de Kanter, Eline J.M. Bertrums, Ruben van Boxtel
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101361- (2022)
Summary: Mutational signatures have been identified in cancer genomes, providing information about the causes of cancer and treatment vulnerabilities. This protocol describes an assay to determine the genotoxic mechanisms underlying these signatures
Externí odkaz:
https://doaj.org/article/d05aa286286b467aa5b08f7de37027c0
Autor:
Ruben van Boxtel, Bianca F. Goemans, C. Michel Zwaan, Hester A. de Groot-Kruseman, Markus J. van Roosmalen, Rurika Oka, Marry M. van den Heuvel-Eibrink, Mark Verheul, Anaïs J.C.N. van Leeuwen, Arianne M. Brandsma, Jurrian K. de Kanter, Axel K.M. Rosendahl Huber, Eline J.M. Bertrums
Childhood cancer survivors are confronted with various chronic health conditions like therapy-related malignancies. However, it is unclear how exposure to chemotherapy contributes to the mutation burden and clonal composition of healthy tissues early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f08e9ef66548e287e4204011bb36a9a
https://doi.org/10.1158/2159-8290.c.6549550
https://doi.org/10.1158/2159-8290.c.6549550
Autor:
Ruben van Boxtel, Bianca F. Goemans, C. Michel Zwaan, Hester A. de Groot-Kruseman, Markus J. van Roosmalen, Rurika Oka, Marry M. van den Heuvel-Eibrink, Mark Verheul, Anaïs J.C.N. van Leeuwen, Arianne M. Brandsma, Jurrian K. de Kanter, Axel K.M. Rosendahl Huber, Eline J.M. Bertrums
Supplementary Figure from Elevated Mutational Age in Blood of Children Treated for Cancer Contributes to Therapy-Related Myeloid Neoplasms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f5187b9b26fb7ee257c2d7ae4cc5a5
https://doi.org/10.1158/2159-8290.22541080
https://doi.org/10.1158/2159-8290.22541080
Autor:
Jurrian K. de Kanter, Thanasis Margaritis, Auke Beishuizen, Marijn Scheijde-Vermeulen, Liset Westera, Arianne M. Brandsma, Ruben van Boxtel, Friederike Meyer-Wentrup
Publikováno v:
Blood Cancer Discovery. 3:A37-A37
Cure rates of classical Hodgkin Lymphoma (cHL) in children and young adult patients currently exceed 90%. Nonetheless, survivors are confronted with chronic therapy-related health conditions such as infertility, cardiovascular disease, and high rates
Autor:
Freek Manders, Mirjam E. Belderbos, Jurrian K. de Kanter, Markus J van Roosmalen, Marc Bierings, Rurika Oka, Ruben van Boxtel, Flavia Peci, Mark Verheul, Axel Rosendahl Huber, Arianne M. Brandsma, E.J.M. Bertrums, Anaïs van Leeuwen
Publikováno v:
Cell Stem Cell
Cell Stem Cell, 28(10), 1726-1739.e6. Cell Press
Cell Stem Cell, 28(10), 1726-1739.e6. Cell Press
Summary Genetic instability is a major concern for successful application of stem cells in regenerative medicine. However, the mutational consequences of the most applied stem cell therapy in humans, hematopoietic stem cell transplantation (HSCT), re
Autor:
Frank C. P. Holstege, Thanasis Margaritis, Jurrian K. de Kanter, Tito Candelli, Philip Lijnzaad
Publikováno v:
Nucleic Acids Research
Cell type identification is essential for single-cell RNA sequencing (scRNA-seq) studies, currently transforming the life sciences. CHETAH (CHaracterization of cEll Types Aided by Hierarchical classification) is an accurate cell type identification a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640c51b662345b8399f19bfe77ef2526
Autor:
Eline J.M. Bertrums, Axel K.M. Rosendahl Huber, Jurrian K. de Kanter, Arianne M. Brandsma, Anaïs J.C.N. van Leeuwen, Mark Verheul, Marry M. van den Heuvel-Eibrink, Rurika Oka, Markus J. van Roosmalen, Hester A. de Groot-Kruseman, C. Michel Zwaan, Bianca F. Goemans, Ruben van Boxtel
Publikováno v:
Cancer Discovery, 12(8), 1860-1872. American Association for Cancer Research Inc.
Cancer Discovery
Cancer Discovery
Childhood cancer survivors are confronted with various chronic health conditions like therapy-related malignancies. However, it is unclear how exposure to chemotherapy contributes to the mutation burden and clonal composition of healthy tissues early