Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jurjen Westra"'
Autor:
Matthew Salter, Emily Corfield, Aroul Ramadass, Francis Grand, Jayne Green, Jurjen Westra, Chun Ren Lim, Lucy Farrimond, Emily Feneberg, Jakub Scaber, Alexander Thompson, Lynn Ossher, Martin Turner, Kevin Talbot, Merit Cudkowicz, James Berry, Ewan Hunter, Alexandre Akoulitchev
Publikováno v:
EBioMedicine, Vol 33, Iss , Pp 169-184 (2018)
Background: The identification of blood-based biomarkers specific to the diagnosis of amyotrophic lateral sclerosis (ALS) is an active field of academic and clinical research. While inheritance studies have advanced the field, a majority of patients
Externí odkaz:
https://doaj.org/article/e899e2928af14780be7b580a89851079
Autor:
Ewan Hunter, Christina Koutsothanasi, Alexandre Akoulitchev, Jennifer Back, Ryan Powell, Jurjen Westra, Matthew Salter, Aroul Ramadass, Francis H. Grand, Jayne Green
Publikováno v:
Edelweiss: Psychiatry Open Access. :1-6
Background:Huntington’s disease (HD) is a progressive neurodegenerative condition that causes degeneration of neurons in the brain, ultimately leading to death. The root cause of HD is an expanded trinucleotide cytosine-adenine-guanine (CAG) repeat
Autor:
Adam Wilson, Paulina Brajer, Ryan Powell, Parnall Matthew, Alexandre Akoulitchev, Andrew Barlow, Katzinski Aemilia, Peter A. Robbins, William Messner, Amanda E Brunton, Christina Koutsothanasi, Dmitri Pchejetski, Lavin Thomas, Zoe L Lyski, Rama Vancheeswaran, Francisco Coroado Santos, Ann Dring, Jane Mellor, Matthew Salter, Aroul Ramadass, Jurjen Westra, Williams Catriona, Benedict Egan, Ewan Hunter
The COVID-19 pandemic has raised several global public health challenges to which the international medical community have responded. Diagnostic testing and the development of vaccines against the SARS-CoV-2 virus have made remarkable progress to dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c8a6ca4fc6ceb291d6629cc6d31bf9e
https://doi.org/10.1101/2021.06.21.21259145
https://doi.org/10.1101/2021.06.21.21259145
Autor:
Matthew Salter, Aroul Ramadass, Elliott C. R. Hall, Georgina K. Stebbings, Jurjen Westra, Chris Murgatroyd, Brian Cunniffe, Ewan Hunter, Alexandre Akoulitchev, Lee Harle, Alun G. Williams
Publikováno v:
Genes, Vol 11, Iss 905, p 905 (2020)
Genes
Genes
The integration of genetic and environmental factors that regulate the gene expression patterns associated with exercise adaptation is mediated by epigenetic mechanisms. The organisation of the human genome within three-dimensional space, known as ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f92552b2f999c662b71a49f1119811
https://e-space.mmu.ac.uk/626309/
https://e-space.mmu.ac.uk/626309/
Autor:
Alexandre Akoulitchev, Kirsten Mundt, Ewan Hunter, Aroul Ramadass, Jayne Green, Ronald McCord, Jurjen Westra
Publikováno v:
Translational Medicine Communications, Vol 5, Iss 1, Pp 1-13 (2020)
Background Diffuse large B-cell lymphoma (DLBCL) is a heterogenous blood cancer, but can be broadly classified into two main subtypes, germinal center B-cell-like (GCB) and activated B-cell-like (ABC). GCB and ABC subtypes have very different clinica
Autor:
Michael Benatar, Terry Heiman-Patterson, Merit Cudkowicz, Stephen Apple, Stanley H. Appel, James D. Berry, Jeremy M. Shefner, Jurjen Westra, Robert Bowser, Sally K. Nelson, Angela Genge, Clifton L. Gooch, Benjamin Rix Brooks, Wendy Agnese, Charlotte Merrill
Publikováno v:
Neurology: Clinical Practice
article-version (Version of Record) 3
article-version (Version of Record) 3
ObjectivesTo identify putative biomarkers that may serve as quantifiable, biological, nonclinical measures of the pharmacodynamic effect of edaravone in amyotrophic lateral sclerosis (ALS) and to report real-world treatment outcomes.MethodsThis is a
Autor:
Francis Grand, Emily Corfield, Alexandre Akoulitchev, Lynn Ossher, Ewan Hunter, Martin R Turner, Lucy Farrimond, Emily Feneberg, Chun Ren Lim, Merit Cudkowicz, Jayne Green, Jurjen Westra, Alexander G. Thompson, Matthew Salter, Aroul Ramadass, Jakub Scaber, Kevin Talbot, James D. Berry
Publikováno v:
EBioMedicine
Background The identification of blood-based biomarkers specific to the diagnosis of amyotrophic lateral sclerosis (ALS) is an active field of academic and clinical research. While inheritance studies have advanced the field, a majority of patients d
Autor:
Ryan Powell, Ewan Hunter, Jennifer Back, Jurjen Westra, Alexandre Akoulitchev, Christina Koutsothanasi, Francis H. Grand, Matthew Salter, Aroul Ramadass, Jayne Green
Publikováno v:
F1000Research. 7:1757
Background:Huntington’s disease (HD) is a progressive neurodegenerative condition that causes degeneration of neurons in the brain, ultimately leading to death. The root cause of HD is an expanded trinucleotide cytosine-adenine-guanine (CAG) repeat
Autor:
Jurjen Westra, Patrick Groeneveld
Publikováno v:
SLIP
Fast congestion prediction is essential for congestion reduction techniques at different stages of the flow. Probabilistic congestion estimation methods model congestion after placement by considering the probability a wire will be routed over differ
Publikováno v:
ISPD
Congestion is a fundamental problem in VLSI design flows. Typically, it is handled by feeding back density information to the placers and routers. Fast and accurate congestion estimation is key in order to obtain a design flow with less iterations an