Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jurjen Duintjer Tebbens"'
Autor:
Karel Hloch, Martin Doseděl, Jurjen Duintjer Tebbens, Lenka Žaloudková, Helena Medková, Jiří Vlček, Tomáš Soukup, Petr Pávek
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Cardiovascular diseases (CVDs) lead to higher morbidity and mortality in rheumatoid arthritis; thus, we aimed to determine whether patients who had discontinued methotrexate treatment before the study enrollment (group MTX 0) were at a higher risk of
Externí odkaz:
https://doaj.org/article/30389219139b4a449c415b8ceeac9d85
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1653 (2022)
Flowability is among the most important properties of powders, especially when fine particle size fractions need to be processed. In this study, our goal was to find a possibly simple but accurate mathematical model for predicting the mass flow rate
Externí odkaz:
https://doaj.org/article/f57a0727b72c4a2d8104b3a40c36b79b
This book aims to give an encyclopedic overview of the state-of-the-art of Krylov subspace iterative methods for solving nonsymmetric systems of algebraic linear equations and to study their mathematical properties. Solving systems of algebraic linea
Publikováno v:
PAMM. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3195c0b905c63ed4d3e5014b8ec130c6
https://doi.org/10.1002/pamm.202200268
https://doi.org/10.1002/pamm.202200268
Autor:
Petr Pavek, Štěpán Šembera, Karel Hloch, Jana Nekvindová, Tomáš Veleta, Ivan Barvík, Martin Doseděl, Jurjen Duintjer Tebbens, Tomáš Soukup
Publikováno v:
Pharmacogenomics. 21:735-749
Aim: We studied the influence of coffee consumption on the therapeutic effect of methotrexate (MTX) in patients with rheumatoid arthritis (RA) sorted according to ADORA2A genotypes. Patients & methods: 82 RA patients were dichotomized according to ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ff500ee5d9e4fe0819c43c0a7038f8
https://doi.org/10.2217/pgs-2020-0042
https://doi.org/10.2217/pgs-2020-0042
Publikováno v:
Numerical Algorithms. 84:1329-1352
The paper gives a characterization of all linear systems such that when restarted GMRES is applied, prescribed admissible residual norms and (harmonic) Ritz values for all iterations inside the individual cycles are generated. Additionally, the syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::056e8aae317b49ac1ee1ad76c5bc0145
https://doi.org/10.1007/s11075-019-00846-z
https://doi.org/10.1007/s11075-019-00846-z
Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids
Publikováno v:
Archives of toxicology. 96(1)
The pregnane X receptor (PXR) is a ligand-activated nuclear receptor controlling hepatocyte expression of numerous genes. Although expression changes in xenobiotic-metabolizing, lipogenic, gluconeogenic and bile acid synthetic genes have been describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05707940eb9426d36a983100617aaade
https://pubmed.ncbi.nlm.nih.gov/34689256
https://pubmed.ncbi.nlm.nih.gov/34689256
Is Computer-Assisted Aminoglycoside Dosing Managed by a Pharmacist a Safety Tool of Pharmacotherapy?
Autor:
M. Hojný, Jiri Vlcek, J. Rychlíčková, Petr Pavek, E. Dvořáčková, O. Suchopár, Jurjen Duintjer Tebbens, B. Kováčová
Publikováno v:
Physiological Research. :S87-S96
This pilot prospective study verified the hypothesis that use of computer-assisted therapeutic drug monitoring of aminoglycosides by pharmacists leads to better safety therapeutic outcomes and cost avoidance than only concentration measurement and do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2d58d1b969b3e3939d0b766032000b
https://doi.org/10.33549/physiolres.934329
https://doi.org/10.33549/physiolres.934329
Publikováno v:
Applications of Mathematics. 64:253-277
A pharmacodynamic model introduced earlier in the literature for in silico prediction of rifampicin-induced CYP3A4 enzyme production is described and some aspects of the involved curve-fitting based parameter estimation are discussed. Validation with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cb7f1c48d92ee0264a1b6a62b24a917
https://doi.org/10.21136/am.2019.0284-18
https://doi.org/10.21136/am.2019.0284-18
Autor:
Petra Svačinová, Julia Marushka, Jana Brokešová, Jurjen Duintjer Tebbens, Ondrej Holas, Barbora Vraníková, Zdenka Šklubalová
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 165
Albeit the preparation of liquisolid systems represents an innovative approach to enhance the dissolution of poorly soluble drugs, their broader utilization is still limited mainly due to the problematic conversion of the liquid into freely flowing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3351715b0750173851991b91af4774
https://pubmed.ncbi.nlm.nih.gov/34298140
https://pubmed.ncbi.nlm.nih.gov/34298140