Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Jurij Trontelj"'
Autor:
Alja Štern, Matjaž Novak, Katja Kološa, Jurij Trontelj, Sonja Žabkar, Tjaša Šentjurc, Metka Filipič, Bojana Žegura
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116969- (2024)
Cannabidiol (CBD), a naturally occurring cyclic terpenoid found in Cannabis sativa L., is renowned for its diverse pharmacological benefits. Marketed as a remedy for various health issues, CBD products are utilized by patients as a supplementary ther
Externí odkaz:
https://doaj.org/article/772750ed5d9147868214f4ae55e77cf2
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 1040 (2024)
Food can change various physiological parameters along the gastrointestinal tract, potentially impacting postprandial drug absorption. It is thus important to consider different in vivo conditions during in vitro studies. Therefore, a novel dissoluti
Externí odkaz:
https://doaj.org/article/9625bc34eb29448c9753fce1e58a8519
Autor:
Boris Podobnik, Lenart Demšar, Lucija Šarc, Aleš Jerin, Joško Osredkar, Jurij Trontelj, Robert Roškar, Miran Brvar
Publikováno v:
Toxics, Vol 12, Iss 8, p 585 (2024)
Alcohol hangover (veisalgia) is a fairly common phenomenon. The pathogenesis of veisalgia is not understood and treatment has not yet been established. Occasionally, students take N-acetylcysteine (NAC) before binge drinking to alleviate hangover. Th
Externí odkaz:
https://doaj.org/article/4a4ec2013c3c4d5ab0fb40ac3e00fb1d
Autor:
Žiga Tkalec, Jean-Philippe Antignac, Nicole Bandow, Frederic M. Béen, Lidia Belova, Jos Bessems, Bruno Le Bizec, Werner Brack, German Cano-Sancho, Jade Chaker, Adrian Covaci, Nicolas Creusot, Arthur David, Laurent Debrauwer, Gaud Dervilly, Radu Corneliu Duca, Valérie Fessard, Joan O. Grimalt, Thierry Guerin, Baninia Habchi, Helge Hecht, Juliane Hollender, Emilien L. Jamin, Jana Klánová, Tina Kosjek, Martin Krauss, Marja Lamoree, Gwenaelle Lavison-Bompard, Jeroen Meijer, Ruth Moeller, Hans Mol, Sophie Mompelat, An Van Nieuwenhuyse, Herbert Oberacher, Julien Parinet, Christof Van Poucke, Robert Roškar, Anne Togola, Jurij Trontelj, Elliott J. Price
Publikováno v:
Environment International, Vol 186, Iss , Pp 108585- (2024)
The chemical burden on the environment and human population is increasing. Consequently, regulatory risk assessment must keep pace to manage, reduce, and prevent adverse impacts on human and environmental health associated with hazardous chemicals. S
Externí odkaz:
https://doaj.org/article/a954656f71ff4863bc29976d595b4f42
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 449 (2024)
Background: The antiepileptic drug lamotrigine (LTG) shows high pharmacokinetic variability due to genotype influence and concomitant use of glucuronidation inducers and inhibitors, both of which may be frequently taken by elderly patients. Our goal
Externí odkaz:
https://doaj.org/article/dd05856e79ab4bcbac59ae7f7fdb53f6
Autor:
Maja Zakošek Pipan, Sonja Prpar Mihevc, Malan Štrbenc, Urban Košak, Ilija German Ilić, Jurij Trontelj, Simon Žakelj, Stanislav Gobec, Darja Pavlin, Gregor Majdič
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Canine cognitive dysfunction (CCD) is common in aged dogs and has many similarities with Alzheimer’s disease. Unfortunately, like Alzheimer’s disease, CCD cannot be cured. In the present study, we treated dogs with CCD with our newly dev
Externí odkaz:
https://doaj.org/article/32c976e38cff4eb89133a4590bc3ef91
Autor:
Darja Gramec Skledar, Jurij Trontelj, Johanna Troberg, Tihomir Tomašič, Anamarija Zega, Moshe Finel, Lucija Peterlin Mašič
Publikováno v:
Data in Brief, Vol 22, Iss , Pp 977-986 (2019)
Bisphenol AF (BPAF) is in the body mainly metabolized to the corresponding bisphenol AF glucuronide (BPAF-G). While BPAF-G is not commercially available, enzyme-assisted synthesis of BPAF-G using the human recombinant enzyme UGT2A1, purification of B
Externí odkaz:
https://doaj.org/article/005491d1fbc345f3ba436414f8ef2983
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 369 (2022)
The RPMI 2650 and Calu-3 cell lines have been previously evaluated as models of the nasal and airway epithelial barrier, and they have demonstrated the potential to be used in drug permeation studies. However, limited data exist on the utilization of
Externí odkaz:
https://doaj.org/article/2e854b21b27446109b2360a57b193d4c
Autor:
Anja Kolarič, Maja Kokot, Martina Hrast, Matjaž Weiss, Irena Zdovc, Jurij Trontelj, Simon Žakelj, Marko Anderluh, Nikola Minovski
Publikováno v:
Antibiotics, Vol 10, Iss 7, p 862 (2021)
Herein, we report the design of a focused library of novel bacterial topoisomerase inhibitors (NBTIs) based on innovative mainly monocyclic right-hand side fragments active against DNA gyrase and Topo IV. They exhibit a very potent and wide range of
Externí odkaz:
https://doaj.org/article/3a9be81a740c4e36be2d85de170b35dd
Autor:
Žane Temova Rakuša, Robert Roškar, Anita Klančar Andrejc, Tina Trdan Lušin, Nataša Faganeli, Iztok Grabnar, Aleš Mrhar, Albin Kristl, Jurij Trontelj
Publikováno v:
International Journal of Analytical Chemistry, Vol 2019 (2019)
A simple, fast, and cost-effective LC-MS/MS method for quantification of rifampicin in human plasma was developed and fully validated. The plasma samples containing rifampicin and isotopically labelled internal standard rifampicin D8, were cleaned up
Externí odkaz:
https://doaj.org/article/1fc16eb82b664d9c940255043dc92af3