Výsledky vyhledávání - "Jurij Aguiar Zdovc"

Akademický článek

Ustekinumab Dosing Individualization in Crohn’s Disease Guided by a Population Pharmacokinetic–Pharmacodynamic Model

Autor: Jurij Aguiar Zdovc, Jurij Hanžel, Tina Kurent, Nejc Sever, Matic Koželj, Nataša Smrekar, Gregor Novak, Borut Štabuc, Erwin Dreesen, Debby Thomas, Tomaž Vovk, Barbara Ostanek, David Drobne, Iztok Grabnar

Publikováno v: Pharmaceutics, Vol 13, Iss 10, p 1587 (2021)

Ustekinumab is a monoclonal antibody used in Crohn’s disease (CD). Dose optimization in case of non-response and the role of pharmacokinetic–pharmacodynamic (PK-PD) monitoring remain unresolved dilemmas in clinical practice. We aimed to develop a

Externí odkaz: https://doaj.org/article/da2b1fcaede847e99d10755cafa7954d

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Population pharmacokinetics of cisplatin in small cell lung cancer patients guided with informative priors

Autor: Jurij Aguiar Zdovc, Mihaela Vaupotič, Gregor Marolt, Lea Knez, Renata Režonja Kukec, Tanja Čufer, Tomaž Vovk, Iztok Grabnar

Publikováno v: Cancer chemotherapy and pharmacology, str. 301-313 : Ilustr., Vol. 90, iss. 4, 2022
COBISS-ID: 25191424

Purpose: Cisplatin-etoposide treatment is recommended as a first line in small cell lung cancer patients (SCLC). However, the prognosis is poor and the dosing is not tailored beyond the body surface area, which is related with indeterminate cisplatin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4af9f8ebc889d7f4a74e1c9263d5dc0
https://doi.org/10.1007/s00280-022-04465-9

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Relative bioavailability enhancement of simvastatin via dry emulsion systems:comparison of spray drying and fluid bed layering technology

Autor: Mitja, Pohlen, Jurij, Aguiar Zdovc, Jurij, Trontelj, Janez, Mravljak, Mirjam, Gosenca Matjaž, Iztok, Grabnar, Tomaž, Snoj, Rok, Dreu

Publikováno v: European journal of pharmaceutics and biopharmaceutics, str. 228-239 : Ilustr., Vol. 172, 2022
COBISS-ID: 13176839

Comprehensive comparisons of similar lipid based drug delivery systems produced by different technologies are scarce. Spray drying and fluid bed layering technologies were compared with respect to the process and product characteristics of otherwise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756fbf09e14c7bfbfffefec86376717b
https://www.sciencedirect.com/science/article/pii/S0939641121003532?via=ihub