Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jurica, Novak"'
Autor:
Vadim E. Tseilikman, Olga B. Tseilikman, Vadim A. Shevyrin, Oleg N. Yegorov, Alexandr A. Epitashvili, Maxim R. Aristov, Marina N. Karpenko, Ilya A. Lipatov, Anton A. Pashkov, Maxim V. Shamshurin, Irina A. Buksha, Anna K. Shonina, Alexandra Kolesnikova, Vladislav A. Shatilov, Maxim S. Zhukov, Jurica Novak
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 2063 (2024)
Stress-related anxiety disorders and anxiety-like behavior in post-traumatic stress disorder (PTSD) are associated with altered neurocircuitry pathways, neurotransmitter systems, and the activities of monoamine and glucocorticoid-metabolizing enzymes
Externí odkaz:
https://doaj.org/article/41de71245ff548519f25ffe86af5d8c6
Publikováno v:
BioImpacts, Vol 13, Iss 5, Pp 373-382 (2023)
Introduction: Machine learning methods, coupled with a tremendous increase in computer power in recent years, are promising tools in modern drug design and drug repurposing. Methods: Machine learning predictive models, publicly available at chemosoph
Externí odkaz:
https://doaj.org/article/1f476e258737424c85544e1dd4ecd17b
Autor:
Vadim E. Tseilikman, Olga B. Tseilikman, Oleg N. Yegorov, Alina A. Brichagina, Marina N. Karpenko, David V. Tseilikman, Vladislav A. Shatilov, Maxim S. Zhukov, Jurica Novak
Publikováno v:
Nutrients, Vol 16, Iss 17, p 2856 (2024)
The medicinal properties of resveratrol have garnered increasing attention from researchers. Extensive data have been accumulated on its use in treating cardiovascular diseases, immune system disorders, cancer, neurological diseases, and behavioral d
Externí odkaz:
https://doaj.org/article/e79dbf7631184d70a605eb776a1a5552
Autor:
Vadim E. Tseilikman, Vladislav A. Shatilov, Maxim S. Zhukov, Irina A. Buksha, Alexandr E. Epitashvily, Ilya A. Lipatov, Maxim R. Aristov, Alexandr G. Koshelev, Marina N. Karpenko, Dmitrii S. Traktirov, Viktoriya A. Maistrenko, Mustapha Kamel, Alexey V. Buhler, Elena G. Kovaleva, Tatyana S. Kalinina, Anton A. Pashkov, Vadim V. Kon’kov, Jurica Novak, Olga B. Tseilikman
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14343 (2023)
Currently, the efficacy of drug therapy for post-traumatic stress disorder or PTSD leaves much to be desired, making nutraceutical support a promising avenue for treatment. Recent research has identified the protective effects of resveratrol in PTSD.
Externí odkaz:
https://doaj.org/article/196c260a1c7b450386af9c07e953b8e8
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10907 (2023)
Kyasanur Forest Disease virus (KFDV), a neglected human pathogenic virus, is a Flavivirus that causes severe hemorrhagic fever in humans. KFDV is transmitted to humans by the bite of the hard tick (Haemaphysalis spinigera), which acts as a reservoir
Externí odkaz:
https://doaj.org/article/8219ef1cd5134c77a960e56638df46d6
Autor:
Shivananada Kandagalla, Hrvoje Rimac, Krishnamoorthy Gurushankar, Jurica Novak, Maria Grishina, Vladimir Potemkin
Publikováno v:
PeerJ, Vol 10, p e13374 (2022)
Exploring potent herbal medicine candidates is a promising strategy for combating a pandemic in the present global health crisis. In Ayurveda (a traditional medicine system in India), Withania somnifera (WS) is one of the most important herbs and it
Externí odkaz:
https://doaj.org/article/ec4414ab6a1b4c7cbebf69d756bba7f9
Autor:
Vadim E. Tseilikman, Julia O. Fedotova, Olga B. Tseilikman, Jurica Novak, Marina N. Karpenko, Victoria A. Maistrenko, Svetlana S. Lazuko, Lyudmila E. Belyeva, Mustapha Kamel, Alexey V. Buhler, Elena G. Kovaleva
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9333 (2023)
Glucocorticoids are metabolized by the CYP3A isoform of cytochrome P450 and by 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1). Experimental data suggest that post-traumatic stress disorder (PTSD) is associated with an increase in hepatic 11β
Externí odkaz:
https://doaj.org/article/1a45995aa8f446e084e6e4a19ec1c05c
Autor:
Jurica Novak, Vadim E. Tseilikman, Olga B. Tseilikman, Svetlana S. Lazuko, Lyudmila E. Belyeva, Azam Rahmani, Julia Fedotova
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 251 (2023)
The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) is an NADPH-dependent reductase, responsible for the activation of cortisol by reducing cortisone. Resveratrol (RES), a type of natural polyphenol, is reported to be able to slow the pr
Externí odkaz:
https://doaj.org/article/50c556b4191743e8b6b23922cbb96711
Autor:
Shivananda Kandagalla, Maria Grishina, Jurica Novak, Hrvoje Rimac, B. S. Sharath, Vladimir Potemkin
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acac5944c46bb8c31f4bfe32360cfc6c
https://doi.org/10.1080/07391102.2023.2166120
https://doi.org/10.1080/07391102.2023.2166120
Autor:
Ankit Kumar Singh, Jurica Novak, Adarsh Kumar, Harshwardhan Singh, Suresh Thareja, Prateek Pathak, Maria Grishina, Amita Verma, Jagat Pal Yadav, Habibullah Khalilullah, Vikas Pathania, Hemraj Nandanwar, Mariusz Jaremko, Abdul-Hamid Emwas, Pradeep Kumar
Publikováno v:
RSC Advances. 12:30181-30200
The“RAS-RAF-MEK-ERK” pathway is an important signaling pathway in melanoma. BRAFV600E(70–90%) is the most common mutation in this pathway. BRAF inhibitors have four types of conformers: type I (aC-IN/DFG-IN), type II (aC-IN/DFG-OUT), type I1/2(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8c426c548d7f4c1f0091f8926e18b4
https://doi.org/10.1039/d2ra05751d
https://doi.org/10.1039/d2ra05751d