Intracellular trafficking and functional monitoring of miRNA delivery in glioblastoma using lipopolyplexes and the miRNA-ON RILES reporter system

Autor: Simion, Viorel, Henriet, Elodie, Juric, Viktorija, Aquino, Ruth, Loussouarn, Claire, Laurent, Yoan, Martin, Francisco, Midoux, Patrick, Garcion, Emmanuel, Pichon, Chantal, Baril, Patrick

Publikováno v: In Journal of Controlled Release 10 November 2020 327:429-443

Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist

Autor: Boccellato, Chiara, Kolbe, Emily, Peters, Nathalie, Juric, Viktorija, Fullstone, Gavin, Verreault, Maïté, Idbaih, Ahmed, Lamfers, Martine L. M., Murphy, Brona M., Rehm, Markus

Publikováno v: Cell Death and Disease, Vol 12, Iss 7, Pp 1-11 (2021)
Cell Death and Disease, 12(7):647. Nature Publishing Group
Cell Death and Disease
Cell Death and Disease, 2021, 12 (7), pp.647. ⟨10.1038/s41419-021-03927-x⟩
Cell Death & Disease
Cell Death and Disease, Nature Publishing Group, 2021, 12 (7), pp.647. ⟨10.1038/s41419-021-03927-x⟩

Due to the absence of curative treatments for glioblastoma (GBM), we assessed the efficacy of single and combination treatments with a translationally relevant 2nd generation TRAIL-receptor agonist (IZI1551) and the blood–brain barrier (BBB) permea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49f38849da932971929656795f50851
https://doaj.org/article/6a4ac0b248c54c42adf51267374c1262

Targeting MCL-1 Dependence in GBM Using Transcriptional CDK Inhibitors CYC065 and THZ1

Autor: Juric, Viktorija

Glioblastoma multiforme (GBM) is the most aggressive form of primary malignant brain tumours in adults, accounting for nearly 50% of all central nervous system (CNS) tumours and currently treated with surgery and aggressive chemo- and radiotherapy. M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11604511b6d0c1e0d13c0abfe550092c

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