Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Juri Gelovani-Tjuvajev"'
Autor:
Vladimir Ponomarev, Michael Doubrovin, Inna Serganova, Tatiana Beresten, Jelena Vider, Aleksander Shavrin, Ludmila Ageyeva, Julius Balatoni, Ronald Blasberg, Juri Gelovani Tjuvajev
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 3, Pp 245-254 (2003)
To optimize the sensitivity of imaging HSV1-tk/GFP reporter gene expression, a series of HSV1-tk/GFP mutants was developed with altered nuclear localization and better cellular enzymatic activity, compared to that of the native HSV1-tk/GFP fusion pro
Externí odkaz:
https://doaj.org/article/6942fa4e9c8044e586c1d5dbec090c88
Autor:
Vladimir Ponomarev, Michael Doubrovin, Clay Lyddane, Tatiana Beresten, Julius Balatoni, William Bornman, Ronald Finn, Timothy Akhurst, Steven Larson, Ronald Blasberg, Michel Sadelain, Juri Gelovani Tjuvajev
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 6, Pp 480-488 (2001)
A noninvasive method for molecular imaging of T-cell activity in vivo would be of considerable value. It would aid in understanding the role of specific genes and signal transduction pathways in the course of normal and pathologic immune responses, c
Externí odkaz:
https://doaj.org/article/7041a0c094e34993ba84cd45c0f9875e
Publikováno v:
Molecular Imaging, Vol 1 (2002)
Molecular imaging is a relatively new discipline, which developed over the past decade, initially driven by in situ reporter imaging technology. Noninvasive in vivo molecular–genetic imaging developed more recently and is based on nuclear (positron
Externí odkaz:
https://doaj.org/article/581a007bfe6b4931b21b84dc4eed530d
Autor:
Trevor Hackman, Michail Doubrovin, Julius Balatoni, Tatiana Beresten, Vladimir Ponomarev, Bradly Beattie, Ronald Finn, William Bornmann, Ronald Blasberg, Juri Gelovani Tjuvajev
Publikováno v:
Molecular Imaging, Vol 1 (2002)
Double prodrug activation gene therapy using the Escherichia coli cytosine deaminase (CD)herpes simplex virus type 1 thymidine kinase ( HSV1-tk ) fusion gene ( CD/TK ) with 5-fluorocytosine (5FC), ganciclovir (GCV), and radiotherapy is currently unde
Externí odkaz:
https://doaj.org/article/37c466b4fb1b404bb94006eec5e95014
Autor:
Steven M. Larson, Mikhail Doubrovin, Juri Gelovani Tjuvajev, Tim Akhurst, Jason A. Koutcher, Joseph R. Bertino, Ronald D. Finn, Niraj J. Gusani, Ronald G. Blasberg, Debabrata Banerjee, Julius Balatoni, Philipp Mayer-Kuckuk, Yuman Fong, Terence P. Gade
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 30:1281-1291
Radionuclide imaging has been demonstrated to be feasible to monitor transgene expression in vivo. We hypothesized that a potential application of this technique is to non-invasively detect in deep tissue, such as cancer cells metastatic to the liver
Autor:
Ludmila Ageyeva, Julius Balatoni, Juri Gelovani Tjuvajev, Michael Doubrovin, Tatiana Beresten, Ronald G. Blasberg, Jelena Vider, Inna Serganova, Vladimir Ponomarev, Aleksander Shavrin
Publikováno v:
Scopus-Elsevier
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 3, Pp 245-254 (2003)
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 3, Pp 245-254 (2003)
To optimize the sensitivity of imaging HSV1-tk/GFP reporter gene expression, a series of HSV1-tk/GFP mutants was developed with altered nuclear localization and better cellular enzymatic activity, compared to that of the native HSV1-tk/GFP fusion pro
Publikováno v:
Journal of Cellular Biochemistry. 87:172-183
Noninvasive in vivo molecular-genetic imaging has developed over the past decade and involves nuclear (PET, gamma camera), magnetic resonance, and in vivo optical imaging systems. Although three different imaging strategies - "direct," "indirect" and
Autor:
Juri Gelovani Tjuvajev, Michail Doubrovin, Trevor Hackman, Vladimir Ponomarev, Julius Balatoni, Bradly Beattie, William Bornmann, Ronald D. Finn, Tatiana Beresten, Ronald G. Blasberg
Publikováno v:
Memorial Sloan Kettering Cancer Center
Double prodrug activation gene therapy using the Escherichia coli cytosine deaminase (CD)herpes simplex virus type 1 thymidine kinase ( HSV1-tk) fusion gene ( CD/TK) with 5-fluorocytosine (5FC), ganciclovir (GCV), and radiotherapy is currently under
Autor:
Ronald D. Finn, Michel Sadelain, Michael Doubrovin, Tatiana Beresten, Ronald G. Blasberg, Julius Balatoni, Steven M. Larson, Clay Lyddane, William Bornman, Tim Akhurst, Juri Gelovani Tjuvajev, Vladimir Ponomarev
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 6, Pp 480-488 (2001)
A noninvasive method for molecular imaging of T-cell activity in vivo would be of considerable value. It would aid in understanding the role of specific genes and signal transduction pathways in the course of normal and pathologic immune responses, c
Autor:
Bradley J. Beattie, Juri Gelovani Tjuvajev, Lauren D. Stegman, Els Kievit, Alnawaz Rehemtulla, Theodore S. Lawrence, Brian D. Ross, Ronald G. Blasberg
Publikováno v:
Proceedings of the National Academy of Sciences. 96:9821-9826
Analysis of transgene expression in vivo currently requires destructive and invasive molecular assays of tissue specimens. Noninvasive methodology for assessing the location, magnitude, and duration of transgene expression in vivo will facilitate sub