Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jurgen Meier"'
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 101790- (2023)
Externí odkaz:
https://doaj.org/article/a3f629d8a4b04b94b0afed18db8cc954
Publikováno v:
Brain Pathol
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurological disorder of multiple etiologies that affects primarily motor neurons in the brain and spinal cord. Abnormal accumulations of neurofilaments (NFs) in motor neurons and a down-regulatio
Autor:
Anna Stieber, Jacqueline O. Gonatas, Jean-Pierre Julien, Nicholas K. Gonatas, Peter Schweitzer, Jurgen Meier, Jean-Francois Collard
Publikováno v:
Journal of the neurological sciences. 173(1)
Fragmentation of the Golgi apparatus (GA) of motor neurons was first described in sporadic amyotrophic lateral sclerosis (ALS) and later confirmed in transgenic mice expressing the G93A mutation of the gene encoding the enzyme Cu,Zn superoxide dismut
Publikováno v:
Journal of neuropathology and experimental neurology. 58(10)
Previous studies demonstrated that transgenic mice overexpressing human neurofilament heavy (hNF-H) protein develop a progressive motor neuron disease characterized by the perikaryal accumulations of neurofilaments resembling those found in amyotroph
Publikováno v:
ECS Meeting Abstracts. :294-294
not Available.
Publikováno v:
Neurobiology of Disease, Vol 7, Iss 4, Pp 462-470 (2000)
A recent report by T. L. Williamson et al. (1998, Proc. Natl. Acad. Sci. USA 95, 9631–9636) showed that disease caused by expression of mutant Cu,Zn superoxide dismutase (SOD1) in mice was slowed down by disruption of the neurofilament light (NF-L)
Externí odkaz:
https://doaj.org/article/d23737e94d9242019bba5236cea4c6f1