Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jurgen Engel"'
Publikováno v:
Plants, Vol 13, Iss 19, p 2772 (2024)
Green leaf volatiles (GLVs) are important signaling compounds that help to regulate plant defenses against pests and pathogens. Made through the hydroperoxide lyase (HPL) pathway, they are rapidly produced upon damage and can signal to other parts of
Externí odkaz:
https://doaj.org/article/cced75a55be3451ba0d1794ff5886f53
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background The chemokines, CXCL12 and CXCL11, are upregulated in tumors from many organs and control their progression. CXCL12 and CXCL11 affect tumor cell functions by either binding their prime receptors, CXCR4 and CXCR3, respectively, and
Externí odkaz:
https://doaj.org/article/c6ae4b52226745b79fcc4bf3beea9fc9
First-time-in-man and pharmacokinetic study of weekly oral perifosine in patients with solid tumours
Autor:
Klaus Mross, Jurgen Engel, Herbert Sindermann, Axel-R. Hanauske, Wolfgang E. Berdel, Clemens Unger
Publikováno v:
European Journal of Cancer. 46:920-925
Aim To identify the maximum-tolerated dose (MTD) and pharmacokinetics of oral perifosine. Methods Patients with solid tumours received perifosine at dosages ranging from 100–800 mg/week. Eligibility criteria included life expectancy > 12 weeks, WHO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9825ab6ba79a9eb3ce85682fd40b6f22
https://doi.org/10.1016/j.ejca.2009.12.028
https://doi.org/10.1016/j.ejca.2009.12.028
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/17aa99f0aae04ec9b2f7dc4f09d13f3f
Autor:
E. Schickaneder, R. Mueller, H. Reile, Margaretha Jennerwein, Jurgen Engel, H. Schoenenberger, Thilo Spruss
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22dfa18d9b72591d8bb8d38b0440e357
https://doi.org/10.1002/chin.199147235
https://doi.org/10.1002/chin.199147235
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 116:439-442
D-19466, a new platinum complex, was characterized. It showed no nephrotoxic side-effects as determined by the measurement of blood urea. It was cytotoxic in vitro for tumor cells in concentrations comparable to or lower than cytotoxic concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee124115c757ed02784cfa589cbdcbd
https://doi.org/10.1007/bf01612990
https://doi.org/10.1007/bf01612990
Autor:
Jurgen Engel, Thilo Spruß, Helmut Schönenberger, Günther Bernhardt, Richard Müller, Ronald Gust, Herta Reile
Publikováno v:
Archiv der Pharmazie. 323:301-306
Diastereomeric diaqua[1,2-bis(4-fluorophenyl)ethylenediamine]platinum(II) sulfates and nitrates produce a strong inhibition of the hormone-dependent MXT-M 3.2 mammary carcinoma of the B6D2F1 mouse. Besides an interference in the DNA synthesis in anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::feeaa93e18349c7ccdbf0d864bba2514
https://doi.org/10.1002/ardp.19903230509
https://doi.org/10.1002/ardp.19903230509
Publikováno v:
Archiv der Pharmazie. 323:121-124
The synthesis of the bis-acrylate 12, the bis-β-chloropropionate 13 and the bis-β-bromopropionate 14 of the “partial” antiestrogen 2,3-bis(2-fluoro-4-hydroxyphenyl)-2,3-dimethylbutane (7) is described. In the case of 13 and 14 the introduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e2f2e4aa8402389a74f78bbde460ec
https://doi.org/10.1002/ardp.19903230213
https://doi.org/10.1002/ardp.19903230213
Miltefosine, an alkylphosphocholine structurally related to alkyllysophospholipids showed highly selective antitumour activity against the hormone-sensitive variant of the s.c. transplantable MXT mouse mammary adenocarcinoma, the ovary-dependent MXT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6486a869785fbb94b98d5c3e18ac40c
Autor:
Siegfried Seeber, Jurgen Engel, Günther Bernhardt, Helmut Schönenberger, Margaretha Jennerwein, Reiner Laske, R. Osieka, Walter Krischke, Herta Reile, Ronald Gust, Thilo Spruß, Richard Müller
Publikováno v:
Archiv der Pharmazie. 323(3)
Experiments on the P 388 D1 cell line (48 h exposure) demonstrate that [1,2-bis-(fluorophenyl)ethylenediamine]platinum(II) complexes are comparably active on the cell number and 3H-thymidine incorporation, irrespective of the position of the fluorine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e769542858626d7b1353fe34a9edb6
https://pubmed.ncbi.nlm.nih.gov/2344259
https://pubmed.ncbi.nlm.nih.gov/2344259