Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Jurgen Behr"'
Autor:
S. Stoltefuß, G. Leuschner, K. Milger, T. Kauke, J. Götschke, T. Veit, A. Lenoir, N. Kneidinger, Jürgen Behr
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background The R-Scale-PF was proposed to evaluate the health-related quality of life (HRQoL) in patients with idiopathic pulmonary fibrosis (IPF). We generated a German version of the R-Scale-PF (GR-Scale), representing the first translatio
Externí odkaz:
https://doaj.org/article/408b0bcf8a6b4316aae6308982c592d0
Autor:
Senem Ntourmas, Martin Sachs, Petra Paclíková, Martina Brückner, Vítězslav Bryja, Jürgen Behrens, Dominic B Bernkopf
Publikováno v:
eLife, Vol 13 (2024)
Activation of the Wnt/β-catenin pathway crucially depends on the polymerization of dishevelled 2 (DVL2) into biomolecular condensates. However, given the low affinity of known DVL2 self-interaction sites and its low cellular concentration, it is unc
Externí odkaz:
https://doaj.org/article/d5b61e976be743fca0a2384c105e1095
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 12, Pp 100719- (2024)
HER2 mutation and amplification have been identified as distinct molecular targets in lung cancer with different therapeutic and prognostic values. The coexistence of HER2 and EGFR mutations is extremely rare, and therefore, no data exist on the best
Externí odkaz:
https://doaj.org/article/2d970efa183942f79af2ce5c962b4b3a
Autor:
Franziska C. Trudzinski, Rudolf A. Jörres, Peter Alter, Henrik Watz, Claus F. Vogelmeier, Hans-Ulrich Kauczor, Subasini Thangamani, Manuel Debic, Tobias Welte, Jürgen Behr, Kathrin Kahnert, Robert Bals, Christian Herr, Claus Peter Heußel, Jürgen Biederer, Oyunbileg von Stackelberg, Sebastian Fähndrich, Emiel F. M. Wouters, Benjamin Waschki, Klaus F. Rabe, Felix J. F. Herth, Viktoria Palm, COSYCONET study group
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Patients with COPD are often affected by loss of bone mineral density (BMD) and osteoporotic fractures. Natriuretic peptides (NP) are known as cardiac markers, but have also been linked to fragility-associated fractures in the eld
Externí odkaz:
https://doaj.org/article/adadd9ca5c334e58ae95cbe9771279f4
Autor:
Steven D Nathan, Jurgen Behr, Vincent Cottin, Lisa Lancaster, Peter Smith, CQ Deng, Natalie Pearce, Heidi Bell, Leigh Peterson, Kevin R Flaherty
Publikováno v:
BMJ Open Respiratory Research. 9:e001310
IntroductionIdiopathic pulmonary fibrosis (IPF) greatly impacts quality of life and eventually leads to premature death from respiratory failure. Inhaled treprostinil was associated with improvements in forced vital capacity (FVC) and reduced exacerb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a292ab0f1bcc37c7ee8cf03ef3975d3f
https://doi.org/10.1136/bmjresp-2022-001310
https://doi.org/10.1136/bmjresp-2022-001310
Autor:
Moritz Z. Kayser, Hendrik Suhling, Jan Fuge, Christopher A. Hinze, Nora Drick, Nikolaus Kneidinger, Jürgen Behr, Christian Taube, Tobias Welte, Ina Haasler, Katrin Milger
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Monoclonal antibodies (biologics) drastically changed severe asthma therapy. Mepolizumab (anti-interleukin (IL) 5), benralizumab (anti-IL5 receptor alpha), and dupilumab (anti-IL4/13) are the most used biologics in this context. W
Externí odkaz:
https://doaj.org/article/9b65f82e70434ca195edfb5cf288a4e3
Autor:
Katharina Buschulte, Hans-Joachim Kabitz, Lars Hagmeyer, Peter Hammerl, Albert Esselmann, Conrad Wiederhold, Dirk Skowasch, Christoph Stolpe, Marcus Joest, Stefan Veitshans, Marc Höffgen, Phillen Maqhuzu, Larissa Schwarzkopf, Andreas Hellmann, Michael Pfeifer, Jürgen Behr, Rainer Karpavicius, Andreas Günther, Markus Polke, Philipp Höger, Vivien Somogyi, Christoph Lederer, Philipp Markart, Michael Kreuter
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Interstitial lung diseases (ILD) comprise a heterogeneous group of mainly chronic lung diseases with different disease trajectories. Progression (PF-ILD) occurs in up to 50% of patients and is associated with increased mortality.
Externí odkaz:
https://doaj.org/article/0daf0a7e2eff4281bcf049375a56f4e3
Autor:
Jennifer A. Zader, Rudolf A. Jörres, Imke Mayer, Peter Alter, Robert Bals, Henrik Watz, Pontus Mertsch, Klaus F. Rabe, Felix Herth, Franziska C. Trudzinski, Tobias Welte, Hans-Ulrich Kauczor, Jürgen Behr, Julia Walter, Claus F. Vogelmeier, Kathrin Kahnert
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Randomized controlled trials described beneficial effects of inhaled triple therapy (LABA/LAMA/ICS) in patients with chronic obstructive pulmonary disease (COPD) and high risk of exacerbations. We studied whether such effects were
Externí odkaz:
https://doaj.org/article/27c46972185c4c5da5640308713951a3
Autor:
Katharina Buschulte, Hans-Joachim Kabitz, Lars Hagmeyer, Peter Hammerl, Albert Esselmann, Conrad Wiederhold, Dirk Skowasch, Christoph Stolpe, Marcus Joest, Stefan Veitshans, Marc Höffgen, Phillen Maqhuzu, Larissa Schwarzkopf, Andreas Hellmann, Michael Pfeifer, Jürgen Behr, Rainer Karpavicius, Andreas Günther, Markus Polke, Philipp Höger, Vivien Somogyi, Christoph Lederer, Philipp Markart, Michael Kreuter
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Interstitial lung diseases (ILD) comprise a heterogeneous group of mainly chronic lung diseases with more than 200 entities and relevant differences in disease course and prognosis. Little data is available on hospitalisation patt
Externí odkaz:
https://doaj.org/article/77c5d81ca5334e7f8d52faa112bee379
Autor:
Thomas Melzer, Caroline Maria Hackl, Julia Walter, Jürgen Behr, Amanda Tufman, Pontus Mertsch, Diego Erich Kauffmann-Guerrero, Kathrin Kahnert
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-6 (2023)
Abstract As a result of advances in the treatment of lung cancer, the life expectancy of lung cancer patients has improved significantly, but it remains the leading cause of cancer death worldwide. For decades, most of the initial tumor biopsies have
Externí odkaz:
https://doaj.org/article/c160f4dd2500420fa8a6e5c338aca435