Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Jurga L"'
Autor:
Kaisa Hofwimmer, Joyce de Paula Souza, Narmadha Subramanian, Milica Vujičić, Leila Rachid, Hélène Méreau, Cheng Zhao, Erez Dror, Emelie Barreby, Niklas K. Björkström, Ingrid Wernstedt Asterholm, Marianne Böni-Schnetzler, Daniel T. Meier, Marc Y. Donath, Jurga Laurencikiene
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Postprandial IL-1β surges are predominant in the white adipose tissue (WAT), but its consequences are unknown. Here, we investigate the role of IL-1β in WAT energy storage and show that adipocyte-specific deletion of IL-1 receptor 1 (IL1R1
Externí odkaz:
https://doaj.org/article/ba5db9b693c1401681bcd5953d8aed76
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Salt-inducible kinase 2 (SIK2) is highly expressed in white adipocytes, but downregulated in individuals with obesity and insulin resistance. These conditions are often associated with a low-grade inflammation in adipose tissue. We and other
Externí odkaz:
https://doaj.org/article/7df1de0e02e042cbae75eb99432fa9bd
Autor:
Narmadha Subramanian, Kaisa Hofwimmer, Beatriz Tavira, Lucas Massier, Daniel P Andersson, Peter Arner, Jurga Laurencikiene
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-15 (2023)
Abstract Aim Obesity is linked to cardiometabolic diseases, however non-obese individuals are also at risk for type 2 diabetes (T2D) and cardiovascular disease (CVD). White adipose tissue (WAT) is known to play a role in both T2D and CVD, but the con
Externí odkaz:
https://doaj.org/article/046a15b794304227b1bec7ebfb0d45cf
Autor:
Lucas Massier, Jutta Jalkanen, Merve Elmastas, Jiawei Zhong, Tongtong Wang, Pamela A. Nono Nankam, Scott Frendo-Cumbo, Jesper Bäckdahl, Narmadha Subramanian, Takuya Sekine, Alastair G. Kerr, Ben T. P. Tseng, Jurga Laurencikiene, Marcus Buggert, Magda Lourda, Karolina Kublickiene, Nayanika Bhalla, Alma Andersson, Armand Valsesia, Arne Astrup, Ellen E. Blaak, Patrik L. Ståhl, Nathalie Viguerie, Dominique Langin, Christian Wolfrum, Matthias Blüher, Mikael Rydén, Niklas Mejhert
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Single-cell studies of human white adipose tissue (WAT) provide insights into the specialized cell types in the tissue. Here the authors combine publicly available and newly generated high-resolution and bulk transcriptomic results from multiple huma
Externí odkaz:
https://doaj.org/article/403c68977c1d4356b1c8f7dee3850e20
Autor:
Narmadha Subramanian, Kaisa Hofwimmer, Beatriz Tavira, Lucas Massier, Daniel P. Andersson, Peter Arner, Jurga Laurencikiene
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/f6ea70c24f874ed78378a8684475b6f2
Autor:
A Dammak, Vasilenková I, Labudová, Nádaská O, Migašová M, Grmanová E, Skarbová, Najšelová E, Dienerová M, Jurga L, Cingelová S, Berkešová D, Viktorínová Z
Publikováno v:
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti. 27(5)
INTRODUCTION Identification of new prognostic factors can help in designing future clinical studies. In the case of advanced non-small cell lung cancer, there might be good candidates - tumor markers CYFRA 21-1, CEA or NSE [1-8]. It is possible to ev
Autor:
Narmadha Subramanian, Beatriz Tavira, Kaisa Hofwimmer, Beate Gutsmann, Lucas Massier, Julie Abildgaard, Anders Juul, Mikael Rydén, Peter Arner, Jurga Laurencikiene
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundObesity-associated metabolic complications display sexual dimorphism and can be impacted by cytokines. We previously showed that interleukin-10 (IL-10) was upregulated in white adipose tissue (WAT) of obese women with type 2 diabetes (T2D).
Externí odkaz:
https://doaj.org/article/981085db62a14ba8a673bc2208419650
Autor:
Julia Sánchez-Ceinos, Rocío Guzmán-Ruiz, Oriol Alberto Rangel-Zúñiga, Jaime López-Alcalá, Elena Moreno-Caño, Mercedes Del Río-Moreno, Juan Luis Romero-Cabrera, Pablo Pérez-Martínez, Elsa Maymo-Masip, Joan Vendrell, Sonia Fernández-Veledo, José Manuel Fernández-Real, Jurga Laurencikiene, Mikael Rydén, Antonio Membrives, Raul M Luque, José López-Miranda, María M Malagón
Publikováno v:
eLife, Vol 10 (2021)
Preadipocytes are crucial for healthy adipose tissue expansion. Preadipocyte differentiation is altered in obese individuals, which has been proposed to contribute to obesity-associated metabolic disturbances. Here, we aimed at identifying the pathog
Externí odkaz:
https://doaj.org/article/af1e565ee14b40e49f3a99c51d6ad84c
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