Highly Efficient Targeting of EGFR-Expressing Tumor Cells with UniCAR T Cells via Target Modules Based on Cetuximab^®.

Autor: Jureczek, Justyna (AUTHOR), Feldmann, Anja (AUTHOR), Bergmann, Ralf (AUTHOR), Arndt, Claudia (AUTHOR), Berndt, Nicole (AUTHOR), Koristka, Stefanie (AUTHOR), Loureiro, Liliana Rodrigues (AUTHOR), Mitwasi, Nicola (AUTHOR), Hoffmann, Anja (AUTHOR), Kegler, Alexandra (AUTHOR), Bartsch, Tabea (AUTHOR), Bachmann, Michael (AUTHOR)

Publikováno v: OncoTargets & Therapy. Jun2020, Vol. 13, p5515-5527. 13p.

Highly Efficient Targeting of EGFR-Expressing Tumor Cells with UniCAR T Cells via Target Modules Based on Cetuximab®

Autor: Jureczek, Justyna, Feldmann, Anja, Bergmann, Ralf, Arndt, Claudia, Berndt, Nicole, Koristka, Stefanie, Loureiro, Liliana Rodrigues, Mitwasi, Nicola, Hoffmann, Anja, Kegler, Alexandra, Bartsch, Tabea, Bachmann, Michael

Publikováno v: OncoTargets and therapy
OncoTargets and Therapy 13(2020), 5515-5527

Introduction: Since epithelial growth factor receptor (EGFR) overexpression is linked to a variety of malignancies, it is an attractive target for immune therapy including with chimeric antigen receptor (CAR)-engineered T cells. Unfortunately, CAR T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::13efd2656b3296a39013ae5bf59eeb01
http://europepmc.org/articles/PMC7297505

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Combinatorial tumor targeting using a novel switchable RevCAR system

Autor: Anja Feldmann, Hoffmann, Anja, Bergmann, Ralf, Loureiro, Liliana, Kittel-Boselli, Enrico, Mitwasi, Nicola, Koristka, Stefanie, Jureczek, Justyna, Berndt, Nicole, Arndt, Claudia, Bachmann, Michael

Publikováno v: Journal for ImmunoTherapy of Cancer 7(2019)Suppl. 1, P174
Publons
34th Annual Meeting of the Society for Immunotherapy of Cancer (SITC 2019), 06.-10.11.2019, National Harbor, Maryland, USA

Background Although T-cells genetically modified to express chimeric antigen receptors (CARs) are successfully used to treat hematological malignancies, patients still suffer from several drawbacks of conventional CAR (cCAR) therapy. CAR-T-cells can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::483878be6247cb7311b999c39d87cfe1
https://www.hzdr.de/publications/Publ-30169-1

Highly Efficient Targeting of EGFR-Expressing Tumor Cells with UniCAR T Cells via Target Modules Based on Cetuximab^®.

Autor: Jureczek, Justyna, Feldmann, Anja, Bergmann, Ralf, Arndt, Claudia, Berndt, Nicole, Koristka, Stefanie, Loureiro, Liliana Rodrigues, Mitwasi, Nicola, Hoffmann, Anja, Kegler, Alexandra, Bartsch, Tabea, Bachmann, Michael

Publikováno v: OncoTargets & Therapy; Jun2020, Vol. 13, p5515-5527, 13p