P19-49. Modulation of vaccine induced responses through CTLA-4 and 41BB enhances protection in macaques following SIVmac251 challenge

Autor: Jure-Kunkel MN, Lewis M, Anderson H, Dai A, Boyer JD, Yan J, Weber J, Hokey DA, Hirao LA, Weiner DB

Publikováno v: Retrovirology, Vol 6, Iss Suppl 3, p P369 (2009)

Externí odkaz: https://doaj.org/article/301176e65ee34a5f8efb02b07c27a1eb

Synthesis and biological evaluation of biaryl alkyl ethers as inhibitors of IDO1.

Autor: Markwalder JA; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, NJ 08543, United States. Electronic address: itr114@gmail.com., Balog AJ; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, NJ 08543, United States., Williams DK; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, NJ 08543, United States. Electronic address: david.williams@bms.com., Nara SJ; Discovery Chemistry, Biocon Bristol Myers Squibb Research & Development Center, Bangalore, India., Reddy R; Discovery Chemistry, Biocon Bristol Myers Squibb Research & Development Center, Bangalore, India., Roy S; Former Bristol Myers Squibb Employee, United States., Kanyaboina Y; Discovery Chemistry, Biocon Bristol Myers Squibb Research & Development Center, Bangalore, India., Li X; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, NJ 08543, United States., Johnston K; Former Bristol Myers Squibb Employee, United States., Fan Y; Former Bristol Myers Squibb Employee, United States., Lewis H; Former Bristol Myers Squibb Employee, United States., Marsilio F; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, NJ 08543, United States., Yan C; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, NJ 08543, United States., Critton D; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, NJ 08543, United States., Newitt JA; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, NJ 08543, United States., Traeger SC; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, NJ 08543, United States., Wu DR; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, NJ 08543, United States., Jure-Kunkel MN; Former Bristol Myers Squibb Employee, United States., Jayaraman L; Former Bristol Myers Squibb Employee, United States., Lin TA; Former Bristol Myers Squibb Employee, United States., Sinz MW; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, NJ 08543, United States., Hunt JT; Former Bristol Myers Squibb Employee, United States., Seitz SP; Former Bristol Myers Squibb Employee, United States.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2023 May 15; Vol. 88, pp. 129280. Date of Electronic Publication: 2023 Apr 11.

Identification and optimization of a novel series of indoleamine 2,3-dioxygenase inhibitors.

Autor: Markwalder JA; Oncology Chemistry, Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-5400, United States. Electronic address: jay.markwalder@bms.com., Seitz SP; Oncology Chemistry, Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-5400, United States., Blat Y; Mechanistic Biochemistry, Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-5400, United States., Elkin L; Lead Discovery & Optimization, Bristol-Myers Squibb Research and Development, Wallingford, CT 06492, United States., Hunt JT; Oncology Biology, Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-5400, United States., Pabalan JG; Oncology Biology, Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-5400, United States., Jure-Kunkel MN; Oncology Biology, Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-5400, United States., Vite GD; Oncology Chemistry, Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-5400, United States., Covello K; Oncology Biology, Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-5400, United States.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2017 Feb 01; Vol. 27 (3), pp. 582-585. Date of Electronic Publication: 2016 Dec 07.

Immune modulation through 4-1BB enhances SIV vaccine protection in non-human primates against SIVmac251 challenge.

Autor: Hirao LA; University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Hokey DA, Morrow MP, Jure-Kunkel MN, Weiner DB

Publikováno v: PloS one [PLoS One] 2011; Vol. 6 (9), pp. e24250. Date of Electronic Publication: 2011 Sep 15.

Cloning, expression and characterization of monkey (Macaca fascicularis) CD137.

Autor: Chen SJ; Discovery Toxicology, Bristol-Myers Squibb Research and Development, Route 206 & Province Line Road, Princeton, NJ 08543, United States. shenjue.chen@bms.com, Foster WR, Jure-Kunkel MN, Girit E, Abraham R, Hefta LJ, Gao S, Yonan CR, Lin JH, Dambach DM

Publikováno v: Veterinary immunology and immunopathology [Vet Immunol Immunopathol] 2008 Dec 15; Vol. 126 (3-4), pp. 377-81. Date of Electronic Publication: 2008 Jul 31.