Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jure Mur"'
Autor:
Sascha Zuber, Laura Bechtiger, Julien Stéphane Bodelet, Marta Golin, Jens Heumann, Jung Hyun Kim, Matthias Klee, Jure Mur, Jennie Noll, Stacey Voll, Patrick O’Keefe, Annekatrin Steinhoff, Ulf Zölitz, Graciela Muniz-Terrera, Lilly Shanahan, Michael J. Shanahan, Scott M. Hofer
Publikováno v:
Discover Social Science and Health, Vol 3, Iss 1, Pp 1-20 (2023)
Abstract Life course epidemiology seeks to understand the intricate relationships between risk factors and health outcomes across different stages of life to inform prevention and intervention strategies to optimize health throughout the lifespan. Ho
Externí odkaz:
https://doaj.org/article/effe0edd1d704946b0be37b680fa378c
Publikováno v:
International Journal of Population Data Science, Vol 7, Iss 3 (2022)
Background Anticholinergic drugs block muscarinic receptors in the body. They are commonly prescribed for a variety of indications and their use has previously been associated with dementia and cognitive decline. Methods In UK Biobank participants
Externí odkaz:
https://doaj.org/article/6ed7cc9d55864574921b9258e1ca15b8
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Background Previous studies on the relationship between anticholinergic drugs and dementia have reported heterogeneous results. This variability could be due to different anticholinergic scales and differential effects of distinct classes of
Externí odkaz:
https://doaj.org/article/3f6f8ca98f194a85879d64232fdb9790
Autor:
Jure Mur, Daniel L. McCartney, Rosie M. Walker, Archie Campbell, Mairead L. Bermingham, Stewart W. Morris, David J. Porteous, Andrew M. McIntosh, Ian J. Deary, Kathryn L. Evans, Riccardo E. Marioni
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Genetic variation in the apolipoprotein E (APOE) gene is associated with Alzheimer's disease (AD) and risk factors for cardiovascular disease (CVD). DNA methylationat APOE has been associated with altered cognition and AD. It is
Externí odkaz:
https://doaj.org/article/5172636bc2d5431986eb00d7915f752b
Publikováno v:
Mur, J, Marioni, R E, Russ, T C, Muniz-Terrera, G & Cox, S R 2023, ' Anticholinergic burden in middle and older age is associated with lower cognitive function, but not with brain atrophy ', British Journal of Clinical Pharmacology . https://doi.org/10.1111/bcp.15698
AIMS: The aim of this study is to estimate the association between anticholinergic burden, general cognitive ability and various measures of brain structural MRI in relatively healthy middle-aged and older individuals.METHODS: In the UK Biobank parti
Publikováno v:
Mur, J, Russ, T, Cox, S R, Marioni, R E & Terrera, GM 2022, ' Association between anticholinergic burden and dementia in UK Biobank ', Alzheimer's and Dementia: Translational Research and Clinical Interventions, vol. 8, no. 1, e12290, pp. e12290 . https://doi.org/10.1002/trc2.12290
Innovation in Aging
Innovation in Aging
Previous studies on the association between the long-term use of anticholinergic drugs and dementia report heterogenous results. This variability could be due to, among other factors, different anticholinergic scales used, and differential effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f0c118014db9fcebf0e76868fc5405
https://doi.org/10.1101/2021.08.04.21261330
https://doi.org/10.1101/2021.08.04.21261330
Publikováno v:
Mur, J, Cox, S R, Marioni, R E, Muniz-Terrera, G & Russ, T C 2021, ' Increase in anticholinergic burden from 1990 to 2015 : Aage-period-cohort analysis in UK Biobank ', British Journal of Clinical Pharmacology . https://doi.org/10.1111/bcp.15045
BackgroundThe use of prescription drugs with anticholinergic properties has been associated with multiple negative health outcomes in older people. Moreover, recent evidence suggests that associated adverse effects may occur even decades after stoppi
BackgroundThe use of prescription drugs with anticholinergic properties has been associated with multiple negative health outcomes in older people. Moreover, recent evidence suggests that associated adverse effects may occur even decades after stoppi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44679ae5d4c81160bcda138895c81a74
https://doi.org/10.1101/2020.10.16.20213884
https://doi.org/10.1101/2020.10.16.20213884
Autor:
Archie Campbell, Ian J. Deary, Andrew M. McIntosh, Riccardo E. Marioni, Rosie M. Walker, Kathryn L. Evans, Daniel L. McCartney, Jure Mur, Mairead L. Bermingham, Stewart W. Morris, David J. Porteous
Publikováno v:
Mur, J, McCartney, D L, Walker, R, Campbell, A, Bermingham, M, Morris, S, Porteous, D, McIntosh, A, Deary, I, Evans, K & Marioni, R 2020, ' DNA methylation in APOE : The relationship with Alzheimer’s and with cardiovascular health ', Alzheimer's and Dementia: Translational Research and Clinical Interventions, vol. 6, no. 1 . https://doi.org/10.1002/trc2.12026
Mur, J, Mccartney, D L, Walker, R M, Campbell, A, Bermingham, M L, Morris, S W, Porteous, D J, Mcintosh, A M, Deary, I J, Evans, K L & Marioni, R E 2020, ' DNA methylation in APOE: The relationship with Alzheimer's and with cardiovascular health ', Alzheimer's and Dementia: Translational Research and Clinical Interventions, vol. 6, no. 1 . https://doi.org/10.1002/trc2.12026
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Mur, J, Mccartney, D L, Walker, R M, Campbell, A, Bermingham, M L, Morris, S W, Porteous, D J, Mcintosh, A M, Deary, I J, Evans, K L & Marioni, R E 2020, ' DNA methylation in APOE: The relationship with Alzheimer's and with cardiovascular health ', Alzheimer's and Dementia: Translational Research and Clinical Interventions, vol. 6, no. 1 . https://doi.org/10.1002/trc2.12026
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Introduction Genetic variation in the apolipoprotein E (APOE) gene is associated with Alzheimer's disease (AD) and risk factors for cardiovascular disease (CVD). DNA methylationat APOE has been associated with altered cognition and AD. It is unclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857612a8a5f8ed71af6671d74894f758
https://hdl.handle.net/20.500.11820/08d0803f-a886-4522-9d46-3f2bc9e26a98
https://hdl.handle.net/20.500.11820/08d0803f-a886-4522-9d46-3f2bc9e26a98
Autor:
Jure Mur, Campbell A, Ian J. Deary, Andrew M. McIntosh, Mairead L. Bermingham, Kathryn L. Evans, Rosie M. Walker, David J. Porteous, Stewart W. Morris, Daniel L. McCartney, Riccardo E. Marioni
Genetic variation in the apolipoprotein E (APOE) gene is associated with Alzheimer’s disease (AD) and risk factors for cardiovascular disease (CVD). DNA methylation at APOE has been linked to altered cognition and AD. It is unclear if epigenetic ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d069633f4461a84b9b33fb91a8eec8c6
https://doi.org/10.1101/811224
https://doi.org/10.1101/811224