76P Highly potent fully human anti-VISTA antibodies efficiently abrogate the interaction of this new target checkpoint inhibitor to its different putative receptors at different pH

Autor: Iadonato, S., Tarcha, E., Bader, R., Dutzar, B., Eyde, N., Frazier, E., Jurchen, D., Lance, R., Loomis, C., Lustig, K., Ovechkina, Y., Peckham, D., Posakony, J., Sridhar, S., Xu, M., Guillaudeux, T.

Publikováno v: In Annals of Oncology December 2020 31 Supplement 7:S1448-S1449

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Pharmacologic Characterization of ALD1910, a Potent Humanized Monoclonal Antibody against the Pituitary Adenylate Cyclase-Activating Peptide.

Autor: Moldovan Loomis C; Alder BioPharmaceuticals, Inc., Bothell, Washington., Dutzar B; Alder BioPharmaceuticals, Inc., Bothell, Washington., Ojala EW; Alder BioPharmaceuticals, Inc., Bothell, Washington., Hendrix L; Alder BioPharmaceuticals, Inc., Bothell, Washington., Karasek C; Alder BioPharmaceuticals, Inc., Bothell, Washington., Scalley-Kim M; Alder BioPharmaceuticals, Inc., Bothell, Washington., Mulligan J; Alder BioPharmaceuticals, Inc., Bothell, Washington., Fan P; Alder BioPharmaceuticals, Inc., Bothell, Washington., Billgren J; Alder BioPharmaceuticals, Inc., Bothell, Washington., Rubin V; Alder BioPharmaceuticals, Inc., Bothell, Washington., Boshaw H; Alder BioPharmaceuticals, Inc., Bothell, Washington., Kwon G; Alder BioPharmaceuticals, Inc., Bothell, Washington., Marzolf S; Alder BioPharmaceuticals, Inc., Bothell, Washington., Stewart E; Alder BioPharmaceuticals, Inc., Bothell, Washington., Jurchen D; Alder BioPharmaceuticals, Inc., Bothell, Washington., Pederson SM; Alder BioPharmaceuticals, Inc., Bothell, Washington., Perrino McCulloch L; Alder BioPharmaceuticals, Inc., Bothell, Washington., Baker B; Alder BioPharmaceuticals, Inc., Bothell, Washington., Cady RK; Alder BioPharmaceuticals, Inc., Bothell, Washington., Latham JA; Alder BioPharmaceuticals, Inc., Bothell, Washington., Allison D; Alder BioPharmaceuticals, Inc., Bothell, Washington., Garcia-Martinez LF; Alder BioPharmaceuticals, Inc., Bothell, Washington lgarcia-martinez@alderbio.com.

Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2019 Apr; Vol. 369 (1), pp. 26-36. Date of Electronic Publication: 2019 Jan 14.