Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Juraj Stanik"'
Autor:
Kristina Podolakova, Lubomir Barak, Emilia Jancova, Simona Tarnokova, Ludmila Podracka, Zuzana Dobiasova, Martina Skopkova, Daniela Gasperikova, Juraj Stanik
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Little is known about complete remission in Type 1 diabetes mellitus (T1D) with the discontinuance of insulin treatment for a period of time. In this retrospective study we analysed the frequency and factors of onset and duration of 1. remis
Externí odkaz:
https://doaj.org/article/a1782293193f42c8add2061e0b80e967
Autor:
Elena Kempf, Kathrin Landgraf, Tim Vogel, Ulrike Spielau, Robert Stein, Matthias Raschpichler, Jürgen Kratzsch, Wieland Kiess, Juraj Stanik, Antje Körner
Publikováno v:
Adipocyte, Vol 11, Iss 1, Pp 630-642 (2022)
Components of the growth hormone (GH) axis, such as insulin-like growth factor-1 (IGF-1), IGF-1 binding protein-3 (IGFBP-3), GH receptor (GHR) and GH-binding protein (GHBP), regulate growth and metabolic pathways. Here, we asked if serum levels of th
Externí odkaz:
https://doaj.org/article/be35b0926008425ebe67fd1b7ae2ab04
Autor:
Elena Kempf, Mandy Vogel, Tim Vogel, Jürgen Kratzsch, Kathrin Landgraf, Andreas Kühnapfel, Ruth Gausche, Daniel Gräfe, Elena Sergeyev, Roland Pfäffle, Wieland Kiess, Juraj Stanik, Antje Körner
Publikováno v:
EClinicalMedicine, Vol 37, Iss , Pp 100977- (2021)
Background: Obesity can affect linear growth of children but there is uncertainty regarding the dynamics and potential causes. Methods: In the population-based LIFE Child and the obesity-enriched Leipzig Obesity Childhood cohorts (8,629 children, 37,
Externí odkaz:
https://doaj.org/article/54e14e4aae014e5693ee7f84d93a315d
Autor:
Dennis Löffler, Susanne Behrendt, John W.M. Creemers, Jürgen Klammt, Gabriela Aust, Juraj Stanik, Wieland Kiess, Peter Kovacs, Antje Körner
Publikováno v:
Molecular Metabolism, Vol 6, Iss 3, Pp 295-305 (2017)
Objective: Variants in Proprotein Convertase Subtilisin/Kexin Type 1 (PCSK1) may be causative for obesity as suggested by monogenic cases and association studies. Here we assessed the functional relevance in experimental studies and the clinical rele
Externí odkaz:
https://doaj.org/article/071b460c88ce41049a3b3e9cde0cd903
Autor:
Daniela Stanikova, Tobias Luck, Alexander Pabst, Yoon Ju Bae, Andreas Hinz, Heide Glaesmer, Juraj Stanik, Julia Sacher, Christoph Engel, Cornelia Enzenbach, Kerstin Wirkner, Uta Ceglarek, Joachim Thiery, Juergen Kratzsch, Steffi G. Riedel-Heller
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
Background: Several studies have shown a positive association between anxiety and obesity, particularly in women. We aimed to study whether sex hormone alterations related to obesity might play a role in this association.Patients and methods: Data fo
Externí odkaz:
https://doaj.org/article/94d0bac4d4a64a9c8526c5e8bb5435db
Autor:
Juraj Stanik, Jürgen Kratzsch, Kathrin Landgraf, Kathrin Scheuermann, Ulrike Spielau, Ruth Gausche, Daniela Gasperikova, Wieland Kiess, Antje Körner
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178107 (2017)
Leptin secreted from adipose tissue signals peripheral energy status to the brain. Monogenic leptin deficiency results in severe early onset obesity with hyperphagia. Recently, a similar phenotype of inactivating leptin mutations but with preserved i
Externí odkaz:
https://doaj.org/article/e213d7f74fbf40d3a4fcc74e15ef351b
Autor:
Daniela Stanikova, Marek Buzga, Patrik Krumpolec, Martina Skopkova, Martina Surova, Barbara Ukropcova, Lubica Ticha, Miroslava Petrasova, Dominika Gabcova, Miroslava Huckova, Lucie Piskorova, Jan Bozensky, Marian Mokan, Jozef Ukropec, Ivona Zavacka, Iwar Klimes, Juraj Stanik, Daniela Gasperikova
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177222 (2017)
BACKGROUND:Inactivating mutations of the hypothalamic transcription factor singleminded1 (SIM1) have been shown as a cause of early-onset severe obesity. However, to date, the contribution of SIM1 mutations to the obesity phenotype has only been stud
Externí odkaz:
https://doaj.org/article/c19e4cfce54d414c8a80a20dcd2a4f78
Autor:
Elena, Kempf, Kathrin, Landgraf, Tim, Vogel, Ulrike, Spielau, Robert, Stein, Matthias, Raschpichler, Jürgen, Kratzsch, Wieland, Kiess, Juraj, Stanik, Antje, Körner
Publikováno v:
Adipocyte. 11(1)
Components of the growth hormone (GH) axis, such as insulin-like growth factor-1 (IGF-1), IGF-1 binding protein-3 (IGFBP-3), GH receptor (GHR) and GH-binding protein (GHBP), regulate growth and metabolic pathways. Here, we asked if serum levels of th
Autor:
Maximiliane Chiara Hammel, Robert Stein, Jürgen Kratzsch, Mandy Vogel, Alexander J. Eckert, Rima Destya Triatin, Marco Colombo, Christof Meigen, Ronny Baber, Juraj Stanik, Ulrike Spielau, Anette Stoltze, Kerstin Wirkner, Anke Tönjes, Harold Snieder, Reinhard W. Holl, Michael Stumvoll, Matthias Blüher, Wieland Kiess, Antje Körner
Publikováno v:
The Lancet Regional Health - Europe. :100652
Autor:
Stanikova D, Daniela Gasperikova, I Trochanová, P Čižnár, Juraj Stanik, Martina Skopkova, K Haštová
Publikováno v:
Physiol Res
MEHMO syndrome is a rare X-linked syndrome characterized by Mental retardation, Epilepsy, Hypogenitalism, Microcephaly, and Obesity associated with the defect of protein synthesis caused by the EIF2S3 gene mutations. We hypothesized that the defect i