Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Juraj Kopacek"'
Autor:
Martin Benej, Eliska Svastova, Radivojka Banova, Juraj Kopacek, Adriana Gibadulinova, Martin Kery, Simona Arena, Andrea Scaloni, Monica Vitale, Nicola Zambrano, Ioanna Papandreou, Nicholas C. Denko, Silvia Pastorekova
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Tumor hypoxia represents a severe microenvironmental stress that is frequently associated with acidosis. Cancer cells respond to these stresses with changes in gene expression that promote survival at least in part through pH regulation and metabolic
Externí odkaz:
https://doaj.org/article/9b8010c39ef64e049616ebd117f253ef
Autor:
Sabina Strapcova, Martina Takacova, Lucia Csaderova, Paola Martinelli, Lubomira Lukacikova, Viliam Gal, Juraj Kopacek, Eliska Svastova
Publikováno v:
Cancers, Vol 12, Iss 8, p 2005 (2020)
Hypoxia is a common phenomenon that occurs in most solid tumors. Regardless of tumor origin, the evolution of a hypoxia-adapted phenotype is critical for invasive cancer development. Pancreatic ductal adenocarcinoma is also characterized by hypoxia,
Externí odkaz:
https://doaj.org/article/5029af1ff4cb4257ba8f5e65298e8c1e
Autor:
Martina Takacova, Monika Barathova, Miriam Zatovicova, Tereza Golias, Ivana Kajanova, Lenka Jelenska, Olga Sedlakova, Eliska Svastova, Juraj Kopacek, Silvia Pastorekova
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 246 (2019)
In contrast to human carbonic anhydrase IX (hCA IX) that has been extensively studied with respect to its molecular and functional properties as well as regulation and expression, the mouse ortholog has been investigated primarily in relation to tiss
Externí odkaz:
https://doaj.org/article/419e31ead78c43c2be05eb19e8e76d36
Autor:
Michaela Debreova, Lucia Csaderova, Monika Burikova, Lubomira Lukacikova, Ivana Kajanova, Olga Sedlakova, Martin Kery, Juraj Kopacek, Miriam Zatovicova, Jozef Bizik, Silvia Pastorekova, Eliska Svastova
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2745 (2019)
Tumor metastasis is tightly linked with invasive membrane protrusions, invadopodia, formed by actively invading tumor cells. Hypoxia and pH modulation play a role in the invadopodia formation and in their matrix degradation ability. Tumor-associated
Externí odkaz:
https://doaj.org/article/9f5a4d9de6754b9bb5ef577ef5eed845
Autor:
Jaromir Pastorek, Silvia Pastorekova, Claudiu T. Supuran, Juraj Kopacek, Lucia Csaderova, Miriam Zatovicova, Anna Ohradanova-Repic, Alzbeta Hulikova, Eliska Svastova, Franck Dequiedt, Peter Ditte
PDf file - 71K, List of primers used for cloning of phosphorylation mutants and CA IX-CA II and CA IX-CA XII chimeras. Boldcase sequences represent nucleotides aligning to CA IX part.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8b51bdfc5f064a8c19742835b77a69
https://doi.org/10.1158/0008-5472.22390062.v1
https://doi.org/10.1158/0008-5472.22390062.v1
Autor:
Jaromir Pastorek, Silvia Pastorekova, Claudiu T. Supuran, Juraj Kopacek, Lucia Csaderova, Miriam Zatovicova, Anna Ohradanova-Repic, Alzbeta Hulikova, Eliska Svastova, Franck Dequiedt, Peter Ditte
PDF file - 78K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391161955ecbb062b3238e262254f0b9
https://doi.org/10.1158/0008-5472.22390065.v1
https://doi.org/10.1158/0008-5472.22390065.v1
Autor:
Jaromir Pastorek, Silvia Pastorekova, Claudiu T. Supuran, Juraj Kopacek, Lucia Csaderova, Miriam Zatovicova, Anna Ohradanova-Repic, Alzbeta Hulikova, Eliska Svastova, Franck Dequiedt, Peter Ditte
PDf file - 1.2MB, CA IX co-localization with NBC1 in A549 cells is presented in the form of Z-stack corresponding to Figure 6B.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f6d051d272241a033f41f30b324275
https://doi.org/10.1158/0008-5472.22390074
https://doi.org/10.1158/0008-5472.22390074
Autor:
Jaromir Pastorek, Silvia Pastorekova, Claudiu T. Supuran, Juraj Kopacek, Lucia Csaderova, Miriam Zatovicova, Anna Ohradanova-Repic, Alzbeta Hulikova, Eliska Svastova, Franck Dequiedt, Peter Ditte
In the hypoxic regions of a tumor, carbonic anhydrase IX (CA IX) is an important transmembrane component of the pH regulatory machinery that participates in bicarbonate transport. Because tumor pH has implications for growth, invasion, and therapy, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3b9127e9a74d57452c6c9f100e30791
https://doi.org/10.1158/0008-5472.c.6502812.v1
https://doi.org/10.1158/0008-5472.c.6502812.v1
Autor:
Jaromir Pastorek, Silvia Pastorekova, Claudiu T. Supuran, Juraj Kopacek, Lucia Csaderova, Miriam Zatovicova, Anna Ohradanova-Repic, Alzbeta Hulikova, Eliska Svastova, Franck Dequiedt, Peter Ditte
PDf file - 72K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e0b477b600b6b1f006905817705588
https://doi.org/10.1158/0008-5472.22390068
https://doi.org/10.1158/0008-5472.22390068
Autor:
Jaromir Pastorek, Silvia Pastorekova, Claudiu T. Supuran, Juraj Kopacek, Lucia Csaderova, Miriam Zatovicova, Anna Ohradanova-Repic, Alzbeta Hulikova, Eliska Svastova, Franck Dequiedt, Peter Ditte
PDf file - 1.3MB, CA IX co-localization with PKA-phosphorylated substrates in A549 cells is presented in the form of Z-stack corresponding to Figure 6A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2131a09d476ca88c72bdd1d33c5e7748
https://doi.org/10.1158/0008-5472.22390077
https://doi.org/10.1158/0008-5472.22390077