Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Juraj Kokavec"'
Autor:
Tereza Turkova, Juraj Kokavec, Tomas Zikmund, Nikol Dibus, Kristyna Pimkova, Dusan Nemec, Marketa Holeckova, Livia Ruskova, Radislav Sedlacek, Lukas Cermak, Tomas Stopka
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract The formation of hematopoietic cells relies on the chromatin remodeling activities of ISWI ATPase SMARCA5 (SNF2H) and its complexes. The Smarca5 null and conditional alleles have been used to study its functions in embryonic and organ develo
Externí odkaz:
https://doaj.org/article/fbaf7798104b4faba24bcad1875a3d2d
Publikováno v:
HemaSphere, Vol 7, p e53556e3 (2023)
Externí odkaz:
https://doaj.org/article/ece6c2f856404eb289bbcef14b52e296
Autor:
Lubomír Minařík, Kristýna Pimková, Juraj Kokavec, Adéla Schaffartziková, Fréderic Vellieux, Vojtěch Kulvait, Lenka Daumová, Nina Dusilková, Anna Jonášová, Karina Savvulidi Vargová, Petra Králová Viziová, Radislav Sedláček, Zuzana Zemanová, Tomáš Stopka
Publikováno v:
Cells, Vol 11, Iss 2, p 223 (2022)
The mechanisms by which myelodysplastic syndrome (MDS) cells resist the effects of hypomethylating agents (HMA) are currently the subject of intensive research. A better understanding of mechanisms by which the MDS cell becomes to tolerate HMA and pr
Externí odkaz:
https://doaj.org/article/39a2027bf15f48a4a4b8d8a3b9e6ba32
Autor:
Tomas Zikmund, Helena Paszekova, Juraj Kokavec, Paul Kerbs, Shefali Thakur, Tereza Turkova, Petra Tauchmanova, Philipp A. Greif, Tomas Stopka
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2073 (2020)
ISWI chromatin remodeling ATPase SMARCA5 (SNF2H) is a well-known factor for its role in regulation of DNA access via nucleosome sliding and assembly. SMARCA5 transcriptionally inhibits the myeloid master regulator PU.1. Upregulation of SMARCA5 was pr
Externí odkaz:
https://doaj.org/article/b166c7a9913442da974931b8d07ed751
Autor:
Tomas Stopka, Jiri Zavadil, Arthur I. Skoultchi, Dana Mikulenkova, Petra Basova, Juraj Kokavec, Nikola Curik, Pavel Burda
Supplementary Data from PU.1 Activation Relieves GATA-1–Mediated Repression of Cebpa and Cbfb during Leukemia Differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a0dd48882e5556010c90c02a9f8b67
https://doi.org/10.1158/1541-7786.22520710.v1
https://doi.org/10.1158/1541-7786.22520710.v1
Autor:
Tomas Stopka, Jiri Zavadil, Arthur I. Skoultchi, Dana Mikulenkova, Petra Basova, Juraj Kokavec, Nikola Curik, Pavel Burda
Hematopoietic transcription factors GATA-1 and PU.1 bind each other on DNA to block transcriptional programs of undesired lineage during hematopoietic commitment. Murine erythroleukemia (MEL) cells that coexpress GATA-1 and PU.1 are blocked at the bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a19708f4b79214ed40766a767672af
https://doi.org/10.1158/1541-7786.c.6542737
https://doi.org/10.1158/1541-7786.c.6542737
Publikováno v:
Blood. 140:5934-5935
Autor:
Filipp Savvulidi, Arthur I. Skoultchi, Tomas Zikmund, Helena Paszekova, Tomas Stopka, Tereza Turkova, Sona Vodenkova, Radislav Sedlacek, Juraj Kokavec
Publikováno v:
J Immunol
Development of lymphoid progenitors requires a coordinated regulation of gene expression, DNA replication, and gene rearrangement. Chromatin-remodeling activities directed by SWI/SNF2 superfamily complexes play important roles in these processes. In
Autor:
Filipp Savvulidi, Vojtech Kulvait, Arthur I. Skoultchi, Tomas Zikmund, Tomas Stopka, Winfried Edelmann, Juraj Kokavec
Publikováno v:
Stem cells (Dayton, Ohio). 35(6)
The imitation switch nuclear ATPase Smarca5 (Snf2h) is one of the most conserved chromatin remodeling factors. It exists in a variety of oligosubunit complexes that move DNA with respect to the histone octamer to generate regularly spaced nucleosomal
Autor:
Qing Xie, Wei Liu, Lisa A. Brennan, Jiri Zavadil, Tomas Stopka, Marc Kantorow, Juraj Kokavec, Winfried Edelmann, Harry Hou, Arthur I. Skoultchi, Romit Majumdar, Shuying He, Saima Limi, Ales Cvekl, Ruth Ashery-Padan, Rebecca McGreal, Wanda Lee Kantorow
Publikováno v:
Development (Cambridge, England). 143(11)
Ocular lens morphogenesis is a model for investigating mechanisms of cellular differentiation, spatial and temporal gene expression control, and chromatin regulation. Brg1 (Smarca4) and Snf2h (Smarca5) are catalytic subunits of distinct ATP-dependent