Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Juraj Bies"'
Autor:
Linda Wolff, P. Paul Liu, Janet D. Rowley, Michelle M. Le Beau, Michael J. Thirman, Azra Raza, Naomi Galili, Juraj Bies, Matthew T. Garin, Jan Markus
Supplementary Figure 1 from Methylation-Independent Silencing of the Tumor Suppressor INK4b (p15) by CBFβ-SMMHC in Acute Myelogenous Leukemia with inv(16)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f63a79dd46d308bf39ec5c79f901384
https://doi.org/10.1158/0008-5472.22366823.v1
https://doi.org/10.1158/0008-5472.22366823.v1
Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6649a8801e88917050969e78fb350424
https://doi.org/10.1158/0008-5472.22367795.v1
https://doi.org/10.1158/0008-5472.22367795.v1
Autor:
Linda Wolff, P. Paul Liu, Janet D. Rowley, Michelle M. Le Beau, Michael J. Thirman, Azra Raza, Naomi Galili, Juraj Bies, Matthew T. Garin, Jan Markus
Supplementary Figure 1 Legend from Methylation-Independent Silencing of the Tumor Suppressor INK4b (p15) by CBFβ-SMMHC in Acute Myelogenous Leukemia with inv(16)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2005bd3867fc816135d0bf7f81410087
https://doi.org/10.1158/0008-5472.22366826.v1
https://doi.org/10.1158/0008-5472.22366826.v1
Autor:
Linda Wolff, P. Paul Liu, Janet D. Rowley, Michelle M. Le Beau, Michael J. Thirman, Azra Raza, Naomi Galili, Juraj Bies, Matthew T. Garin, Jan Markus
Supplementary Tables 1-2 from Methylation-Independent Silencing of the Tumor Suppressor INK4b (p15) by CBFβ-SMMHC in Acute Myelogenous Leukemia with inv(16)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9daa987667938ca592a130fb2dd476
https://doi.org/10.1158/0008-5472.22366820.v1
https://doi.org/10.1158/0008-5472.22366820.v1
Autor:
Linda Wolff, P. Paul Liu, Janet D. Rowley, Michelle M. Le Beau, Michael J. Thirman, Azra Raza, Naomi Galili, Juraj Bies, Matthew T. Garin, Jan Markus
The tumor suppressor gene INK4b (p15) is silenced by CpG island hypermethylation in most acute myelogenous leukemias (AML), and this epigenetic phenomenon can be reversed by treatment with hypomethylating agents. Thus far, it was not investigated whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1b3b42090284c6ca1457ac64cd471a
https://doi.org/10.1158/0008-5472.c.6495308
https://doi.org/10.1158/0008-5472.c.6495308
The t(2;11)(q31;p15) chromosomal translocation results in a fusion between the NUP98 and HOXD13 genes and has been observed in patients with myelodysplastic syndrome (MDS) or acute myelogenous leukemia. We previously showed that expression of the NUP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e474eccba1783d6ec9bdac368d50343
https://doi.org/10.1158/0008-5472.c.6495692
https://doi.org/10.1158/0008-5472.c.6495692
Publikováno v:
Stem Cells
Homeostasis of hematopoietic stem and progenitor cells is a tightly regulated process. The disturbance of the balance in the hematopoietic progenitor pool can result in favorable conditions for development of diseases such as myelodysplastic syndrome
Autor:
Linda Wolff, Juraj Bies
Publikováno v:
Blood Cells Mol Dis
The p15Ink4b gene is frequently hypermethylated in myeloid neoplasia and has been demonstrated to be a tumor suppressor. Since it is a member of the INK4b family of cyclin-dependent kinase inhibitors, it was initially presumed that its loss in leukem
Publikováno v:
Journal of Virology. 86:10524-10532
Retroviruses integrated into genomic DNA participate in long-range gene activation from as far away as several hundred kilobases. Hypotheses have been put forth to account for these phenomena, but data have not been provided to support a physical mec
Autor:
Martina Pigazzi, Kathleen M. Sakamoto, Er Chieh Cho, Benedetta Accordi, Elena Manara, Christina N. Kraus, Linda Wolff, Elliot M. Landaw, Salemiz Sandoval, Michelle Cho, Juraj Bies
Publikováno v:
Blood. 120:155-165
The cAMP response element-binding protein (CREB) is a nuclear transcription factor that is critical for normal and neoplastic hematopoiesis. Previous studies have demonstrated that CREB is a proto-oncogene whose overexpression promotes cellular proli