Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Juraj, Rievaj"'
Autor:
Van B. Lu, Juraj Rievaj, Elisabeth A. O’Flaherty, Christopher A. Smith, Ramona Pais, Luke A. Pattison, Gwen Tolhurst, Andrew B. Leiter, David C. Bulmer, Fiona M. Gribble, Frank Reimann
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Glucagon-like peptide 1 (GLP-1) is released from intestinal L-cells following nutrient uptake and enhances insulin release as well as promotes satiety. Here, the authors demonstrate that GLP-1 secreting cells release ATP and that this stimulates nodo
Externí odkaz:
https://doaj.org/article/e0d5bffcb836471e9eeb57ed1e965989
Autor:
Gerardo Calderon, Alison McRae, Juraj Rievaj, Judith Davis, Inuk Zandvakili, Sara Linker-Nord, Duane Burton, Geoffrey Roberts, Frank Reimann, Bronislava Gedulin, Adrian Vella, Nicholas F LaRusso, Michael Camilleri, Fiona M Gribble, Andres Acosta
Publikováno v:
EBioMedicine, Vol 55, Iss , Pp - (2020)
Background: The bile acid (BA) pathway plays a role in regulation of food intake and glucose metabolism, based mainly on findings in animal models. Our aim was to determine whether the BA pathway is altered and correctable in human obesity and diabet
Externí odkaz:
https://doaj.org/article/81f621a9ddf64e54b9db7c70d00bcc3d
Publikováno v:
Communications, Vol 18, Iss 2, Pp 72-75 (2016)
Climatologists constantly point to the change of the climate on Earth. They consider CO2 emissions to be one of the main causes of these changes. Transport is significant producer of the greenhouse gases. If one litre of gasoline is burnt, 2.5 kg of
Externí odkaz:
https://doaj.org/article/7784aa538d3844df81d12227434e2419
Autor:
Wanling Pan, Debbie O'Neill, Kennedi Young, Allein Plain, Juraj Rievaj, Matthew Saurette, R. Todd Alexander, Emmanuelle Cordat, Megan R Beggs, Michael R. Doschak, Henrik Dimke
Publikováno v:
Beggs, M R, Young, K, Pan, W, O'Neill, D D, Saurette, M, Plain, A, Rievaj, J, Doschak, M R, Cordat, E, Dimke, H & Alexander, R T 2021, ' Claudin-2 and claudin-12 form independent, complementary pores required to maintain calcium homeostasis ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 48, e2111247118 . https://doi.org/10.1073/pnas.2111247118
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Significant calcium absorption across renal and intestinal epithelia occurs via the paracellular pathway. However, the identity of the paracellular pore involved is unknown. Claudin-2 and claudin-12 contribute paracellular calcium permea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0786e5b44e0f84ac36c93773d69b9b
https://doi.org/10.1073/pnas.2111247118
https://doi.org/10.1073/pnas.2111247118
Autor:
Claire L Meek, Geoffrey P. Roberts, Tristan J Vaughan, Richard G. Kay, Florent Serge Dye, Deborah A. Goldspink, Benjamin G. Challis, Pierre Larraufie, Maria A T Groves, Fiona M. Gribble, Frank Reimann, Franco Ferraro, Stephen J. Middleton, Juraj Rievaj, Richard H. Hardwick, Jennifer L. Percival-Alwyn, Tamana Darwish, Stephen O'Rahilly
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-20 (2019)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-52049-0⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-52049-0⟩
Guanylin, a peptide implicated in regulation of intestinal fluid secretion, is expressed in the mucosa, but the exact cellular origin remains controversial. In a new transgenic mouse model fluorescent reporter protein expression driven by the proguan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d3c9a4afb8d35913618034046ac232
http://link.springer.com/article/10.1038/s41598-019-52049-0
http://link.springer.com/article/10.1038/s41598-019-52049-0
Autor:
Juraj Rievaj, Gerardo Calderon, Michael Camilleri, Bronislava Gedulin, Nicholas F. LaRusso, Fiona M. Gribble, Adrian Vella, Geoffrey P. Roberts, Frank Reimann, Alison Mcrae, Duane Burton, Sara Linker-Nord, Inuk Zandvakili, Judith Davis, Andres Acosta
Publikováno v:
EBioMedicine
EBioMedicine, Vol 55, Iss, Pp-(2020)
EBioMedicine, Vol 55, Iss, Pp-(2020)
Background The bile acid (BA) pathway plays a role in regulation of food intake and glucose metabolism, based mainly on findings in animal models. Our aim was to determine whether the BA pathway is altered and correctable in human obesity and diabete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336f9d4f40e534e6cfaa4225dc9ded7e
Autor:
Frank Reimann, Fiona M. Gribble, Andres Acosta, Duane Burton, Geoffrey P. Roberts, Judith Davis, Adrian Vella, Inuk Zandvakili, Juraj Rievaj, Michael Camilleri, Bronislava Gedulin, Nicholas F. LaRusso, Gerardo Calderon, Sara Linker Nord, Alison Mcrae
Publikováno v:
SSRN Electronic Journal.
Background: The bile acid (BA) pathway plays a role in regulation of food intake and glucose metabolism, based mainly on findings in animal models. Our aim was to determine whether the BA pathway is altered and correctable in human obesity and diabet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e79806aee71a0d0f9b8155b3ac3387af
https://doi.org/10.2139/ssrn.3517409
https://doi.org/10.2139/ssrn.3517409
Autor:
Agata Kranjc, Federico W Grillo, Juraj Rievaj, Anna Boccaccio, Fabio Pietrucci, Anna Menini, Paolo Carloni, Claudio Anselmi
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4672 (2009)
Bestrophins are a recently discovered family of Cl(-) channels, for which no structural information is available. Some family members are activated by increased intracellular Ca2+ concentration. Bestrophins feature a well conserved Asp-rich tract in
Externí odkaz:
https://doaj.org/article/b5372c9801fb4120aad2f414c9804251
Publikováno v:
Alexander, R T, Rievaj, J & Dimke, H 2014, ' Paracellular calcium transport across renal and intestinal epithelia ', Biochemistry and Cell Biology, vol. 92, no. 6, pp. 467-480 . https://doi.org/10.1139/bcb-2014-0061
Calcium (Ca2+) is a key constituent in a myriad of physiological processes from intracellular signalling to the mineralization of bone. As a consequence, Ca2+is maintained within narrow limits when circulating in plasma. This is accomplished via regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106a67bc4f75f60656105951afd0f81d
https://doi.org/10.1139/bcb-2014-0061
https://doi.org/10.1139/bcb-2014-0061
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 305:G303-G313
Intestinal calcium (Ca2+) absorption occurs via paracellular and transcellular pathways. Although the transcellular route has been extensively studied, mechanisms mediating paracellular absorption are largely unexplored. Unlike passive diffusion, sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::392d2db47ad6291631118a3fed69f1a7
https://doi.org/10.1152/ajpgi.00490.2012
https://doi.org/10.1152/ajpgi.00490.2012